Stephen J. Haggarty, PhD
Stephen J. Haggarty, PhD
Harvard Medical School, MGH
Verified email at - Homepage
Cited by
Cited by
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease
J Lamb, ED Crawford, D Peck, JW Modell, IC Blat, MJ Wrobel, J Lerner, ...
science 313 (5795), 1929-1935, 2006
A next generation connectivity map: L1000 platform and the first 1,000,000 profiles
A Subramanian, R Narayan, SM Corsello, DD Peck, TE Natoli, X Lu, ...
Cell 171 (6), 1437-1452. e17, 2017
Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen
TU Mayer, TM Kapoor, SJ Haggarty, RW King, SL Schreiber, TJ Mitchison
Science 286 (5441), 971-974, 1999
HDAC2 negatively regulates memory formation and synaptic plasticity
JS Guan, SJ Haggarty, E Giacometti, JH Dannenberg, N Joseph, J Gao, ...
Nature 459 (7243), 55-60, 2009
A polygenic burden of rare disruptive mutations in schizophrenia
SM Purcell, JL Moran, M Fromer, D Ruderfer, N Solovieff, P Roussos, ...
Nature 506 (7487), 185-190, 2014
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
SJ Haggarty, KM Koeller, JC Wong, CM Grozinger, SL Schreiber
Proceedings of the National Academy of Sciences 100 (8), 4389-4394, 2003
An epigenetic blockade of cognitive functions in the neurodegenerating brain
J Gräff, D Rei, JS Guan, WY Wang, J Seo, KM Hennig, TJF Nieland, ...
Nature 483 (7388), 222-226, 2012
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3β/β-catenin signaling
Y Mao, X Ge, CL Frank, JM Madison, AN Koehler, MK Doud, C Tassa, ...
Cell 136 (6), 1017-1031, 2009
Chemical phylogenetics of histone deacetylases
JE Bradner, N West, ML Grachan, EF Greenberg, SJ Haggarty, T Warnow, ...
Nature chemical biology 6 (3), 238-243, 2010
Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease
M Kilgore, CA Miller, DM Fass, KM Hennig, SJ Haggarty, JD Sweatt, ...
Neuropsychopharmacology 35 (4), 870-880, 2010
Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation
J Rihel, DA Prober, A Arvanites, K Lam, S Zimmerman, S Jang, ...
Science 327 (5963), 348-351, 2010
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
I Maze, HE Covington III, DM Dietz, Q LaPlant, W Renthal, SJ Russo, ...
Science 327 (5962), 213-216, 2010
Antidepressant actions of histone deacetylase inhibitors
HE Covington, I Maze, QC LaPlant, VF Vialou, YN Ohnishi, O Berton, ...
Journal of Neuroscience 29 (37), 11451-11460, 2009
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli
W Renthal, I Maze, V Krishnan, HE Covington, G Xiao, A Kumar, ...
Neuron 56 (3), 517-529, 2007
Rapid behavior-based identification of neuroactive small molecules in the zebrafish
D Kokel, J Bryan, C Laggner, R White, CYJ Cheung, R Mateus, D Healey, ...
Nature chemical biology 6 (3), 231-237, 2010
Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis
SJ Haggarty, TU Mayer, DT Miyamoto, R Fathi, RW King, TJ Mitchison, ...
Chemistry & biology 7 (4), 275-286, 2000
Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories
J Gräff, NF Joseph, ME Horn, A Samiei, J Meng, J Seo, D Rei, AW Bero, ...
Cell 156 (1), 261-276, 2014
CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors
A Sugathan, M Biagioli, C Golzio, S Erdin, I Blumenthal, P Manavalan, ...
Proceedings of the National Academy of Sciences 111 (42), E4468-E4477, 2014
Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome
SD Sheridan, KM Theriault, SA Reis, F Zhou, JM Madison, L Daheron, ...
PloS one 6 (10), e26203, 2011
Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity
D Kim, CL Frank, MM Dobbin, RK Tsunemoto, W Tu, PL Peng, JS Guan, ...
Neuron 60 (5), 803-817, 2008
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