|Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions|
JP Shen, D Zhao, R Sasik, J Luebeck, A Birmingham, ...
Nature methods 14 (6), 573-576, 2017
|An enhanced CRISPR repressor for targeted mammalian gene regulation|
NC Yeo, A Chavez, A Lance-Byrne, Y Chan, D Menn, D Milanova, ...
Nature methods 15 (8), 611-616, 2018
|The emerging role of systems biology for engineering protein production in CHO cells|
CC Kuo, AWT Chiang, I Shamie, M Samoudi, JM Gutierrez, NE Lewis
Current opinion in biotechnology 51, 64-69, 2018
|Increasing consensus of context-specific metabolic models by integrating data-inferred cell functions|
A Richelle, AWT Chiang, CC Kuo, NE Lewis
PLoS computational biology 15 (4), e1006867, 2019
|Modulating carbohydrate–protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology|
AWT Chiang, S Li, PN Spahn, A Richelle, CC Kuo, M Samoudi, NE Lewis
Current opinion in structural biology 40, 104-111, 2016
|The human secretome–the proteins secreted from human cells|
M Uhlen, H Tegel, Å Sivertsson, CC Kuo, JM Gutierrez, NE Lewis, ...
BioRxiv, 465815, 2018
|Combating viral contaminants in CHO cells by engineering innate immunity|
AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ...
Scientific reports 9 (1), 1-15, 2019
|Increased mAb production in amplified CHO cell lines is associated with increased interaction of CREB1 with transgene promoter|
H Dahodwala, P Kaushik, V Tejwani, CC Kuo, P Menard, M Henry, ...
Current research in biotechnology 1, 49-57, 2019
|Dysregulation of the secretory pathway connects Alzheimer's disease genetics to aggregate formation|
CC Kuo, WT Chiang, NE Lewis
|A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis|
LY Hsieh, AWT Chiang, LD Duong, CC Kuo, SX Dong, R Dohil, R Kurten, ...
Journal of Allergy and Clinical Immunology, 2021
|In situ detection of protein interactions for recombinant therapeutic enzymes|
M Samoudi*, CC Kuo*, CM Robinson*, K Shams‐Ud‐Doha, SM Schinn, ...
Biotechnology and Bioengineering, 2020
|Restoration of deficient DNA Repair Genes Mitigates Genome Instability and Increases Productivity of Chinese Hamster Ovary Cells|
P Spahn, X Zhang, Q Hu, N Hamaker, H Hefzi, S Li, CC Kuo, Y Huang, ...
bioRxiv, 2021.01. 07.425558, 0