kumar sanjiv
kumar sanjiv
SciLifelab, Karolinska Institutet, Stockholm, Sweden
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MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
H Gad, T Koolmeister, AS Jemth, S Eshtad, SA Jacques, CE Ström, ...
Nature 508 (7495), 215-221, 2014
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
KVM Huber, E Salah, B Radic, M Gridling, JM Elkins, A Stukalov, ...
Nature 508 (7495), 222-227, 2014
Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer
M Asim, F Tarish, HI Zecchini, K Sanjiv, E Gelali, CE Massie, A Baridi, ...
Nature communications 8 (1), 374, 2017
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation
T Visnes, A Cázares-Körner, W Hao, O Wallner, G Masuyer, O Loseva, ...
Science 362 (6416), 834-839, 2018
Cancer-specific synthetic lethality between ATR and CHK1 kinase activities
K Sanjiv, A Hagenkort, JM Calderón-Montańo, T Koolmeister, PM Reaper, ...
Cell reports 14 (2), 298-309, 2016
Targeting DNA repair, DNA metabolism and replication stress as anti‐cancer strategies
JC Puigvert, K Sanjiv, T Helleday
The FEBS journal 283 (2), 232-245, 2016
Validation and development of MTH1 inhibitors for treatment of cancer
UW Berglund, K Sanjiv, H Gad, C Kalderen, T Koolmeister, T Pham, ...
Annals of oncology 27 (12), 2275-2283, 2016
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
N Herold, SG Rudd, L Ljungblad, K Sanjiv, IH Myrberg, CBJ Paulin, ...
Nature medicine 23 (2), 256-263, 2017
Development of chitosan oligosaccharide-modified gold nanorods for in vivo targeted delivery and noninvasive imaging by NIR irradiation
S Charan, K Sanjiv, N Singh, FC Chien, YF Chen, NN Nergui, SH Huang, ...
Bioconjugate chemistry 23 (11), 2173-2182, 2012
SAMHD1 protects cancer cells from various nucleoside-based antimetabolites
N Herold, SG Rudd, K Sanjiv, J Kutzner, J Bladh, CBJ Paulin, T Helleday, ...
Cell Cycle 16 (11), 1029-1038, 2017
Global survey of the immunomodulatory potential of common drugs
GI Vladimer, B Snijder, N Krall, JW Bigenzahn, KVM Huber, CH Lardeau, ...
Nature chemical biology 13 (6), 681-690, 2017
Synthesis of tunable and multifunctional Ni-doped near-infrared QDs for cancer cell targeting and cellular sorting
N Singh, S Charan, K Sanjiv, SH Huang, YC Hsiao, CW Kuo, FC Chien, ...
Bioconjugate chemistry 23 (3), 421-430, 2012
The spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing
M Tanikawa, K Sanjiv, T Helleday, P Herr, O Mortusewicz
Oncogenesis 5 (12), e280-e280, 2016
With me or against me: Tumor suppressor and drug resistance activities of SAMHD1
N Herold, SG Rudd, K Sanjiv, J Kutzner, IH Myrberg, CBJ Paulin, ...
Experimental hematology 52, 32-39, 2017
Epidemiological typing of Staphylococcus aureus by DNA restriction fragment length polymorphism of coa gene
K Sanjiv, AK Kataria, R Sharma, G Singh
Veterinarski arhiv 78 (1), 31-38, 2008
Ribonucleotide reductase inhibitors suppress SAMHD 1 ara‐CTP ase activity enhancing cytarabine efficacy
SG Rudd, N Tsesmetzis, K Sanjiv, CBJ Paulin, L Sandhow, J Kutzner, ...
EMBO molecular medicine 12 (3), e10419, 2020
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
T Visnes, C Benítez-Buelga, A Cázares-Körner, K Sanjiv, BMF Hanna, ...
Nucleic acids research 48 (21), 12234-12251, 2020
Glioblastoma and glioblastoma stem cells are dependent on functional MTH1
L Pudelko, P Rouhi, K Sanjiv, H Gad, C Kalderén, A Höglund, M Squatrito, ...
Oncotarget 8 (49), 84671, 2017
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
N Bonagas, NMS Gustafsson, M Henriksson, P Marttila, R Gustafsson, ...
Nature cancer 3 (2), 156-172, 2022
Multidrug-resistant cells overexpressing P-glycoprotein are susceptible to DNA crosslinking agents due to attenuated Src/nuclear EGFR cascade-activated DNA repair activity
PC Lee, HJ Lee, R Kakadiya, K Sanjiv, TL Su, TC Lee
Oncogene 32 (9), 1144-1154, 2013
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