Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions D Zhou, LR Palam, L Jiang, J Narasimhan, KA Staschke, RC Wek Journal of Biological Chemistry 283 (11), 7064-7073, 2008 | 344 | 2008 |
Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response S Dey, TD Baird, D Zhou, LR Palam, DF Spandau, RC Wek Journal of Biological Chemistry 285 (43), 33165-33174, 2010 | 275 | 2010 |
CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis BF Teske, ME Fusakio, D Zhou, J Shan, JN McClintick, MS Kilberg, ... Molecular biology of the cell 24 (15), 2477-2490, 2013 | 232 | 2013 |
Small-molecule covalent modification of conserved cysteine leads to allosteric inhibition of the TEAD⋅ Yap protein-protein interaction K Bum-Erdene, D Zhou, G Gonzalez-Gutierrez, MK Ghozayel, Y Si, D Xu, ... Cell chemical biology 26 (3), 378-389. e13, 2019 | 146 | 2019 |
Mechanisms of translational regulation by a human eIF5-mimic protein CR Singh, R Watanabe, D Zhou, MD Jennings, A Fukao, B Lee, Y Ikeda, ... Nucleic acids research 39 (19), 8314-8328, 2011 | 57 | 2011 |
A new class of orthosteric uPAR· uPA small-molecule antagonists are allosteric inhibitors of the uPAR· vitronectin interaction D Liu, D Zhou, B Wang, WE Knabe, SO Meroueh ACS chemical biology 10 (6), 1521-1534, 2015 | 28 | 2015 |
Small-molecule CaVα1⋅ CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking X Chen, D Liu, D Zhou, Y Si, D Xu, CW Stamatkin, MK Ghozayel, ... Proceedings of the National Academy of Sciences 115 (45), E10566-E10575, 2018 | 26 | 2018 |
Probing binding and cellular activity of pyrrolidinone and piperidinone small molecules targeting the urokinase receptor T Mani, D Liu, D Zhou, L Li, WE Knabe, F Wang, K Oh, SO Meroueh ChemMedChem 8 (12), 1963-1977, 2013 | 25 | 2013 |
Small molecules engage hot spots through cooperative binding to inhibit a tight protein–protein interaction D Liu, D Xu, M Liu, WE Knabe, C Yuan, D Zhou, M Huang, SO Meroueh Biochemistry 56 (12), 1768-1784, 2017 | 20 | 2017 |
Mimicking Intermolecular Interactions of Tight Protein–Protein Complexes for Small‐Molecule Antagonists D Xu, K Bum‐Erdene, Y Si, D Zhou, MK Ghozayel, SO Meroueh ChemMedChem 12 (21), 1794-1809, 2017 | 15 | 2017 |
Small molecules inhibit STAT3 activation, autophagy, and cancer cell anchorage-independent growth D Zhou, MZ Springer, D Xu, D Liu, A Hudmon, KF Macleod, SO Meroueh Bioorganic & medicinal chemistry 25 (12), 2995-3005, 2017 | 10 | 2017 |
Structure‐based target‐specific screening leads to small‐molecule CaMKII inhibitors D Xu, L Li, D Zhou, D Liu, A Hudmon, SO Meroueh ChemMedChem 12 (9), 660-677, 2017 | 9 | 2017 |
Anti-tumor effects of an engineered “killer” transfer RNA D Zhou, J Lee, C Frankenberger, R Geslain, M Rosner, T Pan Biochemical and Biophysical Research Communications 427 (1), 148-153, 2012 | 9 | 2012 |
Phenotypic screening of chemical libraries enriched by molecular docking to multiple targets selected from glioblastoma genomic data D Xu, D Zhou, K Bum-Erdene, BJ Bailey, K Sishtla, S Liu, J Wan, UK Aryal, ... ACS chemical biology 15 (6), 1424-1444, 2020 | 4 | 2020 |
Small molecules inhibit ex vivo tumor growth in bone D Zhou, K Bum-Erdene, D Xu, D Liu, D Tompkins, RS Sulaiman, ... Bioorganic & Medicinal Chemistry 26 (23-24), 6128-6134, 2018 | 3 | 2018 |
Mimicking Native Interactions for Small-Molecule Inhibitors of Tight Protein-Protein Interactions D Xu, K Bum-Erdene, Y Si, D Zhou, D Liu, M Ghozayel, S Meroueh Journal of chemical information and modeling 57 (9), 2250, 2017 | | 2017 |
Astabiotics: Antimicrobial Signal Transduction Activators KR Fortney, A Krieger, L Chen, ZY Zhang, KE Pollok, AJ Wolfe, D Zhou, ... Office of the Vice Chancellor for Research, 2013 | | 2013 |
tRNA and its Activation Targets as Biomarkers and Regulators of Breast Cancer M Rosner, T Pan, MP Eternod, D Zhou, S Gomes, CHICAGO UNIV IL | | 2011 |
tRNAs as therapeutic agents of breast cancer T Pan, CHICAGO UNIV IL | | 2011 |
The mechanisms regulating the transcription factor atf5 and its function in the integrated stress response D Zhou Indiana University, 2010 | | 2010 |