Jayne Stommel
Jayne Stommel
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Malignant astrocytic glioma: genetics, biology, and paths to treatment
FB Furnari, T Fenton, RM Bachoo, A Mukasa, JM Stommel, A Stegh, ...
Genes & development 21 (21), 2683-2710, 2007
Pancreatic cancers require autophagy for tumor growth
S Yang, X Wang, G Contino, M Liesa, E Sahin, H Ying, A Bause, Y Li, ...
Genes & development 25 (7), 717-729, 2011
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
JM Stommel, AC Kimmelman, H Ying, R Nabioullin, AH Ponugoti, ...
Science 318 (5848), 287-290, 2007
A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking
JM Stommel, ND Marchenko, GS Jimenez, UM Moll, TJ Hope, GM Wahl
The EMBO journal 18 (6), 1660-1672, 1999
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ...
Nature 455 (7216), 1129-1133, 2008
Accelerated MDM2 auto‐degradation induced by DNA‐damage kinases is required for p53 activation
JM Stommel, GM Wahl
The EMBO journal 23 (7), 1547-1556, 2004
A transactivation-deficient mouse model provides insights into Trp53 regulation and function
GS Jimenez, M Nister, JM Stommel, M Beeche, EA Barcarse, XQ Zhang, ...
Nature genetics 26 (1), 37-43, 2000
p53 regulation by post-translational modification and nuclear retention in response to diverse stresses
GS Jimenez, SH Khan, JM Stommel, GM Wahl
Oncogene 18 (53), 7656-7665, 1999
Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCFâ-TRCP ubiquitin ligase
H Inuzuka, A Tseng, D Gao, B Zhai, Q Zhang, S Shaik, L Wan, XL Ang, ...
Cancer cell 18 (2), 147-159, 2010
Hdmx modulates the outcome of p53 activation in human tumor cells
M Wade, ET Wong, M Tang, JM Stommel, GM Wahl
Journal of Biological Chemistry 281 (44), 33036-33044, 2006
Mig-6 controls EGFR trafficking and suppresses gliomagenesis
H Ying, H Zheng, K Scott, R Wiedemeyer, H Yan, C Lim, J Huang, ...
Proceedings of the National Academy of Sciences 107 (15), 6912-6917, 2010
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma
H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ...
Cold Spring Harbor symposia on quantitative biology 73, 427-437, 2008
A new twist in the feedback loop: stress-activated MDM2 destabilization is required for p53 activation
JM Stommel, GM Wahl
Cell cycle 4 (3), 411-417, 2005
Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy
M Nitta, D Kozono, R Kennedy, J Stommel, K Ng, PO Zinn, D Kushwaha, ...
PloS one 5 (5), e10767, 2010
The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans
DR Carrasco, T Fenton, K Sukhdeo, M Protopopova, M Enos, MJ You, ...
Cancer cell 9 (5), 379-390, 2006
CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level
G Yuen, FJ Khan, S Gao, JM Stommel, E Batchelor, X Wu, J Luo
Nucleic acids research 45 (20), 12039-12053, 2017
Cholesterol metabolism: A potential therapeutic target in glioblastoma
F Ahmad, Q Sun, D Patel, JM Stommel
Cancers 11 (2), 146, 2019
v-Raf activates transcription of growth-responsive promoters via GC-rich sequences that bind the transcription factor Sp1.
RJ Miltenberger, PJ Farnham, DE Smith, JM Stommel, MM Cornwell
Cell Growth & Differentiation: the Molecular Biology Journal of the American …, 1995
Global inhibition with specific activation: how p53 and MYC redistribute the transcriptome in the DNA double-strand break response
JR Porter, BE Fisher, L Baranello, JC Liu, DM Kambach, Z Nie, WS Koh, ...
Molecular cell 67 (6), 1013-1025. e9, 2017
Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma
DM Kambach, AS Halim, AG Cauer, Q Sun, CA Tristan, O Celiku, ...
Oncotarget 8 (9), 14860, 2017
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