The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans. SM De Morais, GR Wilkinson, J Blaisdell, K Nakamura, UA Meyer, ... Journal of Biological Chemistry 269 (22), 15419-15422, 1994 | 1329 | 1994 |
Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese. SM De Morais, GR Wilkinson, J Blaisdell, UA Meyer, K Nakamura, ... Molecular pharmacology 46 (4), 594-598, 1994 | 1024 | 1994 |
Characterization of the common genetic defect in humans deficient in debrisoquine metabolism FJ Gonzalez, RC Skodat, S Kimura, M Umeno, UM Zanger, DW Nebert, ... Nature 331 (6155), 442-446, 1988 | 909 | 1988 |
Pharmacogenetics and adverse drug reactions UA Meyer The Lancet 356 (9242), 1667-1671, 2000 | 869 | 2000 |
Molecular mechanisms of genetic polymorphisms of drug metabolism UA Meyer, UM Zanger Annual review of pharmacology and toxicology 37 (1), 269-296, 1997 | 762 | 1997 |
Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4. T Kronbach, D Mathys, M Umeno, FJ Gonzalez, UA Meyer Molecular pharmacology 36 (1), 89-96, 1989 | 706 | 1989 |
Cyclosporine metabolism in human liver: identification of a cytochrome P‐450III gene family as the major cyclosporine‐metabolizing enzyme explains interactions of cyclosporine … T Kronbach, V Fischer, UA Meyer Clinical Pharmacology & Therapeutics 43 (6), 630-635, 1988 | 703 | 1988 |
Nomenclature for human CYP2D6 alleles AK Daly, J Brockmoller, F Broly, M Eichelbaum, WE Evans, FJ Gonzalez, ... Pharmacogenetics and Genomics 6 (3), 193-201, 1996 | 604 | 1996 |
The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene. S Kimura, M Umeno, RC Skoda, UA Meyer, FJ Gonzalez American journal of human genetics 45 (6), 889, 1989 | 601 | 1989 |
Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification M Heim, UA Meyer The Lancet 336 (8714), 529-532, 1990 | 598 | 1990 |
Induction of drug metabolism: the role of nuclear receptors C Handschin, UA Meyer Pharmacological reviews 55 (4), 649-673, 2003 | 593 | 2003 |
Cytochrome P-450 hPCN3, a Novel Cytochrome P-450 IIIA Gene Product That Is Differentially Expressed in Adult Human Liver: cDNA and deduced amino acid sequence and distinct … T Aoyama, S Yamano, DJ Waxman, DP Lapenson, UA Meyer, V Fischer, ... Journal of Biological Chemistry 264 (18), 10388-10395, 1989 | 592 | 1989 |
Human Arylamine N-Acetyltransferase Genes: Isolation, Chromosomal Localization, and Functional Expression M Blum, DM Grant, W McBride, M Heim, UA Meyer DNA and cell biology 9 (3), 193-203, 1990 | 575 | 1990 |
Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution D Marez, M Legrand, N Sabbagh, JML Guidice, C Spire, JJ Lafitte, ... Pharmacogenetics and Genomics 7 (3), 193-202, 1997 | 554 | 1997 |
Parenchymal cells from adult rat liver in nonproliferating monolayer culture: I. Functional studies DM Bissell, LE Hammaker, UA Meyer The Journal of cell biology 59 (3), 722, 1973 | 551 | 1973 |
Pharmacogenetics–five decades of therapeutic lessons from genetic diversity UA Meyer Nature Reviews Genetics 5 (9), 669-676, 2004 | 522 | 2004 |
Nomenclature for N-acetyltransferases KP Vatsis, WW Weber, DA Bell, JM Dupret, DAP Evans, DM Grant, ... Pharmacogenetics and Genomics 5 (1), 1-17, 1995 | 510 | 1995 |
Molecular mechanism of slow acetylation of drugs and carcinogens in humans. M Blum, A Demierre, DM Grant, M Heim, UA Meyer Proceedings of the National Academy of Sciences 88 (12), 5237-5241, 1991 | 491 | 1991 |
Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1α C Handschin, J Lin, J Rhee, AK Peyer, S Chin, PH Wu, UA Meyer, ... Cell 122 (4), 505-515, 2005 | 457 | 2005 |
Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by … M Kagimoto, M Heim, K Kagimoto, T Zeugin, UA Meyer Journal of Biological Chemistry 265 (28), 17209-17214, 1990 | 416 | 1990 |