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Ludovic Sauguet
Ludovic Sauguet
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Year
Structure and pharmacology of pentameric receptor channels: from bacteria to brain
PJ Corringer, F Poitevin, MS Prevost, L Sauguet, M Delarue, ...
Structure 20 (6), 941-956, 2012
2642012
Cyclodipeptide synthases are a family of tRNA-dependent peptide bond–forming enzymes
M Gondry, L Sauguet, P Belin, R Thai, R Amouroux, C Tellier, K Tuphile, ...
Nature chemical biology 5 (6), 414-420, 2009
2462009
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation
L Sauguet, A Shahsavar, F Poitevin, C Huon, A Menny, À Nemecz, ...
Proceedings of the National Academy of Sciences 111 (3), 966-971, 2014
2162014
Structural basis for ion permeation mechanism in pentameric ligand‐gated ion channels
L Sauguet, F Poitevin, S Murail, C Van Renterghem, G Moraga‐Cid, ...
The EMBO journal 32 (5), 728-741, 2013
1572013
A locally closed conformation of a bacterial pentameric proton-gated ion channel
MS Prevost, L Sauguet, H Nury, C Van Renterghem, C Huon, F Poitevin, ...
Nature structural & molecular biology 19 (6), 642-649, 2012
1532012
Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel
L Sauguet, RJ Howard, L Malherbe, US Lee, PJ Corringer, R Adron Harris, ...
Nature communications 4 (1), 1697, 2013
1522013
Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis
L Sauguet, M Moutiez, Y Li, P Belin, J Seguin, MH Le Du, R Thai, ...
Nucleic acids research 39 (10), 4475-4489, 2011
982011
Flexible tethering of primase and DNA Pol á in the eukaryotic primosome
R Núñez-Ramírez, S Klinge, L Sauguet, R Melero, MA Recuero-Checa, ...
Nucleic acids research 39 (18), 8187-8199, 2011
772011
Shared active site architecture between the large subunit of eukaryotic primase and DNA photolyase
L Sauguet, S Klinge, RL Perera, JD Maman, L Pellegrini
PLoS One 5 (4), e10083, 2010
732010
Allosteric and hyperekplexic mutant phenotypes investigated on an á1 glycine receptor transmembrane structure
G Moraga-Cid, L Sauguet, C Huon, L Malherbe, C Girard-Blanc, S Petres, ...
Proceedings of the National Academy of Sciences 112 (9), 2865-2870, 2015
572015
Crystallographic studies of pharmacological sites in pentameric ligand-gated ion channels
L Sauguet, A Shahsavar, M Delarue
Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (3), 511-523, 2015
572015
Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography
L Sauguet, P Raia, G Henneke, M Delarue
Nature communications 7 (1), 12227, 2016
462016
An updated structural classification of replicative DNA polymerases
P Raia, M Delarue, L Sauguet
Biochemical Society Transactions 47 (1), 239-249, 2019
402019
Sites of anesthetic inhibitory action on a cationic ligand-gated ion channel
B Laurent, S Murail, A Shahsavar, L Sauguet, M Delarue, M Baaden
Structure 24 (4), 595-605, 2016
362016
Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA
C Madru, G Henneke, P Raia, I Hugonneau-Beaufet, G Pehau-Arnaudet, ...
Nature Communications 11 (1), 1591, 2020
352020
Structural basis for xenon inhibition in a cationic pentameric ligand-gated ion channel
L Sauguet, Z Fourati, T Prange, M Delarue, N Colloc'h
PLoS One 11 (2), e0149795, 2016
352016
Structural basis for a bimodal allosteric mechanism of general anesthetic modulation in pentameric ligand-gated ion channels
Z Fourati, RJ Howard, SA Heusser, H Hu, RR Ruza, L Sauguet, E Lindahl, ...
Cell reports 23 (4), 993-1004, 2018
332018
Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases
P Raia, M Carroni, E Henry, G Pehau-Arnaudet, S Brûlé, P Béguin, ...
PLoS biology 17 (1), e3000122, 2019
302019
Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel
H Hu, K Ataka, A Menny, Z Fourati, L Sauguet, PJ Corringer, P Koehl, ...
Proceedings of the National Academy of Sciences 115 (52), E12172-E12181, 2018
302018
Genuine open form of the pentameric ligand-gated ion channel GLIC
Z Fourati, L Sauguet, M Delarue
Acta Crystallographica Section D: Biological Crystallography 71 (3), 454-460, 2015
282015
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