COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning E Ong, MU Wong, A Huffman, Y He Frontiers in Immunology 11, 1581, 2020 | 457 | 2020 |
Ontobee: A linked ontology data server to support ontology term dereferencing, linkage, query and integration E Ong, Z Xiang, B Zhao, Y Liu, Y Lin, J Zheng, C Mungall, M Courtot, ... Nucleic acids research 45 (D1), D347-D352, 2017 | 153 | 2017 |
Victors: a web-based knowledge base of virulence factors in human and animal pathogens S Sayers, L Li, E Ong, S Deng, G Fu, Y Lin, B Yang, S Zhang, Z Fa, ... Nucleic acids research 47 (D1), D693-D700, 2019 | 150 | 2019 |
CIDO, a community-based ontology for coronavirus disease knowledge and data integration, sharing, and analysis Y He, H Yu, E Ong, Y Wang, Y Liu, A Huffman, H Huang, J Beverley, J Hur, ... Scientific data 7 (1), 181, 2020 | 135 | 2020 |
Vaxign-ML: supervised machine learning reverse vaccinology model for improved prediction of bacterial protective antigens E Ong, H Wang, MU Wong, M Seetharaman, N Valdez, Y He Bioinformatics 36 (10), 3185-3191, 2020 | 100 | 2020 |
The eXtensible ontology development (XOD) principles and tool implementation to support ontology interoperability Y He, Z Xiang, J Zheng, Y Lin, JA Overton, E Ong Journal of biomedical semantics 9, 1-10, 2018 | 80 | 2018 |
Antibiotic Resistance Determinant-Focused Acinetobacter baumannii Vaccine Designed Using Reverse Vaccinology Z Ni, Y Chen, E Ong, Y He International journal of molecular sciences 18 (2), 458, 2017 | 64 | 2017 |
Vaxign2: the second generation of the first Web-based vaccine design program using reverse vaccinology and machine learning E Ong, MF Cooke, A Huffman, Z Xiang, MU Wong, H Wang, ... Nucleic acids research 49 (W1), W671-W678, 2021 | 62 | 2021 |
Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project E Ong, LL Wang, J Schaub, JF O’Toole, B Steck, AZ Rosenberg, F Dowd, ... Nature Reviews Nephrology 16 (11), 686-696, 2020 | 49 | 2020 |
Epitope promiscuity and population coverage of Mycobacterium tuberculosis protein antigens in current subunit vaccines under development E Ong, Y He, Z Yang Infection, Genetics and Evolution 80, 104186, 2020 | 29 | 2020 |
Identification of New Features from Known Bacterial Protective Vaccine Antigens Enhances Rational Vaccine Design E Ong, MU Wong, Y He Frontiers in Immunology 8, 1382, 2017 | 28 | 2017 |
Computational Design of SARS-CoV-2 Spike Glycoproteins to Increase Immunogenicity by T Cell Epitope Engineering E Ong, X Huang, R Pearce, Y Zhang, Y He Computational and Structural Biotechnology Journal 19, 518-529, 2021 | 23 | 2021 |
Identification of Drug Combinations Containing Imatinib for Treatment of BCR-ABL+ Leukemias Y Kang, A Hodges, E Ong, W Roberts, C Piermarocchi, G Paternostro PloS one 9 (7), e102221, 2014 | 22 | 2014 |
Prediction of kinase inhibitor response using activity profiling, in vitro screening, and elastic net regression TP Tran, E Ong, AP Hodges, G Paternostro, C Piermarocchi BMC Systems Biology 8, 1-10, 2014 | 21 | 2014 |
ODAE: Ontology-based systematic representation and analysis of drug adverse events and its usage in study of adverse events given different patient age and disease conditions H Yu, S Nysak, N Garg, E Ong, X Ye, X Zhang, Y He BMC bioinformatics 20, 117-128, 2019 | 15 | 2019 |
Ontological representation, integration, and analysis of LINCS cell line cells and their cellular responses E Ong, J Xie, Z Ni, Q Liu, S Sarntivijai, Y Lin, D Cooper, R Terryn, ... BMC bioinformatics 18, 43-53, 2017 | 14 | 2017 |
Bacterial whole-genome determination and applications Y He, E Ong, A Huffman Molecular medical microbiology, 511-525, 2024 | 13 | 2024 |
VIO: ontology classification and study of vaccine responses given various experimental and analytical conditions E Ong, P Sun, K Berke, J Zheng, G Wu, Y He BMC bioinformatics 20, 1-10, 2019 | 13 | 2019 |
OPMI: the Ontology of Precision Medicine and Investigation and its Support for Clinical Data and Metadata Representation and Analysis. Y He, E Ong, J Schaub, F Dowd, JF O'Toole, A Siapos, CG Reich, ... ICBO, 1-10, 2019 | 12 | 2019 |
VaximmutorDB: a web-based vaccine immune factor database and its application for understanding vaccine-induced immune mechanisms K Berke, P Sun, E Ong, N Sanati, A Huffman, T Brunson, F Loney, ... Frontiers in immunology 12, 639491, 2021 | 11 | 2021 |