| Deacetylase inhibition promotes the generation and function of regulatory T cells R Tao, EF De Zoeten, E Özkaynak, C Chen, L Wang, PM Porrett, B Li, ... Nature medicine 13 (11), 1299-1307, 2007 | 1046 | 2007 |
| Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance Y Li, XC Li, XX Zheng, AD Wells, LA Turka, TB Strom Nature medicine 5 (11), 1298-1302, 1999 | 868 | 1999 |
| Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance AD Wells, XC Li, Y Li, MC Walsh, XX Zheng, Z Wu, G Nuñez, A Tang, ... Nature medicine 5 (11), 1303-1307, 1999 | 715 | 1999 |
| Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question EJ Suchin, PB Langmuir, E Palmer, MH Sayegh, AD Wells, LA Turka The Journal of Immunology 166 (2), 973-981, 2001 | 682 | 2001 |
| Distinct regulation of Th17 and Th1 cell differentiation by glutaminase-dependent metabolism MO Johnson, MM Wolf, MZ Madden, G Andrejeva, A Sugiura, ... Cell 175 (7), 1780-1795. e19, 2018 | 576 | 2018 |
| Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of … AD Wells, H Gudmundsdottir, LA Turka The Journal of clinical investigation 100 (12), 3173-3183, 1997 | 570 | 1997 |
| Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression VA Gerriets, RJ Kishton, MO Johnson, S Cohen, PJ Siska, AG Nichols, ... Nature immunology 17 (12), 1459-1466, 2016 | 509 | 2016 |
| Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor I Lee, L Wang, AD Wells, ME Dorf, E Ozkaynak, WW Hancock The Journal of experimental medicine 201 (7), 1037-1044, 2005 | 454 | 2005 |
| Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: effector function is linked to proliferative capacity H Gudmundsdottir, AD Wells, LA Turka The Journal of Immunology 162 (9), 5212-5223, 1999 | 351 | 1999 |
| The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo J Liu, T Miwa, B Hilliard, Y Chen, JD Lambris, AD Wells, WC Song The Journal of experimental medicine 201 (4), 567-577, 2005 | 294 | 2005 |
| Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation C Chen, EA Rowell, RM Thomas, WW Hancock, AD Wells Journal of Biological Chemistry 281 (48), 36828-36834, 2006 | 290 | 2006 |
| Notch signaling augments T cell responsiveness by enhancing CD25 expression SH Adler, E Chiffoleau, L Xu, NM Dalton, JM Burg, AD Wells, MS Wolfe, ... The Journal of Immunology 171 (6), 2896-2903, 2003 | 285 | 2003 |
| Epigenetic remodeling of the IL-2 and IFN-ã loci in memory CD8 T cells is influenced by CD4 T cells JK Northrop, RM Thomas, AD Wells, H Shen The Journal of Immunology 177 (2), 1062-1069, 2006 | 270 | 2006 |
| Signaling through CD28 and CTLA-4 controls two distinct forms of T cell anergy AD Wells, MC Walsh, JA Bluestone, LA Turka The Journal of clinical investigation 108 (6), 895-904, 2001 | 248 | 2001 |
| Heat shock proteins, tumor immunogenicity and antigen presentation: an integrated view AD Wells, M Malkovsky Immunology Today 21 (3), 129-132, 2000 | 241 | 2000 |
| T cell death and transplantation tolerance XC Li, TB Strom, LA Turka, AD Wells Immunity 14 (4), 407-416, 2001 | 232 | 2001 |
| Diversity and emerging roles of enhancer RNA in regulation of gene expression and cell fate PR Arnold, AD Wells, XC Li Frontiers in cell and developmental biology 7, 377, 2020 | 216 | 2020 |
| New insights into the molecular basis of T cell anergy: anergy factors, avoidance sensors, and epigenetic imprinting AD Wells The Journal of Immunology 182 (12), 7331-7341, 2009 | 195 | 2009 |
| BAFF binding to T cell‐expressed BAFF‐R costimulates T cell proliferation and alloresponses Q Ye, L Wang, AD Wells, R Tao, R Han, A Davidson, ML Scott, ... European journal of immunology 34 (10), 2750-2759, 2004 | 176 | 2004 |
| Hsp72-mediated augmentation of MHC class I surface expression and endogenous antigen presentation. AD Wells, SK Rai, MS Salvato, H Band, M Malkovsky International immunology 10 (5), 609-617, 1998 | 156 | 1998 |
Struan GrantProfessor of Genetics and PediatricsVerified email at pennmedicine.upenn.edu
