| Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity E Volz, V Hill, JT McCrone, A Price, D Jorgensen, Á O’Toole, J Southgate, ... Cell 184 (1), 64-75. e11, 2021 | 1120 | 2021 |
| Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B. 1.617. 2) compared with alpha (B. 1.1. 7) variants of concern: a cohort study KA Twohig, T Nyberg, A Zaidi, S Thelwall, MA Sinnathamby, S Aliabadi, ... The Lancet Infectious Diseases 22 (1), 35-42, 2022 | 856 | 2022 |
| Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7 B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira, S Marelli, WT Harvey, ... Cell reports 35 (13), 2021 | 445 | 2021 |
| Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B. 1.1. 7: an ecological study MS Graham, CH Sudre, A May, M Antonelli, B Murray, T Varsavsky, ... The Lancet Public Health 6 (5), e335-e345, 2021 | 366 | 2021 |
| Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor … J Shima, A Hesketh, S Okamoto, S Kawamoto, K Ochi Journal of bacteriology 178 (24), 7276-7284, 1996 | 346 | 1996 |
| The global role of ppGpp synthesis in morphological differentiation and antibiotic production in Streptomyces coelicolor A3(2) A Hesketh, WJ Chen, J Ryding, S Chang, M Bibb Genome biology 8, 1-18, 2007 | 196 | 2007 |
| Primary and secondary metabolism, and post‐translational protein modifications, as portrayed by proteomic analysis of Streptomyces coelicolor AR Hesketh, G Chandra, AD Shaw, JJ Rowland, DB Kell, MJ Bibb, ... Molecular microbiology 46 (4), 917-932, 2002 | 161 | 2002 |
| Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant P Elliott, D Haw, H Wang, O Eales, CE Walters, KEC Ainslie, C Atchison, ... Science 374 (6574), eabl9551, 2021 | 128 | 2021 |
| Induction of ppGpp synthesis in Streptomyces coelicolor A3(2) grown under conditions of nutritional sufficiency elicits actII‐ORF4 transcription and actinorhodin … A Hesketh, J Sun, M Bibb Molecular microbiology 39 (1), 136-144, 2001 | 119 | 2001 |
| Functional Analysis of relA andrshA, Two relA/spoT Homologues ofStreptomyces coelicolor A3(2) J Sun, A Hesketh, M Bibb Journal of bacteriology 183 (11), 3488-3498, 2001 | 117 | 2001 |
| The GlnD and GlnK homologues of Streptomyces coelicolor A3(2) are functionally dissimilar to their nitrogen regulatory system counterparts from enteric bacteria A Hesketh, D Fink, B Gust, HU Rexer, B Scheel, K Chater, W Wohlleben, ... Molecular microbiology 46 (2), 319-330, 2002 | 105 | 2002 |
| PEDRo: a database for storing, searching and disseminating experimental proteomics data K Garwood, T McLaughlin, C Garwood, S Joens, N Morrison, CF Taylor, ... Bmc Genomics 5, 1-11, 2004 | 97 | 2004 |
| A novel method for improving Streptomyces coelicolor A3 (2) for production of actinorhodin by introduction of rpsL (encoding ribosomal protein S12) mutations conferring … A HESKETH, K OCHI The Journal of Antibiotics 50 (6), 532-535, 1997 | 90 | 1997 |
| The role of absC, a novel regulatory gene for secondary metabolism, in zinc‐dependent antibiotic production in Streptomyces coelicolor A3(2) A Hesketh, H Kock, S Mootien, M Bibb Molecular microbiology 74 (6), 1427-1444, 2009 | 86 | 2009 |
| Changes in the Extracellular Proteome Caused by the Absence of the bldA Gene Product, a Developmentally Significant tRNA, Reveal a New Target for the Pleiotropic … DW Kim, K Chater, KJ Lee, A Hesketh Journal of bacteriology 187 (9), 2957-2966, 2005 | 81 | 2005 |
| Molecular and functional analysis of the ribosomal L11 and S12 protein genes (rplK and rpsL) of Streptomyces coelicolor A3(2) K Ochi, D Zhang, S Kawamoto, A Hesketh Molecular and General Genetics MGG 256, 488-498, 1997 | 80 | 1997 |
| Expression analysis of the ssgA gene product, associated with sporulation and cell division in Streptomyces griseus S Kawamoto, H Watanabe, A Hesketh, JC Ensign, K Ochi Microbiology 143 (4), 1077-1086, 1997 | 80 | 1997 |
| Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: negative regulation of secondary metabolism by (p) ppGpp JP Gomez-Escribano, JF Martín, A Hesketh, MJ Bibb, P Liras Microbiology 154 (3), 744-755, 2008 | 78 | 2008 |
| Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope A Hesketh, C Hill, J Mokhtar, G Novotna, N Tran, M Bibb, HJ Hong BMC genomics 12, 1-20, 2011 | 76 | 2011 |
| New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor, revealed by combined proteomic and transcriptomic analysis of liquid cultures A Hesketh, G Bucca, E Laing, F Flett, G Hotchkiss, CP Smith, KF Chater BMC genomics 8, 1-22, 2007 | 71 | 2007 |
