Toll‐like receptors 2 and 4 mediate Aβ (1–42) activation of the innate immune response in a human monocytic cell line MLD Udan, D Ajit, NR Crouse, MR Nichols Journal of neurochemistry 104 (2), 524-533, 2008 | 224 | 2008 |
Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA2-IIA expression in astrocytes … W Sheng, Y Zong, A Mohammad, D Ajit, J Cui, D Han, JL Hamilton, ... Journal of neuroinflammation 8, 1-15, 2011 | 177 | 2011 |
Beneficial effects of dietary EGCG and voluntary exercise on behavior in an Alzheimer's disease mouse model JM Walker, D Klakotskaia, D Ajit, GA Weisman, WG Wood, GY Sun, ... Journal of Alzheimer's disease 44 (2), 561-572, 2015 | 142 | 2015 |
Purinergic receptors as potential therapeutic targets in Alzheimer's disease LT Woods, D Ajit, JM Camden, L Erb, GA Weisman Neuropharmacology 104, 169-179, 2016 | 108 | 2016 |
P2 Receptors for Extracellular Nucleotides in the Central Nervous System: Role of P2X7 and P2Y2 Receptor Interactions in Neuroinflammation GA Weisman, JM Camden, TS Peterson, D Ajit, LT Woods, L Erb Molecular neurobiology 46, 96-113, 2012 | 102 | 2012 |
Nucleotides released from Aβ1–42‐treated microglial cells increase cell migration and Aβ1–42 uptake through P2Y2 receptor activation HJ Kim, D Ajit, TS Peterson, Y Wang, JM Camden, W Gibson Wood, ... Journal of neurochemistry 121 (2), 228-238, 2012 | 77 | 2012 |
The deacetylase HDAC6 mediates endogenous neuritic tau pathology JH Tseng, L Xie, S Song, Y Xie, L Allen, D Ajit, JS Hong, X Chen, ... Cell reports 20 (9), 2169-2183, 2017 | 66 | 2017 |
Loss of P2Y2 Nucleotide Receptors Enhances Early Pathology in the TgCRND8 Mouse Model of Alzheimer's Disease D Ajit, LT Woods, JM Camden, CN Thebeau, FG El-Sayed, GW Greeson, ... Molecular neurobiology 49, 1031-1042, 2014 | 66 | 2014 |
An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline H Trzeciakiewicz, D Ajit, JH Tseng, Y Chen, A Ajit, Z Tabassum, ... Nature communications 11 (1), 5522, 2020 | 65 | 2020 |
Neuroprotective roles of the P2Y2 receptor GA Weisman, D Ajit, R Garrad, TS Peterson, LT Woods, C Thebeau, ... Purinergic signalling 8, 559-578, 2012 | 65 | 2012 |
Phytochemicals and botanical extracts regulate NF-κB and Nrf2/ARE reporter activities in DI TNC1 astrocytes D Ajit, A Simonyi, R Li, Z Chen, M Hannink, KL Fritsche, VV Mossine, ... Neurochemistry international 97, 49-56, 2016 | 52 | 2016 |
Up‐regulation and activation of the P2Y2 nucleotide receptor mediate neurite extension in IL‐1β‐treated mouse primary cortical neurons TS Peterson, CN Thebeau, D Ajit, JM Camden, LT Woods, WG Wood, ... Journal of neurochemistry 125 (6), 885-896, 2013 | 48 | 2013 |
P2Y receptors in Alzheimer's disease L Erb, C Cao, D Ajit, GA Weisman Biology of the Cell 107 (1), 1-21, 2015 | 47 | 2015 |
Oligomeric amyloid-β (1–42) induces THP-1 human monocyte adhesion and maturation NR Crouse, D Ajit, MLD Udan, MR Nichols Brain research 1254, 109-119, 2009 | 46 | 2009 |
Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome MA Cousin, BA Creighton, KA Breau, RC Spillmann, E Torti, S Dontu, ... Nature genetics 53 (7), 1006-1021, 2021 | 43 | 2021 |
Amyloid-β (1− 42) fibrillar precursors are optimal for inducing tumor necrosis factor-α production in the THP-1 human monocytic cell line D Ajit, MLD Udan, G Paranjape, MR Nichols Biochemistry 48 (38), 9011-9021, 2009 | 33 | 2009 |
Probing the amyloid-β (1–40) fibril environment with substituted tryptophan residues JC Touchette, LL Williams, D Ajit, F Gallazzi, MR Nichols Archives of biochemistry and biophysics 494 (2), 192-197, 2010 | 20 | 2010 |
DIFFERENT AMYLOID-ENT AMYLOID-beta AGGREGATION STATES INDUCE MONOCYTE DIFFERENTIATION OR ACTIVATION MR Nichols, N Crouse, D Ajit, G Paranjape, M Udan Journal of Neurochemistry 108, 67-67, 2009 | 16 | 2009 |
Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A BA Creighton, S Afriyie, D Ajit, CR Casingal, KM Voos, J Reger, AM Burch, ... Elife 10, e69815, 2021 | 14 | 2021 |
A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation D Ajit, H Trzeciakiewicz, JH Tseng, CM Wander, Y Chen, A Ajit, DP King, ... Journal of Biological Chemistry 294 (45), 16698-16711, 2019 | 14 | 2019 |