Irene Ghobrial
Irene Ghobrial
Dana-Farber Cancer Institute
Verified email at - Homepage
Cited by
Cited by
Biological properties of extracellular vesicles and their physiological functions
M Yáñez-Mó, PRM Siljander, Z Andreu, A Bedina Zavec, FE Borràs, ...
Journal of extracellular vesicles 4 (1), 27066, 2015
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
JE Delmore, GC Issa, ME Lemieux, PB Rahl, J Shi, HM Jacobs, E Kastritis, ...
Cell 146 (6), 904-917, 2011
Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study
LH Nguyen, DA Drew, MS Graham, AD Joshi, CG Guo, W Ma, RS Mehta, ...
The Lancet Public Health 5 (9), e475-e483, 2020
Targeting apoptosis pathways in cancer therapy
IM Ghobrial, TE Witzig, AA Adjei
CA: a cancer journal for clinicians 55 (3), 178-194, 2005
Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
PG Richardson, E Weller, S Lonial, AJ Jakubowiak, S Jagannath, ...
Blood, The Journal of the American Society of Hematology 116 (5), 679-686, 2010
Ibrutinib in previously treated WaldenströmĘs macroglobulinemia
SP Treon, CK Tripsas, K Meid, D Warren, G Varma, R Green, ...
New England Journal of Medicine 372 (15), 1430-1440, 2015
BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression
AM Roccaro, A Sacco, P Maiso, AK Azab, YT Tai, M Reagan, F Azab, ...
The Journal of clinical investigation 123 (4), 1542-1555, 2013
The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee
E Campo, ES Jaffe, JR Cook, L Quintanilla-Martinez, SH Swerdlow, ...
Blood, The Journal of the American Society of Hematology 140 (11), 1229-1253, 2022
Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma
TE Witzig, SM Geyer, I Ghobrial, DJ Inwards, R Fonseca, P Kurtin, ...
J Clin Oncol 23 (23), 5347-5356, 2005
Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)–dependent migration and homing in multiple myeloma
Y Alsayed, H Ngo, J Runnels, X Leleu, UK Singha, CM Pitsillides, ...
Blood 109 (7), 2708-2717, 2007
Genomic complexity of multiple myeloma and its clinical implications
S Manier, KZ Salem, J Park, DA Landau, G Getz, IM Ghobrial
Nature reviews Clinical oncology 14 (2), 100-113, 2017
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
AK Azab, JM Runnels, C Pitsillides, AS Moreau, F Azab, X Leleu, X Jia, ...
Blood, The Journal of the American Society of Hematology 113 (18), 4341-4351, 2009
International Myeloma Working Group recommendations for the diagnosis and management of myeloma-related renal impairment
MA Dimopoulos, P Sonneveld, N Leung, G Merlini, H Ludwig, E Kastritis, ...
Journal of Clinical Oncology 34 (13), 1544-1557, 2016
Elevated IL-17 produced by Th17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma
RH Prabhala, D Pelluru, M Fulciniti, HK Prabhala, P Nanjappa, W Song, ...
Blood, The Journal of the American Society of Hematology 115 (26), 5385-5392, 2010
MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma
AM Roccaro, A Sacco, B Thompson, X Leleu, AK Azab, F Azab, J Runnels, ...
Blood, The Journal of the American Society of Hematology 113 (26), 6669-6680, 2009
Bone marrow microenvironment in multiple myeloma progression
S Manier, A Sacco, X Leleu, IM Ghobrial, AM Roccaro
BioMed Research International 2012, 2012
Targeting the bone marrow microenvironment in multiple myeloma
Y Kawano, M Moschetta, S Manier, S Glavey, GT Görgün, AM Roccaro, ...
Immunological reviews 263 (1), 160-172, 2015
A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma
TE Witzig, CB Reeder, BR LaPlant, M Gupta, PB Johnston, IN Micallef, ...
Leukemia 25 (2), 341-347, 2011
Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features
AK Azab, J Hu, P Quang, F Azab, C Pitsillides, R Awwad, B Thompson, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5782-5794, 2012
Bone marrow niches in haematological malignancies
S Méndez-Ferrer, D Bonnet, DP Steensma, RP Hasserjian, IM Ghobrial, ...
Nature Reviews Cancer 20 (5), 285-298, 2020
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