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Anthony P. Burgard
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Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization
AP Burgard, P Pharkya, CD Maranas
Biotechnology and bioengineering 84 (6), 647-657, 2003
15372003
Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol
H Yim, R Haselbeck, W Niu, C Pujol-Baxley, A Burgard, J Boldt, ...
Nature chemical biology 7 (7), 445-452, 2011
13212011
OptStrain: a computational framework for redesign of microbial production systems
P Pharkya, AP Burgard, CD Maranas
Genome research 14 (11), 2367-2376, 2004
6172004
Flux coupling analysis of genome-scale metabolic network reconstructions
AP Burgard, EV Nikolaev, CH Schilling, CD Maranas
Genome research 14 (2), 301-312, 2004
5172004
In silico design and adaptive evolution of Escherichia coli for production of lactic acid
SS Fong, AP Burgard, CD Herring, EM Knight, FR Blattner, CD Maranas, ...
Biotechnology and bioengineering 91 (5), 643-648, 2005
4912005
Optimization‐based framework for inferring and testing hypothesized metabolic objective functions
AP Burgard, CD Maranas
Biotechnology and bioengineering 82 (6), 670-677, 2003
3002003
Development of a commercial scale process for production of 1, 4-butanediol from sugar
A Burgard, MJ Burk, R Osterhout, S Van Dien, H Yim
Current opinion in biotechnology 42, 118-125, 2016
2952016
Minimal Reaction Sets for Escherichia coli Metabolism under Different Growth Requirements and Uptake Environments
AP Burgard, S Vaidyaraman, CD Maranas
Biotechnology progress 17 (5), 791-797, 2001
2152001
Methods and organisms for the growth-coupled production of 1, 4-butanediol
AP Burgard, SJ Van Dien, M Burk
US Patent 7,947,483, 2011
1972011
Exploring the overproduction of amino acids using the bilevel optimization framework OptKnock
P Pharkya, AP Burgard, CD Maranas
Biotechnology and bioengineering 84 (7), 887-899, 2003
1902003
Method and system for modeling cellular metabolism
CD Maranas, AP Burgard
US Patent 7,711,490, 2010
1872010
Method for determining gene knockouts
CD Maranas, AR Burgard, P Pharkya
US Patent 8,027,821, 2011
1822011
Probing the performance limits of the Escherichia coli metabolic network subject to gene additions or deletions
AP Burgard, CD Maranas
Biotechnology and bioengineering 74 (5), 364-375, 2001
1702001
Predicting biological system objectives de novo from internal state measurements
EP Gianchandani, MA Oberhardt, AP Burgard, CD Maranas, JA Papin
BMC bioinformatics 9, 1-13, 2008
1432008
Geobacter sulfurreducens strain engineered for increased rates of respiration
M Izallalen, R Mahadevan, A Burgard, B Postier, R Didonato Jr, J Sun, ...
Metabolic engineering 10 (5), 267-275, 2008
1422008
Compositions and methods for the biosynthesis of 1, 4-butanediol and its precursors
MJ Burk, SJ Van Dien, AP Burgard, W Niu
US Patent 8,067,214, 2011
1392011
Metabolic flux elucidation for large-scale models using 13C labeled isotopes
PF Suthers, AP Burgard, MS Dasika, F Nowroozi, S Van Dien, ...
Metabolic engineering 9 (5-6), 387-405, 2007
1292007
Microorganisms for the production of adipic acid and other compounds
AP Burgard, P Pharkya, RE Osterhout
US Patent 7,799,545, 2010
1272010
Microorganisms and methods for the biosynthesis of butadiene
MJ Burk, AP Burgard, J Sun, RE Osterhout, P Pharkya
US Patent 8,580,543, 2013
108*2013
Methods and organisms for the growth-coupled production of succinate
A Burgard, S Van Dien
US Patent App. 11/518,502, 2007
1062007
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