Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia CC Smith, Q Wang, CS Chin, S Salerno, LE Damon, MJ Levis, AE Perl, ... Nature, 2012 | 841 | 2012 |
Crenolanib is a selective type I pan-FLT3 inhibitor CC Smith, EA Lasater, KC Lin, Q Wang, MQ McCreery, WK Stewart, ... Proceedings of the National Academy of Sciences 111 (14), 5319-5324, 2014 | 244 | 2014 |
Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX MVAS Navarro, N De, N Bae, Q Wang, H Sondermann Structure 17 (8), 1104-1116, 2009 | 240 | 2009 |
Structural basis for calcium sensing by GCaMP2 Q Wang, B Shui, MI Kotlikoff, H Sondermann Structure 16 (12), 1817-1827, 2008 | 238 | 2008 |
Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin Q Wang, MVAS Navarro, G Peng, E Molinelli, S Lin Goh, BL Judson, ... Proceedings of the National Academy of Sciences 106 (31), 12700-12705, 2009 | 223 | 2009 |
Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate Q Wang, EM Vogan, LM Nocka, CE Rosen, JA Zorn, SC Harrison, ... Elife 4, e06074, 2015 | 109 | 2015 |
Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220) JA Zorn, Q Wang, E Fujimura, T Barros, J Kuriyan PloS one 10 (4), e0121177, 2015 | 99 | 2015 |
Analysis of the role of the C-terminal tail in the regulation of the epidermal growth factor receptor E Kovacs, R Das, Q Wang, TS Collier, A Cantor, Y Huang, K Wong, ... Molecular and Cellular Biology 35 (17), 3083-3102, 2015 | 98 | 2015 |
Structural basis for backtracking by the SARS-CoV-2 replication–transcription complex B Malone, J Chen, Q Wang, E Llewellyn, YJ Choi, PDB Olinares, X Cao, ... Proceedings of the National Academy of Sciences 118 (19), e2102516118, 2021 | 95 | 2021 |
An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor NH Shah, Q Wang, Q Yan, D Karandur, TA Kadlecek, IR Fallahee, ... Elife 5, e20105, 2016 | 93 | 2016 |
Structure and plasticity of Endophilin and Sorting Nexin 9 Q Wang, HYK Kaan, RN Hooda, SL Goh, H Sondermann Structure 16 (10), 1574-1587, 2008 | 91 | 2008 |
Estimating protein–ligand binding free energy: Atomic solvation parameters for partition coefficient and solvation free energy calculation J Pei, Q Wang, J Zhou, L Lai PROTEINS: Structure, Function, and Bioinformatics 57 (4), 651-664, 2004 | 90 | 2004 |
PSI‐DOCK: Towards highly efficient and accurate flexible ligand docking J Pei, Q Wang, Z Liu, Q Li, K Yang, L Lai Proteins: Structure, Function, and Bioinformatics 62 (4), 934-946, 2006 | 87 | 2006 |
Monovalent and Multivalent Ligation of the B Cell Receptor Exhibit Differential Dependence upon Syk and Src Family Kinases S Mukherjee, J Zhu, J Zikherman, R Parameswaran, TA Kadlecek, ... Science Signaling 6 (256), ra1, 2013 | 85 | 2013 |
A structural atlas of kinases inhibited by clinically approved drugs. Q Wang, JA Zorn, J Kuriyan Methods in enzymology 548, 23-67, 2014 | 59 | 2014 |
A structural atlas of kinases inhibited by clinically approved drugs Q Wang, JA Zorn, J Kuriyan Methods in enzymology 548, 23-67, 2014 | 59 | 2014 |
A structural model of a Ras–Raf signalosome VP Mysore, ZW Zhou, C Ambrogio, L Li, JN Kapp, C Lu, Q Wang, ... Nature Structural & Molecular Biology 28 (10), 847-857, 2021 | 58 | 2021 |
Structural mechanism for Bruton¢s tyrosine kinase activation at the cell membrane Q Wang, Y Pechersky, S Sagawa, AC Pan, DE Shaw Proceedings of the National Academy of Sciences 116 (19), 9390-9399, 2019 | 57 | 2019 |
Structure of the S1S2 glutamate binding domain of GluR3 AH Ahmed, Q Wang, H Sondermann, RE Oswald Proteins: Structure, Function, and Bioinformatics 75 (3), 628-637, 2009 | 56 | 2009 |
Evolutionary insights into premetazoan functions of the neuronal protein Homer P Burkhardt, M Grønborg, K McDonald, T Sulur, Q Wang, N King Molecular biology and evolution 31 (9), 2342-2355, 2014 | 53 | 2014 |