| NLRP6 protects Il10−/− mice from colitis by limiting colonization of Akkermansia muciniphila SS Seregin, N Golovchenko, B Schaf, J Chen, NA Pudlo, J Mitchell, ... Cell reports 19 (4), 733-745, 2017 | 338 | 2017 |
| The NLRP6 inflammasome recognizes lipoteichoic acid and regulates gram-positive pathogen infection H Hara, SS Seregin, D Yang, K Fukase, M Chamaillard, ES Alnemri, ... Cell 175 (6), 1651-1664. e14, 2018 | 224 | 2018 |
| Cutting Edge: Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic … I Evnouchidou, RP Kamal, SS Seregin, Y Goto, M Tsujimoto, A Hattori, ... The Journal of Immunology 186 (4), 1909-1913, 2011 | 158 | 2011 |
| Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses E Zervoudi, E Saridakis, JR Birtley, SS Seregin, E Reeves, P Kokkala, ... Proceedings of the National Academy of Sciences 110 (49), 19890-19895, 2013 | 125 | 2013 |
| Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy SS Seregin, DM Appledorn, AJ McBride, NJ Schuldt, YA Aldhamen, ... Molecular Therapy 17 (4), 685-696, 2009 | 111 | 2009 |
| Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors SS Seregin, A Amalfitano Expert opinion on biological therapy 9 (12), 1521-1531, 2009 | 109 | 2009 |
| A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing I Evnouchidou, J Birtley, S Seregin, A Papakyriakou, E Zervoudi, ... The Journal of Immunology 189 (5), 2383-2392, 2012 | 90 | 2012 |
| Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors DM Appledorn, A McBride, S Seregin, JM Scott, N Schuldt, A Kiang, ... Gene therapy 15 (24), 1606-1617, 2008 | 82 | 2008 |
| Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens SS Seregin, DPW Rastall, I Evnouchidou, CF Aylsworth, D Quiroga, ... Autoimmunity 46 (8), 497-508, 2013 | 76 | 2013 |
| NLRP6 function in inflammatory monocytes reduces susceptibility to chemically induced intestinal injury SS Seregin, N Golovchenko, B Schaf, J Chen, KA Eaton, GY Chen Mucosal immunology 10 (2), 434-445, 2017 | 63 | 2017 |
| Wild-type adenoviruses from groups A–F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent DM Appledorn, A Kiang, A McBride, H Jiang, S Seregin, JM Scott, ... Gene therapy 15 (12), 885-901, 2008 | 58 | 2008 |
| Sublingual administration of an adenovirus serotype 5 (Ad5)-based vaccine confirms Toll-like receptor agonist activity in the oral cavity and elicits improved mucosal and … DM Appledorn, YA Aldhamen, S Godbehere, SS Seregin, A Amalfitano Clinical and Vaccine Immunology 18 (1), 150-160, 2011 | 57 | 2011 |
| ELOVL4-mediated production of very long-chain ceramides stabilizes tight junctions and prevents diabetes-induced retinal vascular permeability NM Kady, X Liu, TA Lydic, MH Syed, S Navitskaya, Q Wang, SS Hammer, ... Diabetes 67 (4), 769-781, 2018 | 49 | 2018 |
| Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells YA Aldhamen, Y Pepelyayeva, DPW Rastall, SS Seregin, E Zervoudi, ... Journal of innate immunity 7 (3), 275-289, 2015 | 48 | 2015 |
| Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition T Toubai, H Fujiwara, C Rossi, M Riwes, H Tamaki, C Zajac, C Liu, ... Nature microbiology 4 (5), 800-812, 2019 | 44 | 2019 |
| Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector–triggered immune responses in vitro and in vivo SS Seregin, YA Aldhamen, DM Appledorn, ZC Hartman, NJ Schuldt, ... Blood, The Journal of the American Society of Hematology 116 (10), 1669-1677, 2010 | 44 | 2010 |
| Improving adenovirus based gene transfer: strategies to accomplish immune evasion SS Seregin, A Amalfitano Viruses 2 (9), 2013-2036, 2010 | 43 | 2010 |
| A New Adenovirus Based Vaccine Vector Expressing an Eimeria tenella Derived TLR Agonist Improves Cellular Immune Responses to an Antigenic Target DM Appledorn, YA Aldhamen, W DePas, SS Seregin, CJJ Liu, N Schuldt, ... PLoS One 5 (3), e9579, 2010 | 42 | 2010 |
| Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens YA Aldhamen, DM Appledorn, SS Seregin, CJ Liu, NJ Schuldt, ... The Journal of Immunology 186 (2), 722-732, 2011 | 41 | 2011 |
| Nod1 limits colitis-associated tumorigenesis by regulating IFN-γ production Y Zhan, SS Seregin, J Chen, GY Chen The Journal of Immunology 196 (12), 5121-5129, 2016 | 40 | 2016 |
