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VARUN SASIDHARAN NAIR
VARUN SASIDHARAN NAIR
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα iit.it
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Immune checkpoint inhibitors: recent progress and potential biomarkers
P Darvin, SM Toor, VS Nair, E Elkord
Experimental & molecular medicine 50 (12), 1-11, 2018
18492018
Immune checkpoint inhibitors in cancer therapy: a focus on T‐regulatory cells
V Sasidharan Nair, E Elkord
Immunology and cell biology 96 (1), 21-33, 2018
2862018
T‐cell responses and therapies against SARS‐CoV‐2 infection
SM Toor, R Saleh, V Sasidharan Nair, RZ Taha, E Elkord
Immunology 162 (1), 30-43, 2021
2002021
Immune Checkpoints in the Tumor Microenvironment
SM Toor, VS Nair, J Decock, E Elkord
Semin Cancer Biology, 2019
1802019
Vitamin C facilitates demethylation of the Foxp3 enhancer in a Tet-dependent manner
V Sasidharan Nair, MH Song, KI Oh
The journal of immunology 196 (5), 2119-2131, 2016
1702016
DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer
V Sasidharan Nair, H El Salhat, RZ Taha, A John, BR Ali, E Elkord
Clinical epigenetics 10, 1-12, 2018
1232018
Dual inhibition of STAT1 and STAT3 activation downregulates expression of PD-L1 in human breast cancer cells
V Sasidharan Nair, SM Toor, BR Ali, E Elkord
Expert opinion on therapeutic targets 22 (6), 547-557, 2018
1032018
Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer
R Saleh, RZ Taha, SM Toor, V Sasidharan Nair, K Murshed, M Khawar, ...
Cancer Immunology, Immunotherapy 69, 1989-1999, 2020
912020
DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer
V Sasidharan Nair, SM Toor, RZ Taha, H Shaath, E Elkord
Clinical epigenetics 10, 1-9, 2018
852018
Role of epigenetic modifications in inhibitory immune checkpoints in cancer development and progression
R Saleh, SM Toor, V Sasidharan Nair, E Elkord
Frontiers in immunology 11, 544793, 2020
672020
PD-L1 blockade by atezolizumab downregulates signaling pathways associated with tumor growth, metastasis, and hypoxia in human triple negative breast cancer
R Saleh, RZ Taha, V Sasidharan Nair, NM Alajez, E Elkord
Cancers 11 (8), 1050, 2019
672019
DNA demethylation of the Foxp3 enhancer is maintained through modulation of ten-eleven-translocation and DNA methyltransferases
VS Nair, MH Song, M Ko, KI Oh
Molecules and cells 39 (12), 888-897, 2016
652016
DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients
AA Elashi, V Sasidharan Nair, RZ Taha, H Shaath, E Elkord
Oncoimmunology 8 (2), e1542918, 2019
562019
PD-L1 expression in human breast cancer stem cells is epigenetically regulated through posttranslational histone modifications
P Darvin, V Sasidharan Nair, E Elkord
Journal of oncology 2019, 2019
552019
Vitamin C enhances the expression of IL17 in a Jmjd2–dependent manner
MH Song, VS Nair, KI Oh
BMB reports 50 (1), 49, 2017
532017
Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer
V Sasidharan Nair, R Saleh, SM Toor, RZ Taha, AA Ahmed, MA Kurer, ...
Clinical epigenetics 12, 1-15, 2020
522020
Down-regulation of Tet2 prevents TSDR demethylation in IL2 deficient regulatory T cells
VS Nair, KI Oh
Biochemical and biophysical research communications 450 (1), 918-924, 2014
522014
Integrated transcriptome and pathway analyses revealed multiple activated pathways in breast cancer
R Vishnubalaji, V Sasidharan Nair, K Ouararhni, E Elkord, NM Alajez
Frontiers in oncology 9, 910, 2019
372019
Transcriptomic analyses revealed systemic alterations in gene expression in circulation and tumor microenvironment of colorectal cancer patients
H Shaath, S Toor, VS Nair, E Elkord, NM Alajez
Cancers 11 (12), 1994, 2019
332019
Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment
V Sasidharan Nair, R Saleh, SM Toor, FS Cyprian, E Elkord
Cancer immunology, immunotherapy 70, 2103-2121, 2021
272021
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