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Jason A. Hackney
Jason A. Hackney
Distinguished Scientist, Genentech, Inc.
Verified email at gene.com
Title
Cited by
Cited by
Year
A stem cell molecular signature
NB Ivanova, JT Dimos, C Schaniel, JA Hackney, KA Moore, IR Lemischka
Science 298 (5593), 601-604, 2002
18392002
The immunoreceptor TIGIT regulates antitumor and antiviral CD8+ T cell effector function
RJ Johnston, L Comps-Agrar, J Hackney, X Yu, M Huseni, Y Yang, S Park, ...
Cancer cell 26 (6), 923-937, 2014
10912014
Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
R Bueno, EW Stawiski, LD Goldstein, S Durinck, A De Rienzo, ...
Nature genetics 48 (4), 407-416, 2016
8152016
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner
V Ramirez-Carrozzi, A Sambandam, E Luis, Z Lin, S Jeet, J Lesch, ...
Nature immunology 12 (12), 1159-1166, 2011
5012011
A genomic regulatory element that directs assembly and function of immune-specific AP-1–IRF complexes
E Glasmacher, S Agrawal, AB Chang, TL Murphy, W Zeng, B Vander Lugt, ...
Science 338 (6109), 975-980, 2012
3662012
Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics
G Dennis, CTJ Holweg, SK Kummerfeld, DF Choy, AF Setiadi, ...
Arthritis research & therapy 16, 1-18, 2014
3602014
Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation
B Vander Lugt, AA Khan, JA Hackney, S Agrawal, J Lesch, M Zhou, ...
Nature immunology 15 (2), 161-167, 2014
2882014
A molecular profile of a hematopoietic stem cell niche
JA Hackney, P Charbord, BP Brunk, CJ Stoeckert, IR Lemischka, ...
Proceedings of the National Academy of Sciences 99 (20), 13061-13066, 2002
2882002
Molecular portraits of early rheumatoid arthritis identify clinical and treatment response phenotypes
MJ Lewis, MR Barnes, K Blighe, K Goldmann, S Rana, JA Hackney, ...
Cell reports 28 (9), 2455-2470. e5, 2019
2792019
Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients
F Humby, M Lewis, N Ramamoorthi, JA Hackney, MR Barnes, ...
Annals of the rheumatic diseases 78 (6), 761-772, 2019
2502019
Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells
S Rutz, R Noubade, C Eidenschenk, N Ota, W Zeng, Y Zheng, J Hackney, ...
Nature immunology 12 (12), 1238-1245, 2011
2322011
NRROS negatively regulates reactive oxygen species during host defence and autoimmunity
R Noubade, K Wong, N Ota, S Rutz, C Eidenschenk, PA Valdez, J Ding, ...
Nature 509 (7499), 235-239, 2014
2262014
Association between response to etrolizumab and expression of integrin αE and granzyme A in colon biopsies of patients with ulcerative colitis
GW Tew, JA Hackney, D Gibbons, CA Lamb, D Luca, JG Egen, L Diehl, ...
Gastroenterology 150 (2), 477-487. e9, 2016
1622016
Integration of eQTL and a single-cell atlas in the human eye identifies causal genes for age-related macular degeneration
LD Orozco, HH Chen, C Cox, KJ Katschke, R Arceo, C Espiritu, P Caplazi, ...
Cell reports 30 (4), 1246-1259. e6, 2020
1602020
c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis
C Neumann, J Blume, U Roy, PP Teh, A Vasanthakumar, A Beller, Y Liao, ...
Nature immunology 20 (4), 471-481, 2019
1552019
Identification of developmentally regulated genes in Entamoeba histolytica: insights into mechanisms of stage conversion in a protozoan parasite
GM Ehrenkaufer, R Haque, JA Hackney, DJ Eichinger, U Singh
Cellular microbiology 9 (6), 1426-1444, 2007
1552007
Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q
S Pidasheva, S Trifari, A Phillips, JA Hackney, Y Ma, A Smith, SJ Sohn, ...
PloS one 6 (10), e25038, 2011
1372011
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus
HD Brightbill, E Suto, N Blaquiere, N Ramamoorthi, S Sujatha-Bhaskar, ...
Nature communications 9 (1), 179, 2018
1112018
Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling
M Samie, J Lim, E Verschueren, JM Baughman, I Peng, A Wong, Y Kwon, ...
Nature immunology 19 (3), 246-254, 2018
1042018
Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent …
G Lliso-Ribera, F Humby, M Lewis, A Nerviani, D Mauro, F Rivellese, ...
Annals of the rheumatic diseases 78 (12), 1642-1652, 2019
952019
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