Edwin Cuppen

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Citations	49339	28574
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Hans CleversHubrecht Institute - UtrechtVerified email at hubrecht.eu
Victor GuryevEuropean Research Institute for the Biology of Ageing, University of GroningenVerified email at umcg.nl
Ronald PlasterkVerified email at tiscali.nl
I.J. NijmanVerified email at umcutrecht.nl
Eugene BerezikovUMCGVerified email at umcg.nl
Neeltje SteeghsMD, PhD, Netherlands Cancer InstituteVerified email at nki.nl
Judith HombergAssociate professorVerified email at radboudumc.nl
Joep de LigtLead Data @ Hartwig Medical Foundation (NL)Verified email at hartwigmedicalfoundation.nl
Bart MG SmitsVerified email at musc.edu
Ewart KuijkWKZ UMC Utrecht, Regenerative Medicine Center UtrechtVerified email at umcutrecht.nl
B Ellenbroekvictoria university wellingtonVerified email at vuw.ac.nz
Sebastiaan van HeeschGroup Leader at Princess Máxima Center for Pediatric OncologyVerified email at prinsesmaximacentrum.nl
Lodewyk WesselsProfessor of Computational Cancer BiologyVerified email at nki.nl
EF. SmitHoogleraar longziektenVerified email at nki.nl
Erno WienholdsPrincess Margaret Cancer CentreVerified email at uhn.ca
Gerrit A Meijerprofessor of oncologic pathology, Netherlands Cancer Institute, University Medical Center UtrechtVerified email at nki.nl
Pantelis HatzisBSRC Alexander FlemingVerified email at fleming.gr
Luc van der LaanProfessor at Erasmus MC-University Medical center RotterdamVerified email at erasmusmc.nl
Bon-Kyoung KooCenter for Genome Engineering (CGE), Institute for Basic Science (IBS)Verified email at ibs.re.kr
Helmuth GehartInstitute for Molecular Health Sciences, ETH ZurichVerified email at biol.ethz.ch

Edwin Cuppen

Hoogleraar Humane Genetica

Verified email at umcutrecht.nl - Homepage

Genetica genomics structurele variatie integratieve biologie


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Organoid models of human and mouse ductal pancreatic cancer SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ... Cell 160 (1), 324-338, 2015	2025	2015
Sambamba: fast processing of NGS alignment formats A Tarasov, AJ Vilella, E Cuppen, IJ Nijman, P Prins Bioinformatics 31 (12), 2032-2034, 2015	1773	2015
SARS-CoV-2 productively infects human gut enterocytes MM Lamers, J Beumer, J van der Vaart, K Knoops, J Puschhof, ... Science 369 (6499), 50-54, 2020	1770	2020
Phylogenetic shadowing and computational identification of human microRNA genes E Berezikov, V Guryev, J van de Belt, E Wienholds, RHA Plasterk, ... Cell 120 (1), 21-24, 2005	1712	2005
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients G Schwank, BK Koo, V Sasselli, JF Dekkers, I Heo, T Demircan, N Sasaki, ... Cell stem cell 13 (6), 653-658, 2013	1653	2013
A living biobank of breast cancer organoids captures disease heterogeneity N Sachs, J De Ligt, O Kopper, E Gogola, G Bounova, F Weeber, ... Cell 172 (1), 373-386. e10, 2018	1638	2018
Long-term culture of genome-stable bipotent stem cells from adult human liver M Huch, H Gehart, R Van Boxtel, K Hamer, F Blokzijl, MMA Verstegen, ... Cell 160 (1), 299-312, 2015	1545	2015
Mammalian mirtron genes E Berezikov, WJ Chung, J Willis, E Cuppen, EC Lai Molecular cell 28 (2), 328-336, 2007	1126	2007
Sequential cancer mutations in cultured human intestinal stem cells J Drost, RH Van Jaarsveld, B Ponsioen, C Zimberlin, R Van Boxtel, ... Nature 521 (7550), 43-47, 2015	1097	2015
Tissue-specific mutation accumulation in human adult stem cells during life F Blokzijl, J De Ligt, M Jager, V Sasselli, S Roerink, N Sasaki, M Huch, ... Nature 538 (7624), 260-264, 2016	913	2016
Pan-cancer whole-genome analyses of metastatic solid tumours P Priestley, J Baber, MP Lolkema, N Steeghs, E de Bruijn, C Shale, ... Nature 575 (7781), 210-216, 2019	883	2019
Long‐term expanding human airway organoids for disease modeling N Sachs, A Papaspyropoulos, DD Zomer‐van Ommen, I Heo, L Böttinger, ... The EMBO journal 38 (4), e100300, 2019	839	2019
Mutational signature in colorectal cancer caused by genotoxic pks⁺E. coli C Pleguezuelos-Manzano, J Puschhof, A Rosendahl Huber, A van Hoeck, ... Nature 580 (7802), 269-273, 2020	802	2020
Identification of multipotent luminal progenitor cells in human prostate organoid cultures WR Karthaus, PJ Iaquinta, J Drost, A Gracanin, R Van Boxtel, J Wongvipat, ... Cell 159 (1), 163-175, 2014	749	2014
A systematic genome-wide analysis of zebrafish protein-coding gene function RNW Kettleborough, EM Busch-Nentwich, SA Harvey, CM Dooley, ... Nature 496 (7446), 494-497, 2013	717	2013
Diversity of microRNAs in human and chimpanzee brain E Berezikov, F Thuemmler, LW Van Laake, I Kondova, R Bontrop, ... Nature genetics 38 (12), 1375-1377, 2006	636	2006
Approaches to microRNA discovery E Berezikov, E Cuppen, RHA Plasterk Nature genetics 38 (Suppl 6), S2-S7, 2006	617	2006
The microRNA-producing enzyme Dicer1 is essential for zebrafish development E Wienholds, MJ Koudijs, FJM van Eeden, E Cuppen, RHA Plasterk Nature genetics 35 (3), 217-218, 2003	605	2003
MutationalPatterns: comprehensive genome-wide analysis of mutational processes F Blokzijl, R Janssen, R Van Boxtel, E Cuppen Genome medicine 10, 1-11, 2018	599	2018
Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients SN Ooft, F Weeber, KK Dijkstra, CM McLean, S Kaing, E van Werkhoven, ... Science translational medicine 11 (513), eaay2574, 2019	591	2019

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