Viruses as quasispecies: biological implications E Domingo, V Martin, C Perales, A Grande-Perez, J Garcia-Arriaza, ... Quasispecies: concept and implications for virology, 51-82, 2006 | 300 | 2006 |
Evolutionary transition toward defective RNAs that are infectious by complementation J García-Arriaza, SC Manrubia, M Toja, E Domingo, C Escarmís Journal of virology 78 (21), 11678-11685, 2004 | 157 | 2004 |
The evolution of poxvirus vaccines L Sánchez-Sampedro, B Perdiguero, E Mejías-Pérez, J García-Arriaza, ... Viruses 7 (4), 1726-1803, 2015 | 128 | 2015 |
A novel poxvirus-based vaccine, MVA-CHIKV, is highly immunogenic and protects mice against chikungunya infection J García-Arriaza, V Cepeda, D Hallengärd, CÓS Sorzano, BM Kümmerer, ... Journal of Virology 88 (6), 3527-3547, 2014 | 108 | 2014 |
Viral genome segmentation can result from a trade-off between genetic content and particle stability S Ojosnegros, J García-Arriaza, C Escarmís, SC Manrubia, C Perales, ... PLoS Genet 7 (3), e1001344, 2011 | 93 | 2011 |
Rapid selection in modified BHK-21 cells of a foot-and-mouth disease virus variant showing alterations in cell tropism C Escarmís, EC Carrillo, M Ferrer, JFG Arriaza, N Lopez, C Tami, ... Journal of virology 72 (12), 10171-10179, 1998 | 79 | 1998 |
The HIV/AIDS vaccine candidate MVA-B administered as a single immunogen in humans triggers robust, polyfunctional, and selective effector memory T cell responses to HIV-1 antigens CE Gómez, JL Nájera, B Perdiguero, J García-Arriaza, COS Sorzano, ... Journal of virology 85 (21), 11468-11478, 2011 | 78 | 2011 |
Poxvirus vectors as HIV/AIDS vaccines in humans C Elena Gomez, B Perdiguero, J García-Arriaza, M Esteban Human vaccines & immunotherapeutics 8 (9), 1192-1207, 2012 | 76 | 2012 |
A candidate HIV/AIDS vaccine (MVA-B) lacking vaccinia virus gene C6L enhances memory HIV-1-specific T-cell responses J García-Arriaza, JL Nájera, CE Gómez, N Tewabe, COS Sorzano, ... PLoS One 6 (8), e24244, 2011 | 76 | 2011 |
Immunogenic profiling in mice of a HIV/AIDS vaccine candidate (MVA-B) expressing four HIV-1 antigens and potentiation by specific gene deletions J García-Arriaza, JL Nájera, CE Gómez, COS Sorzano, M Esteban PLoS One 5 (8), e12395, 2010 | 75 | 2010 |
Clinical applications of attenuated MVA poxvirus strain CE Gómez, B Perdiguero, J García-Arriaza, M Esteban Expert review of vaccines 12 (12), 1395-1416, 2013 | 73 | 2013 |
Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1 … F García, JCLB de Quirós, CE Gómez, B Perdiguero, JL Nájera, ... Vaccine 29 (46), 8309-8316, 2011 | 71 | 2011 |
Insertion of vaccinia virus C7L host range gene into NYVAC-B genome potentiates immune responses against HIV-1 antigens JL Nájera, CE Gómez, J García-Arriaza, CO Sorzano, M Esteban PLoS one 5 (6), e11406, 2010 | 66 | 2010 |
Prime-boost immunization strategies against Chikungunya virus D Hallengärd, FM Lum, BM Kümmerer, A Lulla, V Lulla, J García-Arriaza, ... Journal of virology 88 (22), 13333-13343, 2014 | 65 | 2014 |
Improving adaptive and memory immune responses of an HIV/AIDS vaccine candidate MVA-B by deletion of vaccinia virus genes (C6L and K7R) blocking interferon signaling pathways J García-Arriaza, P Arnáez, CE Gómez, CÓS Sorzano, M Esteban PloS one 8 (6), e66894, 2013 | 65 | 2013 |
Enhancing poxvirus vectors vaccine immunogenicity J García-Arriaza, M Esteban Human vaccines & immunotherapeutics 10 (8), 2235-2244, 2014 | 62 | 2014 |
Molecular basis for a lack of correlation between viral fitness and cell killing capacity M Herrera, J García-Arriaza, N Pariente, C Escarmís, E Domingo PLoS Pathog 3 (4), e53, 2007 | 55 | 2007 |
Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1 B Mothe, N Climent, M Plana, M Rosàs, JL Jiménez, ... Journal of Antimicrobial Chemotherapy 70 (6), 1833-1842, 2015 | 51 | 2015 |
Dynamics of mutation and recombination in a replicating population of complementing, defective viral genomes J García-Arriaza, S Ojosnegros, M Dávila, E Domingo, C Escarmís Journal of molecular biology 360 (3), 558-572, 2006 | 50 | 2006 |
Deletion of the vaccinia virus N2L gene encoding an inhibitor of IRF3 improves the immunogenicity of modified vaccinia virus Ankara expressing HIV-1 antigens J García-Arriaza, CE Gómez, CÓS Sorzano, M Esteban Journal of virology 88 (6), 3392-3410, 2014 | 40 | 2014 |