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Deepa Ajit
Deepa Ajit
Verified email at neurology.unc.edu
Title
Cited by
Cited by
Year
Toll‐like receptors 2 and 4 mediate Aβ (1–42) activation of the innate immune response in a human monocytic cell line
MLD Udan, D Ajit, NR Crouse, MR Nichols
Journal of neurochemistry 104 (2), 524-533, 2008
2242008
Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA2-IIA expression in astrocytes …
W Sheng, Y Zong, A Mohammad, D Ajit, J Cui, D Han, JL Hamilton, ...
Journal of neuroinflammation 8, 1-15, 2011
1772011
Beneficial effects of dietary EGCG and voluntary exercise on behavior in an Alzheimer's disease mouse model
JM Walker, D Klakotskaia, D Ajit, GA Weisman, WG Wood, GY Sun, ...
Journal of Alzheimer's disease 44 (2), 561-572, 2015
1422015
Purinergic receptors as potential therapeutic targets in Alzheimer's disease
LT Woods, D Ajit, JM Camden, L Erb, GA Weisman
Neuropharmacology 104, 169-179, 2016
1082016
P2 Receptors for Extracellular Nucleotides in the Central Nervous System: Role of P2X7 and P2Y2 Receptor Interactions in Neuroinflammation
GA Weisman, JM Camden, TS Peterson, D Ajit, LT Woods, L Erb
Molecular neurobiology 46, 96-113, 2012
1022012
Nucleotides released from Aβ1–42‐treated microglial cells increase cell migration and Aβ1–42 uptake through P2Y2 receptor activation
HJ Kim, D Ajit, TS Peterson, Y Wang, JM Camden, W Gibson Wood, ...
Journal of neurochemistry 121 (2), 228-238, 2012
772012
The deacetylase HDAC6 mediates endogenous neuritic tau pathology
JH Tseng, L Xie, S Song, Y Xie, L Allen, D Ajit, JS Hong, X Chen, ...
Cell reports 20 (9), 2169-2183, 2017
662017
Loss of P2Y2 Nucleotide Receptors Enhances Early Pathology in the TgCRND8 Mouse Model of Alzheimer's Disease
D Ajit, LT Woods, JM Camden, CN Thebeau, FG El-Sayed, GW Greeson, ...
Molecular neurobiology 49, 1031-1042, 2014
662014
An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline
H Trzeciakiewicz, D Ajit, JH Tseng, Y Chen, A Ajit, Z Tabassum, ...
Nature communications 11 (1), 5522, 2020
652020
Neuroprotective roles of the P2Y2 receptor
GA Weisman, D Ajit, R Garrad, TS Peterson, LT Woods, C Thebeau, ...
Purinergic signalling 8, 559-578, 2012
652012
Phytochemicals and botanical extracts regulate NF-κB and Nrf2/ARE reporter activities in DI TNC1 astrocytes
D Ajit, A Simonyi, R Li, Z Chen, M Hannink, KL Fritsche, VV Mossine, ...
Neurochemistry international 97, 49-56, 2016
522016
Up‐regulation and activation of the P2Y2 nucleotide receptor mediate neurite extension in IL‐1β‐treated mouse primary cortical neurons
TS Peterson, CN Thebeau, D Ajit, JM Camden, LT Woods, WG Wood, ...
Journal of neurochemistry 125 (6), 885-896, 2013
482013
P2Y receptors in Alzheimer's disease
L Erb, C Cao, D Ajit, GA Weisman
Biology of the Cell 107 (1), 1-21, 2015
472015
Oligomeric amyloid-β (1–42) induces THP-1 human monocyte adhesion and maturation
NR Crouse, D Ajit, MLD Udan, MR Nichols
Brain research 1254, 109-119, 2009
462009
Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome
MA Cousin, BA Creighton, KA Breau, RC Spillmann, E Torti, S Dontu, ...
Nature genetics 53 (7), 1006-1021, 2021
432021
Amyloid-β (1− 42) fibrillar precursors are optimal for inducing tumor necrosis factor-α production in the THP-1 human monocytic cell line
D Ajit, MLD Udan, G Paranjape, MR Nichols
Biochemistry 48 (38), 9011-9021, 2009
332009
Probing the amyloid-β (1–40) fibril environment with substituted tryptophan residues
JC Touchette, LL Williams, D Ajit, F Gallazzi, MR Nichols
Archives of biochemistry and biophysics 494 (2), 192-197, 2010
202010
DIFFERENT AMYLOID-ENT AMYLOID-beta AGGREGATION STATES INDUCE MONOCYTE DIFFERENTIATION OR ACTIVATION
MR Nichols, N Crouse, D Ajit, G Paranjape, M Udan
Journal of Neurochemistry 108, 67-67, 2009
162009
Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A
BA Creighton, S Afriyie, D Ajit, CR Casingal, KM Voos, J Reger, AM Burch, ...
Elife 10, e69815, 2021
142021
A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation
D Ajit, H Trzeciakiewicz, JH Tseng, CM Wander, Y Chen, A Ajit, DP King, ...
Journal of Biological Chemistry 294 (45), 16698-16711, 2019
142019
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