Spyros S. Skandalis, PhD
Spyros S. Skandalis, PhD
Assoc. Prof. of Biochemistry, University of Patras
Verified email at
Cited by
Cited by
Extracellular matrix structure
AD Theocharis, SS Skandalis, C Gialeli, NK Karamanos
Advanced drug delivery reviews 97, 4-27, 2016
Hyaluronan–CD44 interactions as potential targets for cancer therapy
S Misra, P Heldin, VC Hascall, NK Karamanos, SS Skandalis, ...
The FEBS journal 278 (9), 1429-1443, 2011
Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting
AD Theocharis, SS Skandalis, GN Tzanakakis, NK Karamanos
The FEBS journal 277 (19), 3904-3923, 2010
A guide to the composition and functions of the extracellular matrix
NK Karamanos, AD Theocharis, Z Piperigkou, D Manou, A Passi, ...
The FEBS journal 288 (24), 6850-6912, 2021
Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: focus on the role and impact of proteoglycans
SS Skandalis, N Afratis, G Smirlaki, D Nikitovic, AD Theocharis, ...
Matrix Biology 35, 182-193, 2014
Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer
E Karousou, S Misra, S Ghatak, K Dobra, M Götte, D Vigetti, A Passi, ...
Matrix Biology 59, 3-22, 2017
Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells
P Bouris, SS Skandalis, Z Piperigkou, N Afratis, K Karamanou, AJ Aletras, ...
Matrix Biology 43, 42-60, 2015
Insights into the key roles of proteoglycans in breast cancer biology and translational medicine
AD Theocharis, SS Skandalis, T Neill, HAB Multhaupt, M Hubo, H Frey, ...
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1855 (2), 276-300, 2015
Altered content composition and structure of glycosaminoglycans and proteoglycans in gastric carcinoma
AD Theocharis, DH Vynios, N Papageorgakopoulou, SS Skandalis, ...
The international journal of biochemistry & cell biology 35 (3), 376-390, 2003
Serglycin: at the crossroad of inflammation and malignancy
A Korpetinou, SS Skandalis, VT Labropoulou, G Smirlaki, A Noulas, ...
Frontiers in oncology 3, 327, 2014
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination
E Karousou, M Kamiryo, SS Skandalis, A Ruusala, T Asteriou, A Passi, ...
Journal of Biological Chemistry 285 (31), 23647-23654, 2010
Regulation of hyaluronan biosynthesis and clinical impact of excessive hyaluronan production
P Heldin, CY Lin, C Kolliopoulos, YH Chen, SS Skandalis
Matrix Biology 78, 100-117, 2019
Importance of hyaluronan-CD44 interactions in inflammation and tumorigenesis
P Heldin, E Karousou, B Bernert, H Porsch, K Nishitsuka, SS Skandalis
Connective tissue research 49 (3-4), 215-218, 2008
Hyaluronan-CD44 axis orchestrates cancer stem cell functions
SS Skandalis, TT Karalis, A Chatzopoulos, NK Karamanos
Cellular signalling 63, 109377, 2019
Cell–matrix interactions: focus on proteoglycan–proteinase interplay and pharmacological targeting in cancer
AD Theocharis, C Gialeli, P Bouris, E Giannopoulou, SS Skandalis, ...
The FEBS journal 281 (22), 5023-5042, 2014
The greatly increased amounts of accumulated versican and decorin with specific post-translational modifications may be closely associated with the malignant phenotype of†…
SS Skandalis, D Kletsas, D Kyriakopoulou, M Stavropoulos, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1760 (8), 1217-1225, 2006
Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors
TT Karalis, P Heldin, DH Vynios, T Neill, S Buraschi, RV Iozzo, ...
Matrix Biology 78, 118-138, 2019
Intracellular hyaluronan: Importance for cellular functions
SS Skandalis, T Karalis, P Heldin
Seminars in cancer biology 62, 20-30, 2020
Interplay between Šv‚3 integrin and nucleolin regulates human endothelial and glioma cell migration
M Koutsioumpa, C Polytarchou, J Courty, Y Zhang, N Kieffer, C Mikelis, ...
Journal of Biological Chemistry 288 (1), 343-354, 2013
Extracellular matrix degradation and tissue remodeling in periprosthetic loosening and osteolysis: focus on matrix metalloproteinases, their endogenous tissue inhibitors, and†…
SA Syggelos, AJ Aletras, I Smirlaki, SS Skandalis
BioMed research international 2013 (1), 230805, 2013
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