| An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1 KD Konze, A Ma, F Li, D Barsyte-Lovejoy, T Parton, CJ MacNevin, F Liu, ... ACS chemical biology 8 (6), 1324-1334, 2013 | 479 | 2013 |
| Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia B Xu, DM On, A Ma, T Parton, KD Konze, SG Pattenden, DF Allison, L Cai, ... Blood, The Journal of the American Society of Hematology 125 (2), 346-357, 2015 | 234 | 2015 |
| Selective inhibitors of protein methyltransferases HU Kaniskan, KD Konze, J Jin Journal of medicinal chemistry 58 (4), 1596-1629, 2015 | 134 | 2015 |
| Targeting EZH2 and PRC2 dependence as novel anticancer therapy B Xu, KD Konze, J Jin, GG Wang Experimental hematology 43 (8), 698-712, 2015 | 120 | 2015 |
| Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent … KD Konze, PH Bos, MK Dahlgren, K Leswing, I Tubert-Brohman, ... Journal of chemical information and modeling 59 (9), 3782-3793, 2019 | 103 | 2019 |
| Structure–Activity Relationship Studies for Enhancer of Zeste Homologue 2 (EZH2) and Enhancer of Zeste Homologue 1 (EZH1) Inhibitors X Yang, F Li, KD Konze, J Meslamani, A Ma, PJ Brown, MM Zhou, ... Journal of medicinal chemistry 59 (16), 7617-7633, 2016 | 55 | 2016 |
| Polycomb genes, miRNA, and their deregulation in B-cell malignancies GG Wang, KD Konze, J Tao Blood, The Journal of the American Society of Hematology 125 (8), 1217-1225, 2015 | 53 | 2015 |
| Combining Cloud-Based Free-Energy Calculations, Synthetically Aware Enumerations, and Goal-Directed Generative Machine Learning for Rapid Large-Scale Chemical Exploration and … P Ghanakota, PH Bos, KD Konze, J Staker, G Marques, K Marshall, ... Journal of Chemical Information and Modeling 60 (9), 4311-4325, 2020 | 35 | 2020 |
| A chemical tool for in vitro and in vivo precipitation of lysine methyltransferase G9a KD Konze, SG Pattenden, F Liu, D Barsyte‐Lovejoy, F Li, JM Simon, ... ChemMedChem 9 (3), 549-553, 2014 | 33 | 2014 |
| Inhibitors of (alpha-v)(beta-6) integrin BA Harrison, MG Bursavich, M Brewer, AI Gerasyuto, KN Hahn, KD Konze, ... US Patent App. 15/906,745, 2018 | 17 | 2018 |
| Inhibiting (alpha-v)(beta-6) integrin BA Harrison, JE Dowling, MG Bursavich, DM Troast, BS Lippa, BN Rogers, ... US Patent App. 16/555,589, 2020 | 7 | 2020 |
| Inhibitors of (α-v)(β-6) integrin BA Harrison, MG Bursavich, M Brewer, AI Gerasyuto, KN Hahn, KD Konze, ... US Patent 11,046,669, 2021 | 6 | 2021 |
| Inhibitors of (α-v)(β-6) integrin BA Harrison, MG Bursavich, AI Gerasyuto, KN Hahn, KD Konze, FY Lin, ... US Patent 11,046,685, 2021 | 6 | 2021 |
| Inhibitors of (alpha-v)(beta-6) integrin M Brewer, MG Bursavich, AI Gerasyuto, KN Hahn, BA Harrison, KD Konze, ... US Patent 11,040,955, 2021 | 6 | 2021 |
| Inhibiting (alpha-v)(beta-6) integrin BA Harrison, JE Dowling, MG Bursavich, DM Troast, BS Lippa, BN Rogers, ... US Patent App. 16/939,848, 2020 | 6 | 2020 |
| Multi-omic Dissection of Oncogenically Active Epiproteomes Identifies Drivers of Proliferative and Invasive Breast Tumors JA Wrobel, L Xie, L Wang, C Liu, N Rashid, KK Gallagher, Y Xiong, ... iScience 17, 359-378, 2019 | 6 | 2019 |
| Shp2 phosphatase inhibitors and methods of use thereof WP Walters, A Lescarbeau, EH Kelley, KC Shortsleeves, AM Taylor, ... US Patent App. 16/971,435, 2020 | 5 | 2020 |
| Antagonists of human integrin α4β7 MG Bursavich, DM Troast, BA Harrison, BS Lippa, BN Rogers, KD Konze, ... US Patent 10,759,756, 2020 | 4 | 2020 |
| Inhibiting (alpha-v)(beta-6) integrin BA Harrison, JE Dowling, MG Bursavich, DM Troast, BS Lippa, BN Rogers, ... US Patent App. 17/239,045, 2022 | 2 | 2022 |
| Antagonists of human integrin (α4)(β7) MG Bursavich, DM Troast, BA Harrison, BS Lippa, BN Rogers, KD Konze, ... US Patent 11,174,228, 2021 | 2 | 2021 |
