Παρακολούθηση
Jamel Meslamani
Jamel Meslamani
Treeline Biosciences
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα treeline.bio - Αρχική σελίδα
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Παρατίθεται από
Παρατίθεται από
Έτος
The bromodomain: from epigenome reader to druggable target
R Sanchez, J Meslamani, MM Zhou
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (8), 676-685, 2014
2272014
Protein–ligand-based pharmacophores: generation and utility assessment in computational ligand profiling
J Meslamani, J Li, J Sutter, A Stevens, HO Bertrand, D Rognan
Journal of chemical information and modeling 52 (4), 943-955, 2012
1212012
sc-PDB: a database for identifying variations and multiplicity of ‘druggable’binding sites in proteins
J Meslamani, D Rognan, E Kellenberger
Bioinformatics 27 (9), 1324-1326, 2011
1202011
BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice
Proceedings of the National Academy of Sciences, 2017
1042017
Structure–activity relationship studies for enhancer of zeste homologue 2 (EZH2) and enhancer of zeste homologue 1 (EZH1) inhibitors
X Yang, F Li, KD Konze, J Meslamani, A Ma, PJ Brown, MM Zhou, ...
Journal of medicinal chemistry 59 (16), 7617-7633, 2016
552016
Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth
C Ren, G Zhang, F Han, S Fu, Y Cao, F Zhang, Q Zhang, J Meslamani, ...
Proceedings of the National Academy of Sciences 115 (31), 7949-7954, 2018
542018
BRADSHAW: a system for automated molecular design
DVS Green, S Pickett, C Luscombe, S Senger, D Marcus, J Meslamani, ...
Journal of computer-aided molecular design 34, 747-765, 2020
472020
Enhancing the accuracy of chemogenomic models with a three-dimensional binding site kernel
J Meslamani, D Rognan
Journal of chemical information and modeling 51 (7), 1593-1603, 2011
462011
Discovery and lead-optimization of 4, 5-dihydropyrazoles as mono-kinase selective, orally bioavailable and efficacious inhibitors of receptor interacting protein 1 (RIP1) kinase
PA Harris, N Faucher, N George, PM Eidam, BW King, GV White, ...
Journal of Medicinal Chemistry 62 (10), 5096-5110, 2019
402019
Computational profiling of bioactive compounds using a target-dependent composite workflow
J Meslamani, R Bhajun, F Martz, D Rognan
Journal of chemical information and modeling 53 (9), 2322-2333, 2013
372013
Structural features and inhibitors of bromodomains
J Meslamani, SG Smith, R Sanchez, MM Zhou
Drug Discovery Today: Technologies 19, 3-15, 2016
362016
ChEpiMod: a knowledgebase for chemical modulators of epigenome reader domains
J Meslamani, SG Smith, R Sanchez, MM Zhou
Bioinformatics 30 (10), 1481-1483, 2014
182014
Assessing the geometric diversity of cytochrome P450 ligand conformers by hierarchical clustering with a stop criterion
JE Meslamani, F André, M Petitjean
Journal of chemical information and modeling 49 (2), 330-337, 2009
142009
Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin
N Liu, T Konuma, R Sharma, D Wang, N Zhao, L Cao, Y Ju, D Liu, ...
Molecular Cell 83 (13), 2206-2221. e11, 2023
82023
Protein-Ligand Pharmacophores: Concept, Design and Applications
J Meslamani, D Rognan
CICSJ Bulletin, Chemical Information and Computer Science 33 (2), 27, 2015
72015
HIPK2 directs cell type–specific regulation of STAT3 transcriptional activity in Th17 cell differentiation
KL Cheung, A Jaganathan, Y Hu, F Xu, A Lejeune, R Sharma, CI Caescu, ...
Proceedings of the National Academy of Sciences 119 (14), e2117112119, 2022
42022
Développement de nouvelles méthodes de criblage in silico en chémogénomique
JE Meslamani
Strasbourg, 2012
22012
BRADSHAW: a system for automated molecular design (10.1007/s10822-019-00234-8, 2019)
DVS Green, S Pickett, C Luscombe, S Senger, D Marcus, J Meslamani, ...
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN 34 (7), 767-767, 2020
2020
New bromodomain inhibitors with halogen bonding interactions
A Vincek, E Rusinova, J Meslamani, A Plotnikov, T Zhou, M Ohlmeyer, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
Binding affinity prediction using frequency of protein-ligand interactions: method validation and application to bromodomain inhibitors
J Meslamani, AS Vincek, E Russinova, AN Plotnikov, R Sanchez, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
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