| Clearance prediction methodology needs fundamental improvement: trends common to rat and human hepatocytes/microsomes and implications for experimental methodology FL Wood, JB Houston, D Hallifax Drug Metabolism and Disposition 45 (11), 1178-1188, 2017 | 137 | 2017 |
| Importance of the unstirred water layer and hepatocyte membrane integrity in vitro for quantification of intrinsic metabolic clearance FL Wood, JB Houston, D Hallifax Drug Metabolism and Disposition 46 (3), 268-278, 2018 | 33 | 2018 |
| C8-substituted pyrido [3, 4-d] pyrimidin-4 (3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 … YV Le Bihan, RM Lanigan, B Atrash, MG McLaughlin, S Velupillai, ... European Journal of Medicinal Chemistry 177, 316-337, 2019 | 15 | 2019 |
| Metabolism of the dual FLT-3/Aurora kinase inhibitor CCT241736 in preclinical and human in vitro models: Implication for the choice of toxicology species FL Wood, S Shepherd, A Hayes, M Liu, K Grira, Y Mok, B Atrash, A Faisal, ... European Journal of Pharmaceutical Sciences 139, 104899, 2019 | 5 | 2019 |
| iTAG an optimized IMiD-induced degron for targeted protein degradation in human and murine cells H Bouguenina, S Nicolaou, YV Le Bihan, EA Bowling, C Calderon, ... Iscience 26 (7), 2023 | 2 | 2023 |
| Clearance prediction methodology needs fundamental improvement: trends common to rat and human hepatocytes/Microsomes and implications for experimental methodology (vol 45, pg … FL Wood, JB Houston, D Hallifax DRUG METABOLISM AND DISPOSITION 45 (12), 1239-1239, 2017 | 2* | 2017 |
| iTAG an optimized IMiD-induced degron for targeted protein degradation in human and murine cells H Bouguenina, S Nicolaou, YV Le Bihan, EA Bowling, C Calderon, ... Iscience 27 (5), 2024 | | 2024 |
| Optimisation of in Vitro Methodology for Drug Metabolism Studies to Improve Prediction of Hepatic Drug Clearance FL Wood PQDT-UK & Ireland, 2016 | | 2016 |
| Assessing metabolic competence in isolated hepatocytes: Exploring the relationship between enzyme function and plasma membrane integrity via Saponin treatment F Wood, D Hallifax, B Houston 13th European ISSX Meeting, 2015 | | 2015 |
| Intrinsic Clearance Predictions from Freshly Isolated Rat Hepatocytes: Effects of Assay Format and Cofactor Supplementation F Wood, D Hallifax, J Houston 20th International Symposium on Microsomes and Drug Oxidations (MDO), 2014 | | 2014 |
| Importance of the unstirred water layer and hepatocyte membrane integrity in vitro for FL Wood, JB Houston, D Hallifax | | |
