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Haobin Ye
Haobin Ye
Verified email at ucdenver.edu
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Year
Leukemic stem cells evade chemotherapy by metabolic adaptation to an adipose tissue niche
H Ye, B Adane, N Khan, T Sullivan, M Minhajuddin, M Gasparetto, ...
Cell stem cell 19 (1), 23-37, 2016
4782016
Inhibition of amino acid metabolism selectively targets human leukemia stem cells
CL Jones, BM Stevens, A D'Alessandro, JA Reisz, R Culp-Hill, T Nemkov, ...
Cancer cell 34 (5), 724-740. e4, 2018
4512018
Monocytic subclones confer resistance to venetoclax-based therapy in patients with acute myeloid leukemia
S Pei, DA Pollyea, A Gustafson, BM Stevens, M Minhajuddin, R Fu, ...
Cancer discovery 10 (4), 536-551, 2020
3032020
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells
S Pei, M Minhajuddin, KP Callahan, M Balys, JM Ashton, SJ Neering, ...
Journal of Biological Chemistry 288 (47), 33542-33558, 2013
2132013
Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells
BM Stevens, CL Jones, DA Pollyea, R Culp-Hill, A D’Alessandro, ...
Nature cancer 1 (12), 1176-1187, 2020
1802020
Nicotinamide metabolism mediates resistance to venetoclax in relapsed acute myeloid leukemia stem cells
CL Jones, BM Stevens, DA Pollyea, R Culp-Hill, JA Reisz, T Nemkov, ...
Cell stem cell 27 (5), 748-764. e4, 2020
1552020
Subversion of systemic glucose metabolism as a mechanism to support the growth of leukemia cells
H Ye, B Adane, N Khan, E Alexeev, N Nusbacher, M Minhajuddin, ...
Cancer cell 34 (4), 659-673. e6, 2018
1102018
The hematopoietic oxidase NOX2 regulates self-renewal of leukemic stem cells
B Adane, H Ye, N Khan, S Pei, M Minhajuddin, BM Stevens, CL Jones, ...
Cell reports 27 (1), 238-254. e6, 2019
732019
The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation
ML Amaya, A Inguva, S Pei, C Jones, A Krug, H Ye, M Minhajuddin, ...
Blood, The Journal of the American Society of Hematology 139 (4), 584-596, 2022
632022
Repressing malic enzyme 1 redirects glucose metabolism, unbalances the redox state, and attenuates migratory and invasive abilities in nasopharyngeal carcinoma cell lines
FJ Zheng, HB Ye, MS Wu, YF Lian, CN Qian, YX Zeng
Chinese journal of cancer 31 (11), 519, 2012
572012
Inhibition of amino acid metabolism selectively targets human leukemia stem cells
CL Jones, BM Stevens, A D’Alessandro, JA Reisz, R Culp-Hill, T Nemkov, ...
Cancer Cell 35 (2), 333-335, 2019
482019
The hepatic microenvironment uniquely protects leukemia cells through induction of growth and survival pathways mediated by LIPG
H Ye, M Minhajuddin, A Krug, S Pei, CH Chou, R Culp-Hill, J Ponder, ...
Cancer discovery 11 (2), 500-519, 2021
172021
Adipose tissue functions as a reservoir for leukemia stem cells and confers chemo-resistance
H Ye, B Adane, N Khan, JM Ashton, M Balys, BM Stevens, M Minhajuddin, ...
Blood 126 (23), 845, 2015
32015
Developmental plasticity of acute myeloid leukemia mediates resistance to venetoclax-based therapy
S Pei, DA Pollyea, A Gustafson, M Minhajuddin, BM Stevens, H Ye, ...
Blood 134, 185, 2019
22019
Lysosomal Acid Lipase a (LIPA) Modulates Leukemia Stem Cell (LSC) Response to Venetoclax/TKI Combination Therapy in Blast Phase Chronic Myeloid Leukemia
M Minhajuddin, H Ye, AC Winters, S Pei, N Khan, BM Stevens, B Adane, ...
Blood 138, 630, 2021
2021
Cysteine and Cystine Depletion Targets Leukemia Stem Cells
CL Jones, BM Stevens, A D'Alessandro, R Culp-Hill, J Reisz, H Ye, ...
Blood 132, 431, 2018
2018
Adipose Tissue-Derived IGFBP1 Facilitates Progression of Leukemia
H Ye, N Khan, M Minhajuddin, B Adane, CT Jordan
Blood 128 (22), 3058, 2016
2016
The Role of NADPH Oxidase 2 in Normal and Malignant Hematopoiesis
B Adane, H Ye, S Pei, N Khan, M Minhajuddin, BM Stevens, ...
Blood 128 (22), 1079, 2016
2016
Leukemia Cells Resident in Adipose Tissue Display a Pro-Inflammatory Phenotype and Induce Lipolysis and Atrophy of Adipose Tissue
H Ye, N Khan, M Balys, JM Ashton, B Adane, CT Jordan
Blood 126 (23), 2765, 2015
2015
Unique Physiological and Metabolic Properties of Blast Crisis Chronic Myeloid Leukemia
H Ye
2015
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