Adenovirus-associated virus vector–mediated gene transfer in hemophilia B AC Nathwani, EGD Tuddenham, S Rangarajan, C Rosales, J McIntosh, ... New England Journal of Medicine 365 (25), 2357-2365, 2011 | 2211 | 2011 |
Virus attenuation by genome-scale changes in codon pair bias JR Coleman, D Papamichail, S Skiena, B Futcher, E Wimmer, S Mueller Science 320 (5884), 1784-1787, 2008 | 802 | 2008 |
Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity S Mueller, D Papamichail, JR Coleman, S Skiena, E Wimmer Journal of virology 80 (19), 9687-9696, 2006 | 416 | 2006 |
Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins AC Nathwani, C Rosales, J McIntosh, G Rastegarlari, D Nathwani, D Raj, ... Molecular therapy 19 (5), 876-885, 2011 | 386 | 2011 |
Live attenuated influenza virus vaccines by computer-aided rational design S Mueller, JR Coleman, D Papamichail, CB Ward, A Nimnual, B Futcher, ... Nature biotechnology 28 (7), 723-726, 2010 | 331 | 2010 |
The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages JR Coleman Virology journal 4, 1-5, 2007 | 150 | 2007 |
Scalable live-attenuated SARS-CoV-2 vaccine candidate demonstrates preclinical safety and efficacy Y Wang, C Yang, Y Song, JR Coleman, M Stawowczyk, J Tafrova, ... Proceedings of the National Academy of Sciences 118 (29), e2102775118, 2021 | 126 | 2021 |
Genetically modified cyanobacteria for the production of ethanol, the constructs and method thereof RP Woods, JR Coleman, M De Deng US Patent 6,699,696, 2004 | 91 | 2004 |
Putting synthesis into biology: a viral view of genetic engineering through de novo gene and genome synthesis S Mueller, JR Coleman, E Wimmer Chemistry & biology 16 (3), 337-347, 2009 | 63 | 2009 |
A codon-pair deoptimized live-attenuated vaccine against respiratory syncytial virus is immunogenic and efficacious in non-human primates S Mueller, CB Stauft, R Kalkeri, F Koidei, A Kushnir, S Tasker, ... Vaccine 38 (14), 2943-2948, 2020 | 58 | 2020 |
Designed Reduction of Streptococcus pneumoniae Pathogenicity via Synthetic Changes in Virulence Factor Codon-pair Bias JR Coleman, D Papamichail, M Yano, MM García-Suárez, L Pirofski Journal of Infectious Diseases 203 (9), 1264-1273, 2011 | 53 | 2011 |
Genetically modified cyanobacteria for the production of ethanol, the constructs and method thereof RP Woods, JR Coleman, M De Deng US Patent 6,306,639, 2001 | 50 | 2001 |
Medication administration: the implementation process of bar-coding for medication administration to enhance medication safety. SO Foote, JR Coleman Nursing Economics 26 (3), 207-211, 2008 | 43 | 2008 |
Antibodies to Streptococcus pneumoniae capsular polysaccharide enhance pneumococcal quorum sensing M Yano, S Gohil, JR Coleman, C Manix, L Pirofski mbio 2 (5), 10.1128/mbio. 00176-11, 2011 | 42 | 2011 |
Early clinical trial results following administration of a low dose of a novel self complementary adeno-associated viral vector encoding human Factor IX in two subjects with … A Nathwani, E Tuddenham, C Rosales, J McIntosh, A Riddell, P Rustagi, ... Blood 116 (21), 248, 2010 | 30 | 2010 |
Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets CB Stauft, C Yang, JR Coleman, D Boltz, C Chin, A Kushnir, S Mueller PloS one 14 (10), e0223784, 2019 | 26 | 2019 |
Genetically modified cyanobacteria for the production of ethanol RP Woods, CR Smith, D Kramer, H Enke, U Duhring, K Baier, M Grundel, ... US Patent 9,650,642, 2017 | 22 | 2017 |
Codon context optimization in synthetic gene design D Papamichail, H Liu, V Machado, N Gould, JR Coleman, G Papamichail IEEE/ACM Transactions on Computational Biology and Bioinformatics 15 (2 …, 2016 | 19 | 2016 |
Vaccination of pigs with a codon-pair bias de-optimized live attenuated influenza vaccine protects from homologous challenge BS Kaplan, CK Souza, PC Gauger, CB Stauft, JR Coleman, S Mueller, ... Vaccine 36 (8), 1101-1107, 2018 | 17 | 2018 |
Attenuated viruses useful for vaccines E Wimmer, S Skiena, S Mueller, B Futcher, D Papamichail, JR Coleman, ... US Patent 9,476,032, 2016 | 17 | 2016 |