Mutations in cytoplasmic loops of the KCNQ1 channel and the risk of life-threatening events: implications for mutation-specific response to β-blocker therapy in type 1 long-QT … A Barsheshet, I Goldenberg, J O-Uchi, AJ Moss, C Jons, W Shimizu, ... Circulation 125 (16), 1988-1996, 2012 | 215 | 2012 |
Prognostic significance of epidermal growth factor receptor phosphorylation and mutation in head and neck squamous cell carcinoma T Hama, Y Yuza, Y Saito, J O-uchi, S Kondo, M Okabe, H Yamada, T Kato, ... The oncologist 14 (9), 900-908, 2009 | 143 | 2009 |
Mitochondrial ion channels/transporters as sensors and regulators of cellular redox signaling J O-Uchi, SY Ryu, BS Jhun, S Hurst, SS Sheu Antioxidants & redox signaling 21 (6), 987-1006, 2014 | 85 | 2014 |
Interaction of α1-Adrenoceptor Subtypes With Different G Proteins Induces Opposite Effects on Cardiac L-type Ca2+ Channel J O-Uchi, H Sasaki, S Morimoto, Y Kusakari, H Shinji, T Obata, K Hongo, ... Circulation research 102 (11), 1378-1388, 2008 | 84 | 2008 |
Posttranslational modifications of mitochondrial fission and fusion proteins in cardiac physiology and pathophysiology SM Adaniya, J O-Uchi, MW Cypress, Y Kusakari, BS Jhun American Journal of Physiology-Cell Physiology 316 (5), C583-C604, 2019 | 79 | 2019 |
Adrenergic Signaling Regulates Mitochondrial Ca2+ Uptake Through Pyk2-Dependent Tyrosine Phosphorylation of the Mitochondrial Ca2+ Uniporter J O-Uchi, BS Jhun, S Xu, S Hurst, A Raffaello, X Liu, B Yi, H Zhang, ... Antioxidants & redox signaling 21 (6), 863-879, 2014 | 78 | 2014 |
Molecular basis of decreased Kir4. 1 function in SeSAME/EAST syndrome DM Williams, CMB Lopes, A Rosenhouse-Dantsker, HL Connelly, ... Journal of the American Society of Nephrology 21 (12), 2117-2129, 2010 | 77 | 2010 |
α1-Adrenoceptor stimulation potentiates L-type Ca2+ current through Ca2+/calmodulin-dependent PK II (CaMKII) activation in rat ventricular myocytes J O-Uchi, K Komukai, Y Kusakari, T Obata, K Hongo, H Sasaki, S Kurihara Proceedings of the National Academy of Sciences 102 (26), 9400-9405, 2005 | 69 | 2005 |
Trigger-specific ion-channel mechanisms, risk factors, and response to therapy in type 1 long QT syndrome I Goldenberg, P Thottathil, CM Lopes, AJ Moss, S McNitt, O Jin, ... Heart Rhythm 9 (1), 49-56, 2012 | 60 | 2012 |
Molecular and functional identification of a mitochondrial ryanodine receptor in neurons R Jakob, G Beutner, VK Sharma, Y Duan, RA Gross, S Hurst, BS Jhun, ... Neuroscience letters 575, 7-12, 2014 | 56 | 2014 |
Use of mutant-specific ion channel characteristics for risk stratification of long QT syndrome patients C Jons, J O-Uchi, AJ Moss, M Reumann, JJ Rice, I Goldenberg, W Zareba, ... Science translational medicine 3 (76), 76ra28-76ra28, 2011 | 53 | 2011 |
The Mitochondrial Ca2+ Uniporter: Structure, Function, and Pharmacology J Mishra, BS Jhun, S Hurst, J O-Uchi, G Csordás, SS Sheu Pharmacology of Mitochondria, 129-156, 2017 | 49 | 2017 |
Pharmacological Modulation of Mitochondrial Ca2+ Content Regulates Sarcoplasmic Reticulum Ca2+ Release via Oxidation of the Ryanodine Receptor by … S Hamilton, R Terentyeva, TY Kim, P Bronk, RT Clements, J O-Uchi, ... Frontiers in physiology 9, 1831, 2018 | 48 | 2018 |
Protein kinase D activation induces mitochondrial fragmentation and dysfunction in cardiomyocytes BS Jhun, J O‐Uchi, SM Adaniya, TJ Mancini, JL Cao, ME King, AK Landi, ... The Journal of physiology 596 (5), 827-855, 2018 | 46 | 2018 |
Acidosis or inorganic phosphate enhances the length dependence of tension in rat skinned cardiac muscle N Fukuda, J O‐Uchi, D Sasaki, H Kajiwara, S Ishiwata, S Kurihara The Journal of Physiology 536 (1), 153-160, 2001 | 45 | 2001 |
In silico cardiac risk assessment in patients with long QT syndrome: type 1: clinical predictability of cardiac models R Hoefen, M Reumann, I Goldenberg, AJ Moss, J O-Uchi, Y Gu, S McNitt, ... Journal of the American College of Cardiology 60 (21), 2182-2191, 2012 | 43 | 2012 |
Activation of anoctamin-1 limits pulmonary endothelial cell proliferation via p38–Mitogen-activated protein Kinase–dependent apoptosis AM Allawzi, A Vang, RT Clements, BS Jhun, NR Kue, TJ Mancini, ... American journal of respiratory cell and molecular biology 58 (5), 658-667, 2018 | 42 | 2018 |
Adrenergic Signaling Controls RGK-Dependent Trafficking of Cardiac Voltage-Gated L-Type Ca2+ Channels Through PKD1 BS Jhun, J O-Uchi, W Wang, CH Ha, J Zhao, JY Kim, C Wong, RT Dirksen, ... Circulation research 110 (1), 59-70, 2012 | 38 | 2012 |
Overexpression of ryanodine receptor type 1 enhances mitochondrial fragmentation and Ca2+-induced ATP production in cardiac H9c2 myoblasts J O-Uchi, BS Jhun, S Hurst, S Bisetto, P Gross, M Chen, S Kettlewell, ... American Journal of Physiology-Heart and Circulatory Physiology 305 (12 …, 2013 | 37 | 2013 |
Role of Ca2+/calmodulin-dependent protein kinase II in the regulation of the cardiac L-type Ca2+ current during endothelin-1 stimulation K Komukai, J O-Uchi, S Morimoto, M Kawai, K Hongo, M Yoshimura, ... American Journal of Physiology-Heart and Circulatory Physiology 298 (6 …, 2010 | 36 | 2010 |