| Mechanism and catalysis of nucleophilic substitution in phosphate esters RJG Thatcher, R Kluger Advances in Physical Organic Chemistry 25, 99-265, 1989 | 415 | 1989 |
| Potential mechanisms of estrogen quinone carcinogenesis JL Bolton, GRJ Thatcher Chemical research in toxicology 21 (1), 93-101, 2008 | 307 | 2008 |
| The anomeric effect and associated stereoelectronic effects GRJ Thatcher Washington, DC: American Chemical Society, 1871 | 282 | 1871 |
| Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors M Siklos, M BenAissa, GRJ Thatcher Acta Pharmaceutica Sinica B 5 (6), 506-519, 2015 | 268 | 2015 |
| Phosphonates as analogues of biological phosphates GM Blackburn | 198 | 1981 |
| Nitrates and NO release: contemporary aspects in biological and medicinal chemistry GRJ Thatcher, AC Nicolescu, BM Bennett, V Toader Free Radical Biology and Medicine 37 (8), 1122-1143, 2004 | 191 | 2004 |
| Benzothiophene selective estrogen receptor modulators with modulated oxidative activity and receptor affinity Z Qin, I Kastrati, REP Chandrasena, H Liu, P Yao, PA Petukhov, JL Bolton, ... Journal of Medicinal Chemistry 50 (11), 2682-2692, 2007 | 174 | 2007 |
| Phosphonates as mimics of phosphate biomolecules: ab initio calculations on tetrahedral ground states and pentacoordinate intermediates for phosphoryl transfer GRJ Thatcher, AS Campbell The Journal of Organic Chemistry 58 (8), 2272-2281, 1993 | 170 | 1993 |
| Dimethyl fumarate inhibits the nuclear factor κB pathway in breast cancer cells by covalent modification of p65 protein I Kastrati, MI Siklos, EL Calderon-Gierszal, L El-Shennawy, G Georgieva, ... Journal of Biological Chemistry 291 (7), 3639-3647, 2016 | 140 | 2016 |
| GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway SS Pathi, I Jutooru, G Chadalapaka, S Sreevalsan, S Anand, ... Molecular Cancer Research 9 (2), 195-202, 2011 | 139 | 2011 |
| Design of SARS-CoV-2 PLpro inhibitors for COVID-19 antiviral therapy leveraging binding cooperativity Z Shen, K Ratia, L Cooper, D Kong, H Lee, Y Kwon, Y Li, S Alqarni, ... Journal of medicinal chemistry 65 (4), 2940-2955, 2021 | 123 | 2021 |
| Oxidation of Raloxifene to Quinoids: Potential Toxic Pathways via a Diquinone Methide and o-Quinones L Yu, H Liu, W Li, F Zhang, C Luckie, RB van Breemen, GRJ Thatcher, ... Chemical research in toxicology 17 (7), 879-888, 2004 | 109 | 2004 |
| Furoxans (1,2,5-Oxadiazole-N-Oxides) as Novel NO Mimetic Neuroprotective and Procognitive Agents IT Schiefer, L VandeVrede, M Fa’, O Arancio, GRJ Thatcher Journal of medicinal chemistry 55 (7), 3076-3087, 2012 | 100 | 2012 |
| Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo LM Tai, KP Koster, J Luo, SH Lee, Y Wang, NC Collins, MB Aissa, ... Journal of Biological Chemistry 289 (44), 30538-30555, 2014 | 98 | 2014 |
| Bioactivation of the selective estrogen receptor modulator desmethylated arzoxifene to quinoids: 4 ‘-Fluoro substitution prevents quinoid formation H Liu, J Liu, RB van Breemen, GRJ Thatcher, JL Bolton Chemical research in toxicology 18 (2), 162-173, 2005 | 97 | 2005 |
| Role of mitochondrial aldehyde dehydrogenase in nitrate tolerance J DiFabio, Y Ji, V Vasiliou, GRJ Thatcher, BM Bennett Molecular pharmacology 64 (5), 1109-1116, 2003 | 91 | 2003 |
| NO problem for nitroglycerin: organic nitrate chemistry and therapy GRJ Thatcher Chemical Society Reviews 27 (5), 331-337, 1998 | 91 | 1998 |
| Nitric oxide mimetic molecules as therapeutic agents in Alzheimer's disease GRJ Thatcher, BM Bennett, JN Reynolds Current Alzheimer Research 2 (2), 171-182, 2005 | 90 | 2005 |
| In vitro activation of soluble guanylyl cyclase and nitric oxide release: a comparison of NO donors and NO mimetics JD Artz, V Toader, SI Zavorin, BM Bennett, GRJ Thatcher Biochemistry 40 (31), 9256-9264, 2001 | 90 | 2001 |
| Synthesis of monofacially functionalized cyclodextrins bearing amino pendent groups D Vizitiu, CS Walkinshaw, BI Gorin, GRJ Thatcher The Journal of Organic Chemistry 62 (25), 8760-8766, 1997 | 89 | 1997 |
