The bone marrow functionally contributes to liver fibrosis FP Russo, MR Alison, BW Bigger, E Amofah, A Florou, F Amin, ... Gastroenterology 130 (6), 1807-1821, 2006 | 683 | 2006 |
Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse QL Lu, CJ Mann, F Lou, G Bou-Gharios, GE Morris, S Xue, S Fletcher, ... Nature medicine 9 (8), 1009-1014, 2003 | 594 | 2003 |
Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles QL Lu, A Rabinowitz, YC Chen, T Yokota, HF Yin, J Alter, A Jadoon, ... Proceedings of the National Academy of Sciences 102 (1), 198-203, 2005 | 493 | 2005 |
Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile … X Shi-Wen, Y Chen, CP Denton, M Eastwood, EA Renzoni, ... Molecular biology of the cell 15 (6), 2707-2719, 2004 | 459 | 2004 |
Fibroblast matrix gene expression and connective tissue remodeling: role of endothelin-1 X Shi-wen, CP Denton, AM Holmes, CM Black, DJ Abraham, ... Journal of Investigative Dermatology 116 (3), 417-425, 2001 | 343 | 2001 |
Pivotal role of connective tissue growth factor in lung fibrosis: MAPK‐dependent transcriptional activation of type I collagen M Ponticos, AM Holmes, X Shi‐Wen, P Leoni, K Khan, VS Rajkumar, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 282 | 2009 |
Non-viral gene delivery in skeletal muscle: a protein factory QL Lu, G Bou-Gharios, TA Partridge Gene therapy 10 (2), 131-142, 2003 | 246 | 2003 |
Bone marrow‐derived myofibroblasts contribute functionally to scar formation after myocardial infarction MJ Van Amerongen, G Bou‐Gharios, ER Popa, J Van Ark, AH Petersen, ... The Journal of pathology 214 (3), 377-386, 2008 | 245 | 2008 |
Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis S Sonnylal, X Shi‐Wen, P Leoni, K Naff, CS Van Pelt, H Nakamura, ... Arthritis & Rheumatism 62 (5), 1523-1532, 2010 | 241 | 2010 |
Platelet-derived growth factor-â receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing VS Rajkumar, X Shiwen, M Bostrom, P Leoni, J Muddle, M Ivarsson, ... The American journal of pathology 169 (6), 2254-2265, 2006 | 232 | 2006 |
Endothelin is a downstream mediator of profibrotic responses to transforming growth factor â in human lung fibroblasts X Shi‐wen, L Kennedy, EA Renzoni, G Bou‐Gharios, RM du Bois, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2007 | 225 | 2007 |
Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice PV Guillot, O Abass, JHD Bassett, SJ Shefelbine, G Bou-Gharios, J Chan, ... Blood, The Journal of the American Society of Hematology 111 (3), 1717-1725, 2008 | 220 | 2008 |
Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK X Shi-wen, SL Howat, EA Renzoni, A Holmes, JD Pearson, ... Journal of Biological Chemistry 279 (22), 23098-23103, 2004 | 220 | 2004 |
Implication of the satellite cell in dystrophic muscle fibrosis: a self-perpetuating mechanism of collagen overproduction C Alexakis, T Partridge, G Bou-Gharios American Journal of Physiology-Cell Physiology 293 (2), C661-C669, 2007 | 209 | 2007 |
CCN2 is necessary for adhesive responses to transforming growth factor-â1 in embryonic fibroblasts X Shi-wen, LA Stanton, L Kennedy, D Pala, Y Chen, SL Howat, ... Journal of Biological Chemistry 281 (16), 10715-10726, 2006 | 209 | 2006 |
Gene expression profiling reveals novel TGFâ targets in adult lung fibroblasts EA Renzoni, DJ Abraham, S Howat, X Shi-Wen, P Sestini, G Bou-Gharios, ... Respiratory research 5, 1-12, 2004 | 174 | 2004 |
A potent far-upstream enhancer in the mouse pro alpha 2 (I) collagen gene regulates expression of reporter genes in transgenic mice. G Bou-Gharios, LA Garrett, J Rossert, K Niederreither, H Eberspaecher, ... The Journal of cell biology 134 (5), 1333-1344, 1996 | 171 | 1996 |
TGF-b signaling in cartilage homeostasis and osteoarthritis KW Finnson, Y Chi, G Bou-Gharios, A Leask, A Philip Front Biosci (Schol Ed) 4 (2), 251e68, 2012 | 169 | 2012 |
Matrix contraction by dermal fibroblasts requires transforming growth factor-â/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into … Y Chen, X Shi-Wen, J van Beek, L Kennedy, M McLeod, EA Renzoni, ... The American journal of pathology 167 (6), 1699-1711, 2005 | 159 | 2005 |
Extra‐cellular matrix in vascular networks G Bou‐Gharios, M Ponticos, V Rajkumar, D Abraham Cell proliferation 37 (3), 207-220, 2004 | 158 | 2004 |