| Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis TS Adams, JC Schupp, S Poli, EA Ayaub, N Neumark, F Ahangari, ... Science advances 6 (28), eaba1983, 2020 | 816 | 2020 |
| The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis PS Kolb, EA Ayaub, W Zhou, V Yum, JG Dickhout, K Ask The international journal of biochemistry & cell biology 61, 45-52, 2015 | 251 | 2015 |
| GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin‐induced pulmonary fibrosis EA Ayaub, PS Kolb, Z Mohammed‐Ali, V Tat, J Murphy, PS Bellaye, ... The Journal of pathology 239 (4), 411-425, 2016 | 115 | 2016 |
| The importance of interventional timing in the bleomycin model of pulmonary fibrosis P Kolb, C Upagupta, M Vierhout, E Ayaub, PS Bellaye, J Gauldie, ... European Respiratory Journal 55 (6), 2020 | 107 | 2020 |
| Characterization of the COPD alveolar niche using single-cell RNA sequencing M Sauler, JE McDonough, TS Adams, N Kothapalli, T Barnthaler, ... Nature communications 13 (1), 494, 2022 | 92 | 2022 |
| Protein misfolding and endoplasmic reticulum stress in chronic lung disease J Wei, S Rahman, EA Ayaub, JG Dickhout, K Ask Chest 143 (4), 1098-1105, 2013 | 91 | 2013 |
| Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis EA Ayaub, A Dubey, J Imani, F Botelho, MRJ Kolb, CD Richards, K Ask Scientific Reports 7 (1), 13281, 2017 | 89 | 2017 |
| Palmitic acid–rich high-fat diet exacerbates experimental pulmonary fibrosis by modulating endoplasmic reticulum stress SG Chu, JA Villalba, X Liang, K Xiong, K Tsoyi, B Ith, EA Ayaub, ... American Journal of Respiratory Cell and Molecular Biology 61 (6), 737-746, 2019 | 82 | 2019 |
| Mechanical stress-induced mast cell degranulation activates TGF-â1 signalling pathway in pulmonary fibrosis C Shimbori, C Upagupta, PS Bellaye, EA Ayaub, S Sato, T Yanagihara, ... Thorax 74 (5), 455-465, 2019 | 81 | 2019 |
| Targeted inhibition of PI3 kinase/mTOR specifically in fibrotic lung fibroblasts suppresses pulmonary fibrosis in experimental models SU Hettiarachchi, YH Li, J Roy, F Zhang, E Puchulu-Campanella, ... Science translational medicine 12 (567), eaay3724, 2020 | 62 | 2020 |
| Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis F Zhang, EA Ayaub, B Wang, E Puchulu‐Campanella, YH Li, ... EMBO Molecular Medicine, e12034, 2020 | 61 | 2020 |
| Disruption of calcium signaling in fibroblasts and attenuation of bleomycin-induced fibrosis by nifedipine S Mukherjee, E A. Ayaub, J Murphy, C Lu, M Kolb, K Ask, L J. Janssen American journal of respiratory cell and molecular biology 53 (4), 450-458, 2015 | 50 | 2015 |
| Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy R Van Krieken, N Mehta, T Wang, M Zheng, R Li, B Gao, E Ayaub, K Ask, ... Journal of Biological Chemistry 294 (19), 7755-7768, 2019 | 41 | 2019 |
| Separate roles of IL‐6 and oncostatin M in mouse macrophage polarization in vitro and in vivo A Dubey, L Izakelian, EA Ayaub, L Ho, K Stephenson, S Wong, K Kwofie, ... Immunology and Cell Biology 96 (3), 257-272, 2018 | 29 | 2018 |
| Nintedanib attenuates the polarization of profibrotic macrophages through the inhibition of tyrosine phosphorylation on CSF1 receptor K Tandon, F Herrmann, E Ayaub, P Parthasarathy, M Ackermann, ... A72. MECHANISMS DRIVING FIBROSIS, A2397-A2397, 2017 | 29 | 2017 |
| Singlecell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis. Sci. Adv. 6, eaba1983 TS Adams, JC Schupp, S Poli, EA Ayaub, N Neumark, F Ahangari, ... | 23 | 2020 |
| IL‐6 mediates ER expansion during hyperpolarization of alternatively activated macrophages EA Ayaub, K Tandon, M Padwal, J Imani, H Patel, A Dubey, O Mekhael, ... Immunology and Cell Biology 97 (2), 203-217, 2019 | 23 | 2019 |
| Single cell RNA-seq and mass cytometry reveals a novel and a targetable population of macrophages in idiopathic pulmonary fibrosis EA Ayaub, S Poli, J Ng, T Adams, J Schupp, L Quesada-Arias, F Poli, ... BioRxiv, 2021.01. 04.425268, 2021 | 22 | 2021 |
| IL-33 mediates lung inflammation by the IL-6-type cytokine oncostatin M F Botelho, A Dubey, EA Ayaub, R Park, A Yip, A Humbles, R Kolbeck, ... Mediators of Inflammation 2020, 2020 | 14 | 2020 |
| FK506-binding protein 13 expression is upregulated in interstitial lung disease and correlated with clinical severity. A potentially protective role V Tat, EA Ayaub, A Ayoub, M Vierhout, S Naiel, MK Padwal, S Abed, ... American Journal of Respiratory Cell and Molecular Biology 64 (2), 235-246, 2021 | 11 | 2021 |
