Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4 DL Guernsey, H Jiang, J Hussin, M Arnold, K Bouyakdan, S Perry, ... The American Journal of Human Genetics 87 (1), 40-51, 2010 | 248 | 2010 |
Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice B Davies, E Hatton, N Altemose, JG Hussin, F Pratto, G Zhang, AG Hinch, ... Nature 530 (7589), 171-176, 2016 | 231 | 2016 |
Recombination affects accumulation of damaging and disease-associated mutations in human populations JG Hussin, A Hodgkinson, Y Idaghdour, JC Grenier, JP Goulet, E Gbeha, ... Nature genetics 47 (4), 400-404, 2015 | 103 | 2015 |
Whole-exome sequencing reveals a rapid change in the frequency of rare functional variants in a founding population of humans F Casals, A Hodgkinson, J Hussin, Y Idaghdour, V Bruat, T de Maillard, ... PLoS genetics 9 (9), e1003815, 2013 | 103 | 2013 |
A population genetic approach to mapping neurological disorder genes using deep resequencing RA Myers, F Casals, J Gauthier, FF Hamdan, J Keebler, AR Boyko, ... PLoS genetics 7 (2), e1001318, 2011 | 103 | 2011 |
Diet networks: thin parameters for fat genomics A Romero, PL Carrier, A Erraqabi, T Sylvain, A Auvolat, E Dejoie, ... arXiv preprint arXiv:1611.09340, 2016 | 83 | 2016 |
Rare allelic forms of PRDM9 associated with childhood leukemogenesis J Hussin, D Sinnett, F Casals, Y Idaghdour, V Bruat, V Saillour, J Healy, ... Genome research 23 (3), 419-430, 2013 | 68 | 2013 |
Age-dependent recombination rates in human pedigrees J Hussin, MH Roy-Gagnon, R Gendron, G Andelfinger, P Awadalla PLoS genetics 7 (9), e1002251, 2011 | 68 | 2011 |
Plasmodium falciparum Genetic Diversity Maintained and Amplified Over 5 Years of a Low Transmission Endemic in the Peruvian Amazon OLH Branch, PL Sutton, C Barnes, JC Castro, J Hussin, P Awadalla, ... Molecular biology and evolution 28 (7), 1973-1986, 2011 | 66 | 2011 |
SARS–CoV-2 receptor ACE2 gene is associated with hypertension and severity of COVID 19: interaction with sex, obesity, and smoking P Hamet, Z Pausova, R Attaoua, C Hishmih, M Haloui, J Shin, T Paus, ... American journal of hypertension 34 (4), 367-376, 2021 | 60 | 2021 |
Multiscale PHATE identifies multimodal signatures of COVID-19 M Kuchroo, J Huang, P Wong, JC Grenier, D Shung, A Tong, C Lucas, ... Nature biotechnology 40 (5), 681-691, 2022 | 57 | 2022 |
The impact of recombination on human mutation load and disease I Alves, AA Houle, JG Hussin, P Awadalla Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017 | 40 | 2017 |
Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control J Tremblay, M Haloui, R Attaoua, R Tahir, C Hishmih, F Harvey, ... Diabetologia 64, 2012-2025, 2021 | 37 | 2021 |
Multicohort analysis of the maternal age effect on recombination HC Martin, R Christ, JG Hussin, J O¢Connell, S Gordon, H Mbarek, ... Nature Communications 6 (1), 7846, 2015 | 37 | 2015 |
Next-generation sequencing approaches for genetic mapping of complex diseases F Casals, Y Idaghdour, J Hussin, P Awadalla Journal of neuroimmunology 248 (1-2), 10-22, 2012 | 36 | 2012 |
Insights into platypus population structure and history from whole-genome sequencing HC Martin, EM Batty, J Hussin, P Westall, T Daish, S Kolomyjec, P Piazza, ... Molecular Biology and Evolution 35 (5), 1238-1252, 2018 | 35 | 2018 |
The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent manner DJ Hamelin, D Fournelle, JC Grenier, J Schockaert, KA Kovalchik, ... Cell systems 13 (2), 143-157. e3, 2022 | 28 | 2022 |
Haplotype allelic classes for detecting ongoing positive selection J Hussin, P Nadeau, JF Lefebvre, D Labuda BMC bioinformatics 11, 1-11, 2010 | 27 | 2010 |
A family-based probabilistic method for capturing de novo mutations from high-throughput short-read sequencing data RA Cartwright, J Hussin, JEM Keebler, EA Stone, P Awadalla Statistical applications in genetics and molecular biology 11 (2), 2012 | 26 | 2012 |
Implementing machine learning in interventional cardiology: the benefits are worth the trouble W Ben Ali, A Pesaranghader, R Avram, P Overtchouk, N Perrin, S Laffite, ... Frontiers in Cardiovascular Medicine 8, 711401, 2021 | 24 | 2021 |