Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems A Raue, B Steiert, M Schelker, C Kreutz, T Maiwald, H Hass, J Vanlier, ... Bioinformatics 31 (21), 3558-3560, 2015 | 251 | 2015 |
Functional precision medicine provides clinical benefit in advanced aggressive hematologic cancers and identifies exceptional responders C Kornauth, T Pemovska, GI Vladimer, G Bayer, M Bergmann, S Eder, ... Cancer discovery 12 (2), 372-387, 2022 | 88 | 2022 |
Creating functional engineered variants of the single-module non-ribosomal peptide synthetase IndC by T domain exchange R Beer, K Herbst, N Ignatiadis, I Kats, L Adlung, H Meyer, D Niopek, ... Molecular BioSystems 10 (7), 1709-1718, 2014 | 48 | 2014 |
Robustness of DNA repair through collective rate control P Verbruggen, T Heinemann, E Manders, G von Bornstaedt, R van Driel, ... PLoS computational biology 10 (1), e1003438, 2014 | 23 | 2014 |
Modeling chemotherapy-induced stress to identify rational combination therapies in the DNA damage response pathway O Alkan, B Schoeberl, M Shah, A Koshkaryev, T Heinemann, ... Science signaling 11 (540), eaat0229, 2018 | 22 | 2018 |
Model calibration and uncertainty analysis in signaling networks T Heinemann, A Raue Current opinion in biotechnology 39, 143-149, 2016 | 19 | 2016 |
Deep Morphology Learning Enhances Ex Vivo Drug Profiling-Based Precision Medicine T Heinemann, C Kornauth, Y Severin, GI Vladimer, T Pemovska, ... Blood Cancer Discovery 3 (6), 502-515, 2022 | 11 | 2022 |
TIN− a combinatorial compound collection of synthetically feasible multicomponent synthesis products KV Dorschner, D Toomey, MP Brennan, T Heinemann, FJ Duffy, KB Nolan, ... Journal of chemical information and modeling 51 (5), 986-995, 2011 | 9 | 2011 |
Treatment Guided By Next Generation Functional Drug Screening Provides Clinical Benefit in Advanced Aggressive Hematological Malignancies: Final Evaluation of the Open Label … C Kornauth, T Pemovska, GI Vladimer, G Bayer, M Bergmann, S Eder, ... Blood 136, 2-4, 2020 | 1 | 2020 |
S134: INTRA-PATIENT FUNCTIONAL HETEROGENEITY OF AML DETERMINES FIRST-LINE TREATMENT RESPONSE Y Severin, Y Festl, M Roiss, T Benoit, T Heinemann, R Wegmann, ... HemaSphere 6, 35-36, 2022 | | 2022 |
Understanding chemotherapy-induced replicative stress to identify rational combination therapies O Alkan, B Schoeberl, M Shah, A Koshkaryev, T Heinemann, ... Cancer Research 78 (13), 2018 | | 2018 |
Non-ribosomal protein synthesis pigment fusion peptides R Eils, B Di Ventura, L Adlung, K Genreith, T Heinemann, H Meyer, ... US Patent App. 15/026,734, 2016 | | 2016 |
BBF RFC 99: HiCT: High Throughput Protocols For CPE Cloning And Transformation R Beer, T Christiansen, K Herbst, N Ignatiadis, I Kats, N Kurzawa, ... | | 2013 |
Standard for Synthesis of Customized Peptides by Non-Ribosomal Peptide Synthetases R Beer, T Christiansen, K Herbst, N Ignatiadis, I Kats, N Kurzawa, ... | | 2013 |
HiCT: High Throughput Protocols For CPE Cloning And Transformation R Beer, T Christiansen, K Herbst, N Ignatiadis, I Kats, N Kurzawa, ... | | 2013 |
Model-guided random assembly pcr for the synthesis of eukaryotic promoters Y Reis, D Richter, M Reichenzeller, N Iwamoto, C Zhu, H Uckelmann, ... | | 2011 |
Design of Specific Mammalian Promoters by in silico Prediction T Heinemann, S Kramer, L Velten, AL Kranz, T Bauer, MB Faura, R Konig, ... | | 2009 |
SUPPLEMENTARY INFORMATION Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems A Raue, B Steiert, M Schelker, C Kreutz, T Maiwald, H Hass, J Vanlier, ... | | |