| Crystal structures of apo-and holo-bovine α-lactalbumin at 2.2-Å resolution reveal an effect of calcium on inter-lobe interactions ED Chrysina, K Brew, KR Acharya Journal of Biological Chemistry 275 (47), 37021-37029, 2000 | 341 | 2000 |
| New inhibitors of glycogen phosphorylase as potential antidiabetic agents L Somsák, K Czifrák, M Tóth, E Bokor, ED Chrysina, KM Alexacou, ... Current medicinal chemistry 15 (28), 2933-2983, 2008 | 221 | 2008 |
| The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor SE Zographos, NG Oikonomakos, KE Tsitsanou, DD Leonidas, ... Structure 5 (11), 1413-1425, 1997 | 111 | 1997 |
| Kinetic and crystallographic studies on 2‐(β‐D‐glucopyranosyl)‐5‐methyl‐1, 3, 4‐oxadiazole,‐benzothiazole, and‐benzimidazole, inhibitors of muscle glycogen phosphorylase b … ED Chrysina, MN Kosmopoulou, C Tiraidis, R Kardakaris, N Bischler, ... Protein science 14 (4), 873-888, 2005 | 110 | 2005 |
| Glucose-based spiro-isoxazolines: A new family of potent glycogen phosphorylase inhibitors M Benltifa, JM Hayes, S Vidal, D Gueyrard, PG Goekjian, JP Praly, ... Bioorganic & medicinal chemistry 17 (20), 7368-7380, 2009 | 99 | 2009 |
| Amide-1, 2, 3-triazole bioisosterism: the glycogen phosphorylase case ED Chrysina, É Bokor, KM Alexacou, MD Charavgi, GN Oikonomakos, ... Tetrahedron: Asymmetry 20 (6-8), 733-740, 2009 | 97 | 2009 |
| Binding of N‐acetyl‐N ′‐β‐d‐glucopyranosyl urea and N‐benzoyl‐N ′‐β‐d‐glucopyranosyl urea to glycogen phosphorylase b Kinetic and … NG Oikonomakos, M Kosmopoulou, SE Zographos, DD Leonidas, ... European journal of biochemistry 269 (6), 1684-1696, 2002 | 97 | 2002 |
| Role of conserved residues in structure and stability: Tryptophans of human serum retinol‐binding protein, a model for the lipocalin superfamily LH Greene, ED Chrysina, LI Irons, AC Papageorgiou, KR Acharya, ... Protein Science 10 (11), 2301-2316, 2001 | 95 | 2001 |
| Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition D Goyard, B Kónya, AS Chajistamatiou, ED Chrysina, J Leroy, S Balzarin, ... European Journal of Medicinal Chemistry 108, 444-454, 2016 | 92 | 2016 |
| The binding of β‐and γ‐cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studies N Pinotsis, DD Leonidas, ED Chrysina, NG Oikonomakos, IM Mavridis Protein science 12 (9), 1914-1924, 2003 | 85 | 2003 |
| High‐resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure‐based design of ribonucleolytic … DD Leonidas, GB Chavali, NG Oikonomakos, ED Chrysina, ... Protein Science 12 (11), 2559-2574, 2003 | 73 | 2003 |
| Metagenomic mining for thermostable esterolytic enzymes uncovers a new family of bacterial esterases D Zarafeta, D Moschidi, E Ladoukakis, S Gavrilov, ED Chrysina, ... Scientific reports 6 (1), 38886, 2016 | 71 | 2016 |
| Synthesis of variously coupled conjugates of D-glucose, 1, 3, 4-oxadiazole, and 1, 2, 3-triazole for inhibition of glycogen phosphorylase S Kun, GZ Nagy, M Tóth, L Czecze, AN Van Nhien, T Docsa, P Gergely, ... Carbohydrate research 346 (12), 1427-1438, 2011 | 70 | 2011 |
| Structural Studies on Phospho-CDK2/Cyclin A Bound to Nitrate, a Transition State Analogue: Implications for the Protein Kinase Mechanism, A Cook, ED Lowe, ED Chrysina, VT Skamnaki, NG Oikonomakos, ... Biochemistry 41 (23), 7301-7311, 2002 | 67 | 2002 |
| The structure of a novel glucuronoyl esterase from Myceliophthora thermophila gives new insights into its role as a potential biocatalyst MD Charavgi, M Dimarogona, E Topakas, P Christakopoulos, ... Acta Crystallographica Section D: Biological Crystallography 69 (1), 63-73, 2013 | 59 | 2013 |
| Binding of the potential antitumour agent indirubin‐5‐sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b: Comparison with ligand binding to pCDK2–cyclin … MN Kosmopoulou, DD Leonidas, ED Chrysina, N Bischler, G Eisenbrand, ... European Journal of Biochemistry 271 (11), 2280-2290, 2004 | 59 | 2004 |
| Cubic lyotropic liquid crystals as drug delivery carriers: Physicochemical and morphological studies M Chountoulesi, N Pippa, S Pispas, ED Chrysina, A Forys, B Trzebicka, ... International Journal of Pharmaceutics 550 (1-2), 57-70, 2018 | 45 | 2018 |
| Crystallographic and computational studies on 4‐phenyl‐N‐(β‐d‐glucopyranosyl)‐1H‐1, 2, 3‐triazole‐1‐acetamide, an inhibitor of glycogen phosphorylase: Comparison with α‐d … KM Alexacou, JM Hayes, C Tiraidis, SE Zographos, DD Leonidas, ... Proteins: Structure, Function, and Bioinformatics 71 (3), 1307-1323, 2008 | 43 | 2008 |
| A common ‘aggregation‐prone’interface possibly participates in the self‐assembly of human zona pellucida proteins NN Louros, ED Chrysina, GE Baltatzis, ES Patsouris, SJ Hamodrakas, ... FEBS letters 590 (5), 619-630, 2016 | 36 | 2016 |
| Efficient Atropodiastereoselective Access to 5, 5′‐Bis‐1, 2, 3‐triazoles: Studies on 1‐Glucosylated 5‐Halogeno 1, 2, 3‐Triazoles and Their 5‐Substituted Derivatives as … D Goyard, AS Chajistamatiou, AI Sotiropoulou, ED Chrysina, JP Praly, ... Chemistry–A European Journal 20 (18), 5423-5432, 2014 | 36 | 2014 |
Demetres LeonidasProfessor of Biochemistry, Department of Biochemistry and Biotechnology, University of ThessalyVerified email at bio.uth.gr
