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Keith L. Ligon
Keith L. Ligon
Associate Professor, Harvard Medical School
Verified email at dfci.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Integrative analysis of 111 reference human epigenomes
A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ...
Nature 518 (7539), 317-330, 2015
60192015
Malignant astrocytic glioma: genetics, biology, and paths to treatment
FB Furnari, T Fenton, RM Bachoo, A Mukasa, JM Stommel, A Stegh, ...
Genes & development 21 (21), 2683-2710, 2007
28862007
An integrative model of cellular states, plasticity, and genetics for glioblastoma
C Neftel, J Laffy, MG Filbin, T Hara, ME Shore, GJ Rahme, AR Richman, ...
Cell 178 (4), 835-849. e21, 2019
17062019
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
DB Keskin, AJ Anandappa, J Sun, I Tirosh, ND Mathewson, S Li, ...
Nature 565 (7738), 234-239, 2019
11302019
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
JM Stommel, AC Kimmelman, H Ying, R Nabioullin, AH Ponugoti, ...
Science 318 (5848), 287-290, 2007
11162007
p16INK4a induces an age-dependent decline in islet regenerative potential
J Krishnamurthy, MR Ramsey, KL Ligon, C Torrice, A Koh, S Bonner-Weir, ...
Nature 443 (7110), 453-457, 2006
11012006
Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets
PK Brastianos, SL Carter, S Santagata, DP Cahill, A Taylor-Weiner, ...
Cancer discovery 5 (11), 1164-1177, 2015
10042015
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ...
Nature 455 (7216), 1129-1133, 2008
8562008
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
RM Bachoo, EA Maher, KL Ligon, NE Sharpless, SS Chan, MJ You, ...
Cancer cell 1 (3), 269-277, 2002
8362002
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
YJ Cho, A Tsherniak, P Tamayo, S Santagata, A Ligon, H Greulich, ...
Journal of clinical oncology 29 (11), 1424, 2011
8342011
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
P Koivunen, S Lee, CG Duncan, G Lopez, G Lu, S Ramkissoon, ...
Nature 483 (7390), 484-488, 2012
8282012
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927-932, 2013
8022013
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
U Schüller, VM Heine, J Mao, AT Kho, AK Dillon, YG Han, E Huillard, ...
Cancer cell 14 (2), 123-134, 2008
7222008
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
PK Brastianos, PM Horowitz, S Santagata, RT Jones, A McKenna, G Getz, ...
Nature genetics 45 (3), 285-289, 2013
6842013
Emerging insights into the molecular and cellular basis of glioblastoma
GP Dunn, ML Rinne, J Wykosky, G Genovese, SN Quayle, IF Dunn, ...
Genes & development 26 (8), 756-784, 2012
6612012
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma
KL Ligon, E Huillard, S Mehta, S Kesari, H Liu, JA Alberta, RM Bachoo, ...
Neuron 53 (4), 503-517, 2007
5862007
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination
B Emery, D Agalliu, JD Cahoy, TA Watkins, JC Dugas, SB Mulinyawe, ...
Cell 138 (1), 172-185, 2009
5612009
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ...
Science 360 (6386), 331-335, 2018
5502018
Delivery of functional anti-miR-9 by mesenchymal stem cell–derived exosomes to glioblastoma multiforme cells conferred chemosensitivity
JL Munoz, SA Bliss, SJ Greco, SH Ramkissoon, KL Ligon, P Rameshwar
Molecular Therapy-Nucleic Acids 2, 2013
5352013
Targetable genetic features of primary testicular and primary central nervous system lymphomas
B Chapuy, MGM Roemer, C Stewart, Y Tan, RP Abo, L Zhang, AJ Dunford, ...
Blood, The Journal of the American Society of Hematology 127 (7), 869-881, 2016
5252016
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