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Bora Gurel
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Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
MC Haffner, MJ Aryee, A Toubaji, DM Esopi, R Albadine, B Gurel, ...
Nature genetics 42 (8), 668-675, 2010
6732010
Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial
J Mateo, N Porta, D Bianchini, U McGovern, T Elliott, R Jones, I Syndikus, ...
The Lancet Oncology 21 (1), 162-174, 2020
5462020
Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis
B Gurel, T Iwata, CM Koh, RB Jenkins, F Lan, C Van Dang, JL Hicks, ...
Modern Pathology 21 (9), 1156-1167, 2008
4892008
PTEN protein loss by immunostaining: Analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients
TL Lotan, B Gurel, S Sutcliffe, D Esopi, W Liu, J Xu, JL Hicks, BH Park, ...
Clinical Cancer Research 17 (20), 6563-6573, 2011
3842011
DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity
S Yegnasubramanian, MC Haffner, Y Zhang, B Gurel, TC Cornish, Z Wu, ...
Cancer research 68 (21), 8954-8967, 2008
3382008
Prostate-specific Membrane Antigen Heterogeneity and DNA Repair Defects in Prostate Cancer
A Paschalis, B Sheehan, R Riisnaes, DN Rodrigues, B Gurel, C Bertan, ...
European Urology, 2019
3282019
NKX3. 1 as a marker of prostatic origin in metastatic tumors
B Gurel, TZ Ali, EA Montgomery, S Begum, J Hicks, M Goggins, ...
The American journal of surgical pathology 34 (8), 1097-1105, 2010
3112010
Chronic Inflammation in Benign Prostate Tissue Is Associated with High-Grade Prostate Cancer in the Placebo Arm of the Prostate Cancer Prevention Trial
B Gurel, MS Lucia, IM Thompson, PJ Goodman, CM Tangen, AR Kristal, ...
Cancer Epidemiology Biomarkers & Prevention 23 (5), 847-856, 2014
2742014
Engineering a Prostate-Specific Membrane Antigen–Activated Tumor Endothelial Cell Prodrug for Cancer Therapy
SR Denmeade, AM Mhaka, DM Rosen, WN Brennen, S Dalrymple, I Dach, ...
Science translational medicine 4 (140), 140ra86-140ra86, 2012
2512012
Genomics of lethal prostate cancer at diagnosis and castration resistance
J Mateo, G Seed, C Bertan, P Rescigno, D Dolling, I Figueiredo, ...
The Journal of clinical investigation 130 (4), 1743-1751, 2020
2182020
Prostate carcinogenesis: inflammatory storms
JS de Bono, C Guo, B Gurel, AM De Marzo, KS Sfanos, RS Mani, J Gil, ...
Nature Reviews Cancer 20 (8), 455-469, 2020
1322020
Alterations in nucleolar structure and gene expression programs in prostatic neoplasia are driven by the MYC oncogene
CM Koh, B Gurel, S Sutcliffe, MJ Aryee, D Schultz, T Iwata, M Uemura, ...
The American journal of pathology 178 (4), 1824-1834, 2011
1322011
Targeting the p300/CBP axis in lethal prostate cancer
J Welti, A Sharp, N Brooks, W Yuan, C McNair, SN Chand, A Pal, ...
Cancer Discovery 11 (5), 1118-1137, 2021
1312021
Preventive effect of aminoguanidine compared to vitamin E and C on cisplatin-induced nephrotoxicity in rats
S Atasayar, H Gürer-Orhan, H Orhan, B Gürel, G Girgin, H Özgüneş
Experimental and Toxicologic Pathology 61 (1), 23-32, 2009
1262009
An immunohistochemical signature comprising PTEN, MYC, and Ki67 predicts progression in prostate cancer patients receiving adjuvant docetaxel after prostatectomy
ES Antonarakis, D Keizman, Z Zhang, B Gurel, TL Lotan, JL Hicks, ...
Cancer 118 (24), 6063-6071, 2012
1162012
Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular colonization
MC Haffner, C Weier, MM Xu, A Vaghasia, B Gürel, B Gümüşkaya, ...
The Journal of pathology 238 (1), 31-41, 2016
1022016
Loss of Nkx3. 1 expression in bacterial prostatitis: a potential link between inflammation and neoplasia
M Khalili, LN Mutton, B Gurel, JL Hicks, AM De Marzo, CJ Bieberich
The American journal of pathology 176 (5), 2259-2268, 2010
942010
Molecular alterations in prostate cancer as diagnostic, prognostic, and therapeutic targets.
B Gurel, T Iwata, CM Koh, S Yegnasubramanian, WG Nelson, ...
Advances in anatomic pathology 15 (6), 319-331, 2008
942008
High expression of prostate-specific membrane antigen in the tumor-associated neo-vasculature is associated with worse prognosis in squamous cell carcinoma of the oral cavity
MC Haffner, J Laimer, A Chaux, G Schäfer, P Obrist, A Brunner, ...
Modern Pathology 25 (8), 1079-1085, 2012
882012
Biomarkers associating with PARP inhibitor benefit in prostate cancer in the TOPARP-B trial
S Carreira, N Porta, S Arce-Gallego, G Seed, A Llop-Guevara, D Bianchini, ...
Cancer discovery 11 (11), 2812-2827, 2021
862021
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