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John W. Tomsho, Ph.D.
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Year
Ring Structure and Aromatic Substituent Effects on the pKa of the Benzoxaborole Pharmacophore
JW Tomsho, A Pal, DG Hall, SJ Benkovic
ACS medicinal chemistry letters 3 (1), 48-52, 2012
1422012
The unique chemistry of benzoxaboroles: current and emerging applications in biotechnology and therapeutic treatments
CT Liu, JW Tomsho, SJ Benkovic
Bioorganic & medicinal chemistry 22 (16), 4462-4473, 2014
1212014
Microtubule-assisted mechanism for functional metabolic macromolecular complex formation
S An, Y Deng, JW Tomsho, M Kyoung, SJ Benkovic
Proceedings of the National Academy of Sciences 107 (29), 12872-12876, 2010
1122010
Elucidation of the mechanism of the reaction between phenylboronic acid and a model diol, Alizarin Red S
JW Tomsho, SJ Benkovic
The Journal of Organic Chemistry 77 (5), 2098-2106, 2012
1092012
Discovery of antibacterial cyclic peptides that inhibit the ClpXP protease
L Cheng, TA Naumann, AR Horswill, SJ Hong, BJ Venters, JW Tomsho, ...
Protein Science 16 (8), 1535-1542, 2007
902007
Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid
WR Davis, J Tomsho, S Nikam, EM Cook, D Somand, JA Peliska
Biochemistry 39 (46), 14279-14291, 2000
672000
Examination of the Reactivity of Benzoxaboroles and Related Compounds with a cis-Diol
JW Tomsho, SJ Benkovic
The Journal of Organic Chemistry 77 (24), 11200-11209, 2012
362012
Vacuum matrix-assisted ionization source offering simplicity, sensitivity, and exceptional robustness in mass spectrometry
S Trimpin, M Pophristic, A Adeniji-Adele, JW Tomsho, CN McEwen
Analytical chemistry 90 (19), 11188-11192, 2018
262018
Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay
SA El-Mowafi, E Sineva, JN Alumasa, H Nicoloff, JW Tomsho, SE Ades, ...
Antimicrobial agents and chemotherapy 59 (1), 193-205, 2015
252015
Concentration-dependent processivity of multiple glutamate ligations catalyzed by folylpoly-γ-glutamate synthetase
JW Tomsho, RG Moran, JK Coward
Biochemistry 47 (34), 9040-9050, 2008
202008
Synthesis of (6 R)-and (6 S)-5, 10-dideazatetrahydrofolate oligo-γ-glutamates: Kinetics of multiple glutamate ligations catalyzed by folylpoly-γ-glutamate synthetase
JW Tomsho, JJ McGuire, JK Coward
Organic & biomolecular chemistry 3 (18), 3388-3398, 2005
152005
Protection of the benzoxaborole moiety: Synthesis and functionalization of zwitterionic benzoxaborole complexes
JM Gamrat, G Mancini, SJ Burke, RC Colandrea, NR Sadowski, BC Figula, ...
The Journal of Organic Chemistry 83 (11), 6193-6201, 2018
122018
Potassium haloalkyltrifluoroborate salts: synthesis, application, and reversible ligand replacement with MIDA
SJ Burke, JM Gamrat, JR Santhouse, DT Tomares, JW Tomsho
Tetrahedron letters 56 (41), 5500-5503, 2015
122015
Synthesis and Antimicrobial Evaluation of γ-Borono Phosphonate Compounds in Escherichia coli and Mycobacterium smegmatis
G Mancini, M Bouda, JM Gamrat, JW Tomsho
ACS omega 4 (11), 14551-14559, 2019
92019
Boronic and borinic acid compound as inhibitors of sulfenic acid-containing proteins
S Benkovic, C Liu, JW Tomsho
US Patent 9,309,508, 2016
82016
Inhibition of human folylpolyglutamate synthetase by diastereomeric phosphinic acid mimics of the tetrahedral intermediate
JJ McGuire, DM Bartley, JW Tomsho, WH Haile, JK Coward
Archives of biochemistry and biophysics 488 (2), 140-145, 2009
72009
Folylpoly-γ-glutamate synthetase: Kinetics of multiple glutamate ligations
JW Tomsho
University of Michigan, 2005
32005
Boronic and borinic acid compounds as inhibitors of sulfenic acid-containing proteins
S Benkovic, C Liu, JW Tomsho
US Patent 8,980,544, 2015
22015
Synthesis of Boron-Containing Nucleoside Analogs
LM Alhthlol, CL Orme, BS Jefferis, SA Herter, HE Kemper, JW Tomsho
The Journal of Organic Chemistry 89 (3), 1556-1566, 2024
12024
Protective groups and methods for protecting benzoxaboroles or oxaboroles
JW Tomsho, JM Gamrat
US Patent 11,427,603, 2022
12022
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