| Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ... Cell reports 32 (3), 2020 | 242 | 2020 |
| Patient-specific and genome-edited induced pluripotent stem cell–derived cardiomyocytes elucidate single-cell phenotype of Brugada syndrome P Liang, K Sallam, H Wu, Y Li, I Itzhaki, P Garg, Y Zhang, V Termglichan, ... Journal of the American College of Cardiology 68 (19), 2086-2096, 2016 | 220 | 2016 |
| Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle SA Goonasekera, CK Lam, DP Millay, MA Sargent, RJ Hajjar, EG Kranias, ... The Journal of clinical investigation 121 (3), 1044-1052, 2011 | 220 | 2011 |
| Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy J Lee, V Termglinchan, S Diecke, I Itzhaki, CK Lam, P Garg, E Lau, ... Nature 572 (7769), 335-340, 2019 | 158 | 2019 |
| Human-induced pluripotent stem cell model of trastuzumab-induced cardiac dysfunction in patients with breast cancer T Kitani, SG Ong, CK Lam, JW Rhee, JZ Zhang, A Oikonomopoulos, N Ma, ... Circulation 139 (21), 2451-2465, 2019 | 156 | 2019 |
| Determining the pathogenicity of a genomic variant of uncertain significance using CRISPR/Cas9 and human-induced pluripotent stem cells N Ma, JZ Zhang, I Itzhaki, SL Zhang, H Chen, F Haddad, T Kitani, ... Circulation 138 (23), 2666-2681, 2018 | 126 | 2018 |
| A human iPSC double-reporter system enables purification of cardiac lineage subpopulations with distinct function and drug response profiles JZ Zhang, V Termglinchan, NY Shao, I Itzhaki, C Liu, N Ma, L Tian, ... Cell Stem Cell 24 (5), 802-811. e5, 2019 | 119 | 2019 |
| Genome editing of induced pluripotent stem cells to decipher cardiac channelopathy variant P Garg, A Oikonomopoulos, H Chen, Y Li, CK Lam, K Sallam, M Perez, ... Journal of the American College of Cardiology 72 (1), 62-75, 2018 | 110 | 2018 |
| Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients H Wu, H Yang, JW Rhee, JZ Zhang, CK Lam, K Sallam, ACY Chang, ... European heart journal 40 (45), 3685-3695, 2019 | 106 | 2019 |
| A premature termination codon mutation in MYBPC3 causes hypertrophic cardiomyopathy via chronic activation of nonsense-mediated decay T Seeger, R Shrestha, CK Lam, C Chen, WL McKeithan, E Lau, ... Circulation 139 (6), 799-811, 2019 | 105 | 2019 |
| A novel human R25C-phospholamban mutation is associated with super-inhibition of calcium cycling and ventricular arrhythmia GS Liu, A Morales, E Vafiadaki, CK Lam, WF Cai, K Haghighi, G Adly, ... Cardiovascular research 107 (1), 164-174, 2015 | 96 | 2015 |
| Small heat shock protein 20 interacts with protein phosphatase-1 and enhances sarcoplasmic reticulum calcium cycling J Qian, E Vafiadaki, SM Florea, VP Singh, W Song, CK Lam, Y Wang, ... Circulation research 108 (12), 1429-1438, 2011 | 90 | 2011 |
| HAX-1 regulates cyclophilin-D levels and mitochondria permeability transition pore in the heart CK Lam, W Zhao, GS Liu, WF Cai, G Gardner, G Adly, EG Kranias Proceedings of the National Academy of Sciences 112 (47), E6466-E6475, 2015 | 73 | 2015 |
| Novel role of HAX-1 in ischemic injury protection involvement of heat shock protein 90 CK Lam, W Zhao, W Cai, E Vafiadaki, SM Florea, X Ren, Y Liu, N Robbins, ... Circulation research 112 (1), 79-89, 2013 | 73 | 2013 |
| Wnt10b gain-of-function improves cardiac repair by arteriole formation and attenuation of fibrosis DT Paik, M Rai, S Ryzhov, LN Sanders, O Aisagbonhi, MJ Funke, ... Circulation research 117 (9), 804-816, 2015 | 71 | 2015 |
| The anti-apoptotic protein HAX-1 is a regulator of cardiac function W Zhao, JR Waggoner, ZG Zhang, CK Lam, P Han, J Qian, PM Schroder, ... Proceedings of the National Academy of Sciences 106 (49), 20776-20781, 2009 | 69 | 2009 |
| Regulation of BECN1-mediated autophagy by HSPB6: Insights from a human HSPB6S10F mutant GS Liu, H Zhu, WF Cai, X Wang, M Jiang, K Essandoh, E Vafiadaki, ... Autophagy 14 (1), 80-97, 2018 | 35 | 2018 |
| Up‐regulation of micro‐RNA765 in human failing hearts is associated with post‐transcriptional regulation of protein phosphatase inhibitor‐1 and depressed contractility WF Cai, GS Liu, CK Lam, S Florea, J Qian, W Zhao, T Pritchard, ... European journal of heart failure 17 (8), 782-793, 2015 | 33 | 2015 |
| Modeling secondary iron overload cardiomyopathy with human induced pluripotent stem cell-derived cardiomyocytes JW Rhee, H Yi, D Thomas, CK Lam, N Belbachir, L Tian, X Qin, J Malisa, ... Cell reports 32 (2), 2020 | 30 | 2020 |
| Identifying the transcriptome signatures of calcium channel blockers in human induced pluripotent stem cell–derived cardiomyocytes CK Lam, L Tian, N Belbachir, A Wnorowski, R Shrestha, N Ma, T Kitani, ... Circulation research 125 (2), 212-222, 2019 | 30 | 2019 |
Joseph C. WuStanford University, Director, Cardiovascular Institute, Professor of Medicine & Radiology,Verified email at stanford.edu
