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Adam De Jesus
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Hexokinase 1 cellular localization regulates the metabolic fate of glucose
A De Jesus, F Keyhani-Nejad, CM Pusec, L Goodman, JA Geier, ...
Molecular cell 82 (7), 1261-1277. e9, 2022
502022
Targeting latent TGFβ release in muscular dystrophy
E Ceco, S Bogdanovich, B Gardner, T Miller, A DeJesus, JU Earley, ...
Science translational medicine 6 (259), 259ra144-259ra144, 2014
502014
Hepatic HKDC1 expression contributes to liver metabolism
CM Pusec, A De Jesus, MW Khan, AR Terry, AE Ludvik, K Xu, N Giancola, ...
Endocrinology 160 (2), 313-330, 2019
462019
Hepatocyte-specific loss of PPARγ protects mice from NASH and increases the therapeutic effects of rosiglitazone in the liver
SM Lee, CM Pusec, GH Norris, A De Jesus, A Diaz-Ruiz, J Muratalla, ...
Cellular and molecular gastroenterology and hepatology 11 (5), 1291-1311, 2021
332021
Hepatic tristetraprolin promotes insulin resistance through RNA destabilization of FGF21
KT Sawicki, HC Chang, JS Shapiro, M Bayeva, A De Jesus, BN Finck, ...
JCI insight 3 (13), 2018
322018
Iron metabolism in cardiovascular disease: physiology, mechanisms, and therapeutic targets
KT Sawicki, A De Jesus, H Ardehali
Circulation research 132 (3), 379-396, 2023
242023
ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice
H Kouzu, Y Tatekoshi, HC Chang, JS Shapiro, WA McGee, A De Jesus, ...
The Journal of Clinical Investigation 132 (10), 2022
112022
Iron drives anabolic metabolism through active histone demethylation and mTORC1
JS Shapiro, HC Chang, Y Tatekoshi, Z Zhao, ZS Waxali, BJ Hong, H Chen, ...
Nature Cell Biology 25 (10), 1478-1494, 2023
62023
Optimized protocol to isolate primary mouse peritoneal macrophage metabolites
A De Jesus, CM Pusec, T Nguyen, F Keyhani-Nejad, P Gao, SE Weinberg, ...
STAR protocols 3 (4), 101668, 2022
32022
Metabolic suppression of HIF-1α contributes to susceptibility of ischemic injury in diabetic hearts
A De Jesus, HC Chang, H Ardehali
JACC: Basic to Translational Science 3 (4), 499-502, 2018
32018
Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity
CM Pusec, V Ilievski, A De Jesus, Z Farooq, JL Zapater, N Sweis, H Ismail, ...
Scientific reports 13 (1), 8034, 2023
12023
Hexokinase-1 mitochondrial dissociation and protein O-GlcNAcylation drive heart failure with preserved ejection fraction.
H Ardehali, Y Tatekoshi, J Shapiro, M Liu, G Bianco, A Tatekoshi, ...
Research Square, rs. 3. rs-2448086, 2023
12023
The Jumonji-C Histone Lysine Demethylase KDM3B Senses Cellular Iron to Regulate Anabolism Through mTORC1
J Shapiro, HC Chang, Z Zhao, J Geier, E Bartom, C Chen, Y Chen, ...
12022
DNA damage and nuclear morphological changes in cardiac hypertrophy are mediated by SNRK through actin depolymerization
PJ Stanczyk, Y Tatekoshi, JS Shapiro, K Nayudu, Y Chen, Z Zilber, ...
Circulation 148 (20), 1582-1592, 2023
2023
Hexokinase-1 mitochondrial dissociation and protein O-GlcNAcylation drive heart failure with preserved ejection fraction
Y Tatekoshi, J Shapiro, M Liu, G Bianco, A Tatekoshi, A De Jesus, ...
2023
[WITHDRAWN] Hexokinase-1 mitochondrial dissociation and protein O-GlcNAcylation drive heart failure with preserved ejection fraction
Y Tatekoshi, JS Shapiro, M Liu, GM Bianco, A Tatekoshi, A De Jesus, ...
Research Square, 2023
2023
A Novel Mechanism in the Pathogenesis of Heart Failure With Preserved Ejection Fraction Through Hexokinase Mitochondrial Dislocation and Substrate Shuttling Into the O …
Y Tatekoshi, JS Shapiro, M Liu, GM Bianco, F Sharifzad, A De Jesus, ...
Circulation 146 (Suppl_1), A12874-A12874, 2022
2022
Meet the authors: Adam De Jesus and Hossein Ardehali
A De Jesus
Molecular Cell 82 (7), 1239-1243, 2022
2022
HEPATOCYTE PPARGAMMA NEGATIVELY REGULATES METHIONINE METABOLISM AND CONTRIBUTES TO THE DEVELOPMENT OF NASH
SM Lee, CM Pusec, A De Jesus, BT Layden, JC Chacon
The Liver Meeting Digital Experience™, 2020
2020
Role of Snf1-related Kinase as a Regulator of Chromatin Modifications and Dna-damage Response in Heart Injury
PJ Stanczyk, Z Zilber, A de Jesus, HC Chang, H Ardehali
Circulation Research 125 (Suppl_1), A308-A308, 2019
2019
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Articles 1–20