| The analgesic-like properties of the alpha7 nAChR silent agonist NS6740 is associated with non-conducting conformations of the receptor RL Papke, D Bagdas, AR Kulkarni, T Gould, SD AlSharari, GA Thakur, ... Neuropharmacology 91, 34-42, 2015 | 97 | 2015 |
| The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain D Bagdas, JL Wilkerson, A Kulkarni, W Toma, S AlSharari, Z Gul, ... British Journal of Pharmacology 173 (16), 2506-2520, 2016 | 78 | 2016 |
| Expeditious Synthesis, Enantiomeric Resolution, and Enantiomer Functional Characterization of (4-(4-Bromophenyl)-3a, 4, 5, 9b-tetrahydro-3 H-cyclopenta [c] quinoline-8 … GA Thakur, AR Kulkarni, JR Deschamps, RL Papke Journal of medicinal chemistry 56 (21), 8943-8947, 2013 | 75 | 2013 |
| Novel electrophilic and photoaffinity covalent probes for mapping the cannabinoid 1 receptor allosteric site (s) PM Kulkarni, AR Kulkarni, A Korde, RB Tichkule, RB Laprairie, ... Journal of medicinal chemistry 59 (1), 44-60, 2016 | 65 | 2016 |
| Scalable, one-pot, microwave-accelerated tandem synthesis of unsymmetrical urea derivatives AR Kulkarni, S Garai, GA Thakur The Journal of organic chemistry 82 (2), 992-999, 2017 | 54 | 2017 |
| Critical molecular determinants of α7 nicotinic acetylcholine receptor allosteric activation: separation of direct allosteric activation and positive allosteric modulation NA Horenstein, RL Papke, AR Kulkarni, GU Chaturbhuj, C Stokes, ... Journal of Biological Chemistry 291 (10), 5049-5067, 2016 | 53 | 2016 |
| The activity of GAT107, an allosteric activator and positive modulator of α7 nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the … RL Papke, NA Horenstein, AR Kulkarni, C Stokes, LW Corrie, CY Maeng, ... Journal of Biological Chemistry 289 (7), 4515-4531, 2014 | 45 | 2014 |
| Microwave-assisted expeditious and efficient synthesis of cyclopentene ring-fused tetrahydroquinoline derivatives using three-component povarov reaction AR Kulkarni, GA Thakur Tetrahedron letters 54 (48), 6592-6595, 2013 | 43 | 2013 |
| Mapping cannabinoid 1 receptor allosteric site (s): critical molecular determinant and signaling profile of GAT100, a novel, potent, and irreversibly binding probe RB Laprairie, AR Kulkarni, PM Kulkarni, DP Hurst, D Lynch, PH Reggio, ... ACS chemical neuroscience 7 (6), 776-798, 2016 | 37 | 2016 |
| Persistent activation of α7 nicotinic ACh receptors associated with stable induction of different desensitized states RL Papke, C Stokes, MI Damaj, GA Thakur, K Manther, M Treinin, ... British Journal of Pharmacology 175 (11), 1838-1854, 2018 | 35 | 2018 |
| The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice G Donvito, D Bagdas, W Toma, E Rahimpour, A Jackson, JA Meade, ... Experimental neurology 295, 194-201, 2017 | 29 | 2017 |
| The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal W Toma, SL Kyte, D Bagdas, A Jackson, JA Meade, F Rahman, ZJ Chen, ... Experimental neurology 320, 113010, 2019 | 26 | 2019 |
| Targeting of micelles and liposomes loaded with the pro-apoptotic drug, NCL-240, into NCI/ADR-RES cells in a 3D spheroid model BS Pattni, SG Nagelli, B Aryasomayajula, PP Deshpande, A Kulkarni, ... Pharmaceutical research 33, 2540-2551, 2016 | 18 | 2016 |
| Combination Nanopreparations of a Novel Proapoptotic Drug–NCL-240, TRAIL and siRNA R Riehle, B Pattni, A Jhaveri, A Kulkarni, G Thakur, A Degterev, ... Pharmaceutical research 33, 1587-1601, 2016 | 17 | 2016 |
| Design and synthesis of cannabinoid 1 receptor (CB1R) allosteric modulators: drug discovery applications AR Kulkarni, S Garai, DR Janero, GA Thakur Methods in Enzymology 593, 281-315, 2017 | 15 | 2017 |
| RIC3, the cholinergic anti-inflammatory pathway, and neuroinflammation Y Ben-David, S Kagan, HC Ben-Ami, J Rostami, T Mizrahi, AR Kulkarni, ... International Immunopharmacology 83, 106381, 2020 | 12 | 2020 |
| Heteromeric neuronal nicotinic acetylcholine receptors with mutant β subunits acquire sensitivity to α7-selective positive allosteric modulators C Stokes, S Garai, AR Kulkarni, LN Cantwell, CM Noviello, RE Hibbs, ... Journal of Pharmacology and Experimental Therapeutics 370 (2), 252-268, 2019 | 11 | 2019 |
| The positive allosteric modulation of alpha7-nicotinic cholinergic receptors by GAT107 increases bacterial lung clearance in hyperoxic mice by decreasing oxidative stress in … AG Gauthier, J Wu, M Lin, R Sitapara, A Kulkarni, GA Thakur, EE Schmidt, ... Antioxidants 10 (1), 135, 2021 | 9 | 2021 |
| Allosteric modulators of the cannabinoid 1 receptor GA Thakur, RB Tichkule, PM Kulkarni, AR Kulkarni US Patent 9,926,275, 2018 | 9 | 2018 |
| Negative allosteric modulation of CB1 cannabinoid receptor signaling suppresses opioid-mediated reward V Iyer, C Rangel-Barajas, TJ Woodward, A Kulkarni, L Cantwell, ... Pharmacological research 185, 106474, 2022 | 8 | 2022 |
