| Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci JB Harley, ME Alarcón-Riquelme, LA Criswell, CO Jacob, RP Kimberly, ... Nature genetics 40 (2), 204-210, 2008 | 1447 | 2008 |
| A molecular basis for MHC class II--associated autoimmunity JA Todd, H Acha-Orbea, JI Bell, N Chao, Z Fronek, CO Jacob, ... Science 240 (4855), 1003-1009, 1988 | 879 | 1988 |
| Evidence for the involvement of interleukin 6 in experimental cancer cachexia. G Strassmann, M Fong, JS Kenney, CO Jacob The Journal of clinical investigation 89 (5), 1681-1684, 1992 | 859 | 1992 |
| Tumour necrosis factor-α in murine autoimmune'lupus' nephritis CO Jacob, HO McDevitt Nature 331 (6154), 356-358, 1988 | 797 | 1988 |
| Human polymorphism at microRNAs and microRNA target sites. L Yang, C Lin, C Jin, JC Yang, B Tanasa, WWH Li, D Merkurjev, J Zhang, ... Frontiers in Genetics 4 (3), 2062-74, 2013 | 777* | 2013 |
| Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus … CO Jacob, Z Fronek, GD Lewis, M Koo, JA Hansen, HO McDevitt Proceedings of the National Academy of Sciences 87 (3), 1233-1237, 1990 | 770 | 1990 |
| Insulin-Dependent Diabetes Mellitus (IDDM) Is Associated with CTLA4 Polymorphisms in Multiple Ethnic Groups MP Marron, LJ Raffel, HJ Garchon, CO Jacob, M Serrano-Rios, ... Human molecular genetics 6 (8), 1275-1282, 1997 | 507 | 1997 |
| INVIVO TREATMENT OF (NZBXNZW) F1 LUPUS-LIKE NEPHRITIS WITH MONOCLONAL-ANTIBODY TO GAMMA-INTERFERON CO Jacob, PH Vandermeide, HO McDevitt Journal of Experimental Medicine 166 (3), 798-803, 1987 | 479 | 1987 |
| In vivo treatment of (NZB X NZW) F1 lupus-like nephritis with monoclonal antibody to gamma interferon. CO Jacob, PH Van der Meide, HO McDevitt The Journal of experimental medicine 166 (3), 798-803, 1987 | 479 | 1987 |
| Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. CO Jacob, S Aiso, SA Michie, HO Mcdevitt, H Acha-Orbea Proceedings of the National Academy of Sciences 87 (3), 968-972, 1990 | 452 | 1990 |
| Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families R Shai, FP Quismorio Jr, L Li, OJ Kwon, J Morrison, DJ Wallace, ... Human Molecular Genetics 8 (4), 639-644, 1999 | 376 | 1999 |
| Immune response to cholera toxin epitope inserted in Salmonella flagellin SM Newton, CO Jacob, BA Stocker Science 244 (4900), 70-72, 1989 | 345 | 1989 |
| Transancestral mapping and genetic load in systemic lupus erythematosus CD Langefeld, HC Ainsworth, DSC Graham, JA Kelly, ME Comeau, ... Nature communications 8 (1), 1-18, 2017 | 343 | 2017 |
| Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus I Adrianto, F Wen, A Templeton, G Wiley, JB King, CJ Lessard, JS Bates, ... Nature genetics 43 (3), 253-258, 2011 | 298 | 2011 |
| Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus CO Jacob, J Zhu, DL Armstrong, M Yan, J Han, XJ Zhou, JA Thomas, ... Proceedings of the National Academy of Sciences 106 (15), 6256-6261, 2009 | 286 | 2009 |
| Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort B Namjou, PH Kothari, JA Kelly, SB Glenn, JO Ojwang, A Adler, ... Genes & Immunity 12 (4), 270-279, 2011 | 273 | 2011 |
| Differential genetic associations for systemic lupus erythematosus based on anti–dsDNA autoantibody production SA Chung, KE Taylor, RR Graham, J Nititham, AT Lee, WA Ortmann, ... PLoS Genet 7 (3), e1001323, 2011 | 233 | 2011 |
| Synergistic effect between IL‐10 and bcl‐2 genotypes in determining susceptibility to systemic lupus erythematosus R Mehrian, FP Quismorio Jr, G Strassmann, MM Stimmler, DA Horwitz, ... Arthritis & Rheumatism: Official Journal of the American College of …, 1998 | 231 | 1998 |
| Synergistic effect between IL-10 and BCL-2 genotypes in determining susceptibility to SLE. R Mehrian, F Ouismorio, G Strassmann, M Stimmler, D Horwitz, R Kitridou, ... Arthritis & Rheumatism 40 (9), 1997 | 231* | 1997 |
| Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility J Zhao, H Wu, M Khosravi, H Cui, X Qian, JA Kelly, KM Kaufman, ... PLoS Genet 7 (5), e1002079, 2011 | 215 | 2011 |
