Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma S Gayle, S Landrette, N Beeharry, C Conrad, M Hernandez, P Beckett, ... Blood, The Journal of the American Society of Hematology 129 (13), 1768-1778, 2017 | 173 | 2017 |
A modified HSP70 inhibitor shows broad activity as an anticancer agent GM Balaburski, JIJ Leu, N Beeharry, S Hayik, MD Andrake, G Zhang, ... Molecular Cancer Research 11 (3), 219-229, 2013 | 116 | 2013 |
Linoleic acid and antioxidants protect against DNA damage and apoptosis induced by palmitic acid N Beeharry, JE Lowe, AR Hernandez, JA Chambers, F Fucassi, PJ Cragg, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 530 (1 …, 2003 | 111 | 2003 |
HuR posttranscriptionally regulates WEE1: implications for the DNA damage response in pancreatic cancer cells S Lal, RA Burkhart, N Beeharry, V Bhattacharjee, ER Londin, ... Cancer research 74 (4), 1128-1140, 2014 | 110 | 2014 |
Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence Z Tu, KM Aird, BG Bitler, JP Nicodemus, N Beeharry, B Xia, TJ Yen, ... Developmental cell 21 (6), 1077-1091, 2011 | 99 | 2011 |
Fatty acid protection from palmitic acid-induced apoptosis is lost following PI3-kinase inhibition N Beeharry, JA Chambers, IC Green Apoptosis 9, 599-607, 2004 | 93 | 2004 |
Cytokines and nitric oxide inhibit the enzyme activity of catalase but not its protein or mRNA expression in insulin-producing cells LA Sigfrid, JM Cunningham, N Beeharry, S Lortz, M Tiedge, S Lenzen, ... Journal of molecular endocrinology 31 (3), 509-518, 2003 | 76 | 2003 |
Comparison of the activity of three different HSP70 inhibitors on apoptosis, cell cycle arrest, autophagy inhibition, and HSP90 inhibition A Budina-Kolomets, GM Balaburski, A Bondar, N Beeharry, T Yen, ... Cancer biology & therapy 15 (2), 194-199, 2014 | 57 | 2014 |
Thymine DNA glycosylase as a novel target for melanoma P Mancuso, R Tricarico, V Bhattacharjee, L Cosentino, Y Kadariya, ... Oncogene 38 (19), 3710-3728, 2019 | 47 | 2019 |
Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint H Huang, L Fletcher, N Beeharry, R Daniel, G Kao, TJ Yen, RJ Muschel Cancer research 68 (10), 3724-3732, 2008 | 46 | 2008 |
G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression AM Michal, CH So, N Beeharry, H Shankar, R Mashayekhi, TJ Yen, ... Journal of Biological Chemistry 287 (9), 6928-6940, 2012 | 45 | 2012 |
Antioxidant enzyme activity and mRNA expression in the islets of Langerhans from the BB/S rat model of type 1 diabetes and an insulin-producing cell line LA Sigfrid, JM Cunningham, N Beeharry, LA Håkan Borg, ... Journal of molecular medicine 82, 325-335, 2004 | 44 | 2004 |
DUSP6 regulates drug sensitivity by modulating DNA damage response TV Bagnyukova, D Restifo, N Beeharry, L Gabitova, T Li, IG Serebriiskii, ... British journal of cancer 109 (4), 1063-1071, 2013 | 40 | 2013 |
Targeting WEE1 to enhance conventional therapies for acute lymphoblastic leukemia A Ghelli Luserna Di Rorà, N Beeharry, E Imbrogno, A Ferrari, V Robustelli, ... Journal of hematology & oncology 11, 1-18, 2018 | 39 | 2018 |
Dose dependent effects on cell cycle checkpoints and DNA repair by bendamustine N Beeharry, JB Rattner, A Bellacosa, MR Smith, TJ Yen PloS one 7 (6), e40342, 2012 | 36 | 2012 |
Telomere dynamics in response to chemotherapy N Beeharry, D Broccoli Current molecular medicine 5 (2), 187-196, 2005 | 33 | 2005 |
Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission MK Martz, E Grabocka, N Beeharry, TJ Yen, PB Wedegaertner Molecular biology of the cell 24 (18), 2785-2794, 2013 | 32 | 2013 |
Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death V Ratushny, HB Pathak, N Beeharry, N Tikhmyanova, F Xiao, T Li, ... Oncogene 31 (10), 1217-1227, 2012 | 32 | 2012 |
Centromere fragmentation is a common mitotic defect of S and G2 checkpoint override N Beeharry, J Rattner, J Caviston, T Yen Cell cycle 12 (10), 1588-1597, 2013 | 30 | 2013 |
Pixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions N Beeharry, AGL Di Rora, MR Smith, TJ Yen Cancer biology & therapy 16 (9), 1397-1406, 2015 | 23 | 2015 |