| Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ř and Side-Chain ÷1 and ÷2 Dihedral Angles RB Best, X Zhu, J Shim, PEM Lopes, J Mittal, M Feig, AD MacKerell Jr Journal of chemical theory and computation 8 (9), 3257-3273, 2012 | 4044 | 2012 |
| ALS Mutations Disrupt Phase Separation Mediated by á-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain AE Conicella, GH Zerze, J Mittal, NL Fawzi Structure 24 (9), 1537-1549, 2016 | 711 | 2016 |
| Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association RB Best, W Zheng, J Mittal Journal of chemical theory and computation 10 (11), 5113-5124, 2014 | 618 | 2014 |
| Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ... The EMBO journal 36 (20), 2951-2967, 2017 | 580 | 2017 |
| Molecular interactions underlying liquid− liquid phase separation of the FUS low-complexity domain AC Murthy, GL Dignon, Y Kan, GH Zerze, SH Parekh, J Mittal, NL Fawzi Nature Structural & Molecular Biology 26 (7), 637, 2019 | 482 | 2019 |
| Sequence determinants of protein phase behavior from a coarse-grained model GL Dignon, W Zheng, YC Kim, RB Best, J Mittal PLoS computational biology 14 (1), e1005941, 2018 | 414 | 2018 |
| Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties GL Dignon, RB Best, J Mittal Annual Review of Physical Chemistry 71, 53-75, 2020 | 375 | 2020 |
| Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation VH Ryan, GL Dignon, GH Zerze, CV Chabata, R Silva, AE Conicella, ... Molecular cell 69 (3), 465-479. e7, 2018 | 338 | 2018 |
| Protein simulations with an optimized water model: cooperative helix formation and temperature-induced unfolded state collapse RB Best, J Mittal The Journal of Physical Chemistry B 114 (46), 14916-14923, 2010 | 277 | 2010 |
| Relation between single-molecule properties and phase behavior of intrinsically disordered proteins GL Dignon, W Zheng, RB Best, YC Kim, J Mittal Proceedings of the National Academy of Sciences 115 (40), 9929-9934, 2018 | 271 | 2018 |
| TDP-43 á-helical structure tunes liquid–liquid phase separation and function AE Conicella, GL Dignon, GH Zerze, HB Schmidt, AM D˘Ordine, YC Kim, ... Proceedings of the National Academy of Sciences 117 (11), 5883-5894, 2020 | 268 | 2020 |
| Temperature-controlled liquid–liquid phase separation of disordered proteins GL Dignon, W Zheng, YC Kim, J Mittal ACS central science 5 (5), 821-830, 2019 | 203 | 2019 |
| Layering and position-dependent diffusive dynamics of confined fluids J Mittal, TM Truskett, JR Errington, G Hummer Physical review letters 100 (14), 145901, 2008 | 202 | 2008 |
| Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior BS Schuster, GL Dignon, WS Tang, FM Kelley, AK Ranganath, ... Proceedings of the National Academy of Sciences 117 (21), 11421-11431, 2020 | 193 | 2020 |
| Excess-entropy-based anomalies for a waterlike fluid JR Errington, TM Truskett, J Mittal The Journal of chemical physics 125 (24), 2006 | 189 | 2006 |
| A carbon nanotube reporter of microRNA hybridization events in vivo JD Harvey, PV Jena, HA Baker, GH Zerze, RM Williams, TV Galassi, ... Nature Biomedical Engineering 1, 0041, 2017 | 188 | 2017 |
| Temperature-dependent solvation modulates the dimensions of disordered proteins R Wuttke, H Hofmann, D Nettels, MB Borgia, J Mittal, RB Best, B Schuler Proceedings of the National Academy of Sciences 111 (14), 5213-5218, 2014 | 186 | 2014 |
| Thermodynamics and kinetics of protein folding under confinement J Mittal, RB Best Proceedings of the National Academy of Sciences 105 (51), 20233-20238, 2008 | 181 | 2008 |
| Thermodynamics predicts how confinement modifies the dynamics of the equilibrium hard-sphere fluid J Mittal, JR Errington, TM Truskett Physical review letters 96 (17), 177804, 2006 | 165 | 2006 |
| Static and dynamic correlations in water at hydrophobic interfaces J Mittal, G Hummer Proceedings of the National Academy of Sciences 105 (51), 20130-20135, 2008 | 157 | 2008 |
Robert BestSenior Investigator, National Institutes of HealthVerified email at helix.nih.gov
