Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies DP Smith, TW Knapman, I Campuzano, RW Malham, JT Berryman, ... European journal of mass spectrometry 15 (2), 113-130, 2009 | 410 | 2009 |
Dopamine promotes α‐synuclein aggregation into SDS‐resistant soluble oligomers via a distinct folding pathway R Cappai, SL Leck, DJ Tew, NA Williamson, DP Smith, D Galatis, ... The FASEB journal 19 (10), 1377-1379, 2005 | 323 | 2005 |
Hierarchical assembly of β2-microglobulin amyloid in vitro revealed by atomic force microscopy NM Kad, SL Myers, DP Smith, DA Smith, SE Radford, NH Thomson Journal of molecular biology 330 (4), 785-797, 2003 | 262 | 2003 |
Platinum-based inhibitors of amyloid-β as therapeutic agents for Alzheimer's disease KJ Barnham, VB Kenche, GD Ciccotosto, DP Smith, DJ Tew, X Liu, ... Proceedings of the National Academy of Sciences 105 (19), 6813-6818, 2008 | 238 | 2008 |
Copper-mediated amyloid-β toxicity is associated with an intermolecular histidine bridge DP Smith, DG Smith, CC Curtain, JF Boas, JR Pilbrow, GD Ciccotosto, ... Journal of Biological Chemistry 281 (22), 15145-15154, 2006 | 231 | 2006 |
Concentration Dependent Cu2+ Induced Aggregation and Dityrosine Formation of the Alzheimer's Disease Amyloid-β Peptide DP Smith, GD Ciccotosto, DJ Tew, MT Fodero-Tavoletti, T Johanssen, ... Biochemistry 46 (10), 2881-2891, 2007 | 228 | 2007 |
Crystal structure of monomeric human β-2-microglobulin reveals clues to its amyloidogenic properties CH Trinh, DP Smith, AP Kalverda, SEV Phillips, SE Radford Proceedings of the National Academy of Sciences 99 (15), 9771-9776, 2002 | 222 | 2002 |
β2-microglobulin and its deamidated variant, N17D form amyloid fibrils with a range of morphologies in vitro NM Kad, NH Thomson, DP Smith, DA Smith, SE Radford Journal of molecular biology 313 (3), 559-571, 2001 | 222 | 2001 |
Elongated oligomers in β2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry DP Smith, SE Radford, AE Ashcroft Proceedings of the National Academy of Sciences 107 (15), 6794-6798, 2010 | 181 | 2010 |
In vitro characterization of Pittsburgh compound-B binding to Lewy bodies MT Fodero-Tavoletti, DP Smith, CA McLean, PA Adlard, KJ Barnham, ... Journal of Neuroscience 27 (39), 10365-10371, 2007 | 181 | 2007 |
A systematic investigation into the effect of protein destabilisation on beta 2-microglobulin amyloid formation DP Smith, S Jones, LC Serpell, M Sunde, SE Radford Journal of molecular biology 330 (5), 943-954, 2003 | 175 | 2003 |
Monitoring copopulated conformational states during protein folding events using electrospray ionization-ion mobility spectrometry-mass spectrometry DP Smith, K Giles, RH Bateman, SE Radford, AE Ashcroft Journal of the American Society for Mass Spectrometry 18, 2180-2190, 2007 | 161 | 2007 |
Stabilization of neurotoxic soluble β-sheet-rich conformations of the Alzheimer's disease amyloid-β peptide DJ Tew, SP Bottomley, DP Smith, GD Ciccotosto, J Babon, MG Hinds, ... Biophysical journal 94 (7), 2752-2766, 2008 | 126 | 2008 |
Role of the single disulphide bond of β2‐microglobulin in amyloidosis in vitro DP Smith, SE Radford Protein Science 10 (9), 1775-1784, 2001 | 90 | 2001 |
Formation of a high affinity lipid-binding intermediate during the early aggregation phase of α-synuclein DP Smith, DJ Tew, AF Hill, SP Bottomley, CL Masters, KJ Barnham, ... Biochemistry 47 (5), 1425-1434, 2008 | 76 | 2008 |
Linker histone H1 binds to disease associated amyloid-like fibrils JA Duce, DP Smith, RE Blake, PJ Crouch, QX Li, CL Masters, IA Trounce Journal of molecular biology 361 (3), 493-505, 2006 | 75 | 2006 |
Role of the N and C-terminal strands of beta 2-microglobulin in amyloid formation at neutral pH S Jones, DP Smith, SE Radford Journal of molecular biology 330 (5), 935-941, 2003 | 75 | 2003 |
Angiosarcoma of the small intestine: a case report and literature review. TN Chami, LE Ratner, J Henneberry, DP Smith, G Hill, PO Katz American Journal of Gastroenterology (Springer Nature) 89 (5), 1994 | 70 | 1994 |
Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson’s disease JA Duce, BX Wong, H Durham, JC Devedjian, DP Smith, D Devos Molecular neurodegeneration 12, 1-12, 2017 | 69 | 2017 |
Uncovering protein structure EJ Stollar, DP Smith Essays in biochemistry 64 (4), 649-680, 2020 | 68 | 2020 |