| How similar are similarity searching methods? A principal component analysis of molecular descriptor space A Bender, JL Jenkins, J Scheiber, SCK Sukuru, M Glick, JW Davies Journal of chemical information and modeling 49 (1), 108-119, 2009 | 337 | 2009 |
| Mapping adverse drug reactions in chemical space J Scheiber, JL Jenkins, SCK Sukuru, A Bender, D Mikhailov, M Milik, ... Journal of medicinal chemistry 52 (9), 3103-3107, 2009 | 196 | 2009 |
| Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis J Scheiber, B Chen, M Milik, SCK Sukuru, A Bender, D Mikhailov, ... Journal of chemical information and modeling 49 (2), 308-317, 2009 | 193 | 2009 |
| Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications A Maderna, M Doroski, C Subramanyam, A Porte, CA Leverett, ... Journal of medicinal chemistry 57 (24), 10527-10543, 2014 | 140 | 2014 |
| PALI—a database of Phylogeny and ALIgnment of homologous protein structures S Balaji, S Sujatha, SSC Kumar, N Srinivasan Nucleic Acids Research 29 (1), 61-65, 2001 | 125 | 2001 |
| Plate-based diversity selection based on empirical HTS data to enhance the number of hits and their chemical diversity SCK Sukuru, JL Jenkins, REJ Beckwith, J Scheiber, A Bender, ... SLAS Discovery 14 (6), 690-699, 2009 | 88 | 2009 |
| Optimization of tubulysin antibody–drug conjugates: a case study in addressing ADC metabolism LN Tumey, CA Leverett, B Vetelino, F Li, B Rago, X Han, F Loganzo, ... ACS Medicinal Chemistry Letters 7 (11), 977-982, 2016 | 79 | 2016 |
| Discovering New Classes of Brugia malayi Asparaginyl-tRNA Synthetase Inhibitors and Relating Specificity to Conformational Change SCK Sukuru, T Crepin, Y Milev, LC Marsh, JB Hill, RJ Anderson, ... Journal of computer-aided molecular design 20, 159-178, 2006 | 56 | 2006 |
| The structure of urease activation complexes examined by flexibility analysis, mutagenesis, and small-angle X-ray scattering S Quiroz-Valenzuela, SCK Sukuru, RP Hausinger, LA Kuhn, WT Heller Archives of Biochemistry and Biophysics 480 (1), 51-57, 2008 | 48 | 2008 |
| “Virtual fragment linking”: an approach to identify potent binders from low affinity fragment hits TJ Crisman, A Bender, M Milik, JL Jenkins, J Scheiber, SCK Sukuru, ... Journal of medicinal chemistry 51 (8), 2481-2491, 2008 | 44 | 2008 |
| Design, synthesis, and cytotoxic evaluation of novel tubulysin analogues as ADC payloads CA Leverett, SCK Sukuru, BC Vetelino, S Musto, K Parris, J Pandit, ... ACS Medicinal Chemistry Letters 7 (11), 999-1004, 2016 | 35 | 2016 |
| New cytotoxic benzosuberene analogs. Synthesis, molecular modeling and biological evaluation Z Chen, A Maderna, SCK Sukuru, M Wagenaar, CJ O’Donnell, MH Lam, ... Bioorganic & medicinal chemistry letters 23 (24), 6688-6694, 2013 | 22 | 2013 |
| A lead discovery strategy driven by a comprehensive analysis of proteases in the peptide substrate space SCK Sukuru, F Nigsch, J Quancard, M Renatus, R Chopra, N Brooijmans, ... Protein Science 19 (11), 2096-2109, 2010 | 9 | 2010 |
| Discovery of new auristatins for the use on antibody drug conjugates for the treatment of cancer A Maderna, M Doroski, H Risley, A Porte, Z Chen, C Subramanyam, ... Abstracts of Papers of the American Chemical Society 246, 2013 | 2 | 2013 |
| SPREAD—exploiting chemical features that cause differential activity behavior J Scheiber, JL Jenkins, A Bender, M Milik, D Mikhailov, SCK Sukuru, ... Statistical Analysis and Data Mining: The ASA Data Science Journal 2 (2 …, 2009 | 1 | 2009 |
| Tubulysin analogs and methods for their preparation C Subramanyam, LN Tumey, L Xie, C Leverett, BC Vetelino, SCK Sukuru, ... US Patent 10,723,727, 2020 | | 2020 |
| Tubulysin analogs and methods for their preparation C Subramanyam, LN Tumey, L Xie, CA LEVERETT, BC VETELINO, ... | | 2017 |
| Towards Addressing Informatics Challenges Presented by Antibody Drug Conjugates C Sukuru, T Zhang, L Tumey, E Muszynska, M Tran, F Loganzo ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |
| Benzosuberenes as cytotoxic tubulin binding agents Z Chen, A Maderna, C Sukuru, F Loganzo ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012 | | 2012 |
| Structural and statistical investigation of the trimethoxy-phenyl moiety in potent compounds that modulate multiple target classes SCK Sukuru, JA Bikker, CJ O'Donnell ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 242, 2011 | | 2011 |
Jeremy L. JenkinsUS Head Discovery Sciences, Novartis Institutes for BioMedical ResearchΗ διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα novartis.com
