David Lutje Hulsik
David Lutje Hulsik
Unknown affiliation
Verified email at lavatherapeutics.com
Cited by
Cited by
Isolation of llama antibody fragments for prevention of dandruff by phage display in shampoo
E Dolk, M Van Der Vaart, DL Hulsik, G Vriend, H de Haard, S Spinelli, ...
Applied and environmental microbiology 71 (1), 442-450, 2005
Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma …
G Bodon, R Chassefeyre, K Pernet-Gallay, N Martinelli, G Effantin, ...
Journal of Biological Chemistry 286 (46), 40276-40286, 2011
Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41
C Sabin, D Corti, V Buzon, MS Seaman, DL Hulsik, A Hinz, F Vanzetta, ...
PLoS pathogens 6 (11), e1001195, 2010
Modular signature and data-capture system and point of transaction payment and reward system
L Fernando, A Rafii, N Williams, EA Bunn, A Valliani
US Patent App. 10/377,830, 2010
Heavier-than-air flying machines are impossible
L Oliveira, T Hulsen, DL Hulsik, ACM Paiva, G Vriend
FEBS letters 564 (3), 269-273, 2004
Llama antibody fragments recognizing various epitopes of the CD4bs neutralize a broad range of HIV-1 subtypes A, B and C
N Strokappe, A Szynol, M Aasa-Chapman, A Gorlani, AF Quigley, ...
PloS one 7 (3), e33298, 2012
A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition
DL Hulsik, Y Liu, NM Strokappe, S Battella, M El Khattabi, LE McCoy, ...
PLoS Pathog 9 (3), e1003202, 2013
Structural basis for ESCRT-III CHMP3 recruitment of AMSH
J Solomons, C Sabin, E Poudevigne, Y Usami, DL Hulsik, P Macheboeuf, ...
Structure 19 (8), 1149-1159, 2011
Characterization of a trimeric MPER containing HIV-1 gp41 antigen
A Hinz, G Schoehn, H Quendler, DL Hulsik, G Stiegler, H Katinger, ...
Virology 390 (2), 221-227, 2009
Crystal Structure of the Neutralizing Llama V HH D7 and Its Mode of HIV-1 gp120 Interaction
A Hinz, DL Hulsik, A Forsman, WWL Koh, H Belrhali, A Gorlani, ...
PloS one 5 (5), e10482, 2010
Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodeling
A De Morrée, DL Hulsik, A Impagliazzo, HH van Haagen, P de Galan, ...
PLoS One 5 (8), e11940, 2010
A fusion intermediate gp41 immunogen elicits neutralizing antibodies to HIV-1
RPJ Lai, M Hock, J Radzimanowski, P Tonks, DL Hulsik, G Effantin, ...
Journal of Biological Chemistry 289 (43), 29912-29926, 2014
Antibody engineering reveals the important role of J segments in the production efficiency of llama single-domain antibodies in Saccharomyces cerevisiae
A Gorlani, D Lutje Hulsik, H Adams, G Vriend, P Hermans, T Verrips
Protein Engineering, Design & Selection 25 (1), 39-46, 2012
Functional characterization of the selective pan-allele anti-SIRPα antibody ADU-1805 that blocks the SIRPα–CD47 innate immune checkpoint
E Voets, M Paradé, DL Hulsik, S Spijkers, W Janssen, J Rens, ...
Journal for immunotherapy of cancer 7 (1), 340, 2019
Improving properties of llama heavy chain antibodies using in silico analysis
D Lutje Hulsik
University Utrecht, 2009
Altered APRIL binding antibodies
H Van Eenennaam, A Van Elsas, DL Hulsik, JP Medema
US Patent 9,969,808, 2018
Development of a first in class APRIL fully blocking antibody BION-1301 for the treatment of multiple myeloma
J Dulos, L Driessen, M Snippert, M Guadagnoli, A Bertens, DL Hulsik, ...
Cancer Res 77 (Suppl 13), 2645, 2017
Development of an agonistic antibody against the human T-cell costimulatory receptor CD27 as a potential immunotherapeutic tool.
H van Eenennaam, E Veraar, W Mulder, E Bastiaanssen, L Driessen, ...
Cancer Research 73 (8 Supplement), 1246-1246, 2013
Vhh for the Diagnosis, Prevention and Treatment of Diseases Associated with Protein Aggregates
CT Verrips, SM Van Der Maarel, P Verheesen, DL Hulsik, ...
US Patent App. 11/992,330, 2010
Stability of llama heavy chain antibody fragments under extreme conditions
E Dolk
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