Azra H. Ligon, PhD, FACMG
Azra H. Ligon, PhD, FACMG
Brigham & Women's Hospital/Harvard Medical School
Verified email at
Cited by
Cited by
The landscape of somatic copy-number alteration across human cancers
R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ...
Nature 463 (7283), 899-905, 2010
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
PA Steck, MA Pershouse, SA Jasser, WKA Yung, H Lin, AH Ligon, ...
Nature genetics 15 (4), 356-362, 1997
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma
SM Ansell, AM Lesokhin, I Borrello, A Halwani, EC Scott, M Gutierrez, ...
New England Journal of Medicine 372 (4), 311-319, 2015
Recurrent BRAF mutations in Langerhans cell histiocytosis
G Badalian-Very, JA Vergilio, BA Degar, LE MacConaill, B Brandner, ...
Blood, The Journal of the American Society of Hematology 116 (11), 1919-1923, 2010
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
JW Locasale, AR Grassian, T Melman, CA Lyssiotis, KR Mattaini, AJ Bass, ...
Nature genetics 43 (9), 869-874, 2011
Nivolumab in patients with relapsed or refractory hematologic malignancy: preliminary results of a phase Ib study
AM Lesokhin, SM Ansell, P Armand, EC Scott, A Halwani, M Gutierrez, ...
Journal of clinical oncology 34 (23), 2698-2704, 2016
Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial
A Younes, A Santoro, M Shipp, PL Zinzani, JM Timmerman, S Ansell, ...
The lancet oncology 17 (9), 1283-1294, 2016
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
YJ Cho, A Tsherniak, P Tamayo, S Santagata, A Ligon, H Greulich, ...
Journal of clinical oncology 29 (11), 1424, 2011
CDK8 is a colorectal cancer oncogene that regulates -catenin activity
R Firestein, AJ Bass, SY Kim, IF Dunn, SJ Silver, I Guney, E Freed, ...
Nature 455 (7212), 547-551, 2008
PD-L1 and PD-L2 genetic alterations define classical Hodgkin lymphoma and predict outcome
MGM Roemer, RH Advani, AH Ligon, Y Natkunam, RA Redd, H Homer, ...
Journal of Clinical Oncology 34 (23), 2690, 2016
Focal gains of VEGFA and molecular classification of hepatocellular carcinoma
DY Chiang, A Villanueva, Y Hoshida, J Peix, P Newell, B Minguez, ...
Cancer research 68 (16), 6779-6788, 2008
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
U Schüller, VM Heine, J Mao, AT Kho, AK Dillon, YG Han, E Huillard, ...
Cancer cell 14 (2), 123-134, 2008
Targetable genetic features of primary testicular and primary central nervous system lymphomas
B Chapuy, MGM Roemer, C Stewart, Y Tan, RP Abo, L Zhang, AJ Dunford, ...
Blood, The Journal of the American Society of Hematology 127 (7), 869-881, 2016
Mechanisms and therapeutic implications of hypermutation in gliomas
M Touat, YY Li, AN Boynton, LF Spurr, JB Iorgulescu, CL Bohrson, ...
Nature 580 (7804), 517-523, 2020
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma
AM Fontebasso, S Papillon-Cavanagh, J Schwartzentruber, H Nikbakht, ...
Nature genetics 46 (5), 462-466, 2014
Clinical activity of mTOR inhibition with sirolimus in malignant perivascular epithelioid cell tumors: targeting the pathogenic activation of mTORC1 in tumors
AJ Wagner, I Malinowska-Kolodziej, JA Morgan, W Qin, CDM Fletcher, ...
Journal of clinical oncology 28 (5), 835, 2010
Validation of OncoPanel: a targeted next-generation sequencing assay for the detection of somatic variants in cancer
EP Garcia, A Minkovsky, Y Jia, MD Ducar, P Shivdasani, X Gong, ...
Archives of Pathology and Laboratory Medicine 141 (6), 751-758, 2017
Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial
J Fangusaro, A Onar-Thomas, TY Poussaint, S Wu, AH Ligon, ...
The lancet oncology 20 (7), 1011-1022, 2019
Integration of cytogenetic landmarks into the draft sequence of the human genome
T BAC Resource Consortium, VG Cheung, N Nowak, W Jang, IR Kirsch, ...
Nature 409 (6822), 953-958, 2001
Institutional implementation of clinical tumor profiling on an unselected cancer population
LM Sholl, K Do, P Shivdasani, E Cerami, AM Dubuc, FC Kuo, EP Garcia, ...
JCI insight 1 (19), 2016
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