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George Kokotos
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Phospholipase A2 Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
EA Dennis, J Cao, YH Hsu, V Magrioti, G Kokotos
Chemical reviews 111 (10), 6130-6185, 2011
9862011
Cytosolic group IVA and calcium-independent group VIA phospholipase A2s act on distinct phospholipid pools in zymosan-stimulated mouse peritoneal macrophages
L Gil-de-Gómez, AM Astudillo, C Guijas, V Magrioti, G Kokotos, ...
The Journal of Immunology 192 (2), 752-762, 2014
1382014
A Convenient One-Pot Conversion of-Protected Amino Acids and Peptides into Alcohols
G Kokotos
Synthesis 1990 (4), 299-301, 1990
1261990
Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases
V Magrioti, G Kokotos
Expert opinion on therapeutic patents 20 (1), 1-18, 2010
1192010
Enantiospecific synthesis of α-amino acid semialdehydes: a key step for the synthesis of unnatural unsaturated and saturated α-amino acids
JM Padrón, G Kokotos, T Martı́n, T Markidis, WA Gibbons, VS Martı́n
Tetrahedron: Asymmetry 9 (19), 3381-3394, 1998
1171998
A general approach to the asymmetric synthesis of unsaturated lipidic α-amino acids. The first synthesis of α-aminoarachidonic acid
G Kokotos, JM Padrón, T Martín, WA Gibbons, VS Martín
The Journal of Organic Chemistry 63 (11), 3741-3744, 1998
1161998
Synthetic and Natural Inhibitors of Phospholipases A2: Their Importance for Understanding and Treatment of Neurological Disorders
WY Ong, T Farooqui, G Kokotos, AA Farooqui
ACS chemical neuroscience 6 (6), 814-831, 2015
1132015
Selective one-pot conversion of carboxylic acids into alcohols
G Kokotos, C Noula
The Journal of Organic Chemistry 61 (20), 6994-6996, 1996
1091996
Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer
E Barbayianni, E Kaffe, V Aidinis, G Kokotos
Progress in lipid research 58, 76-96, 2015
1072015
Inhibition of Group IVA Cytosolic Phospholipase A2 by Novel 2-Oxoamides in Vitro, in Cells, and in Vivo
G Kokotos, DA Six, V Loukas, T Smith, V Constantinou-Kokotou, ...
Journal of medicinal chemistry 47 (14), 3615-3628, 2004
1012004
Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis
A Kalyvas, C Baskakis, V Magrioti, V Constantinou-Kokotou, D Stephens, ...
Brain 132 (5), 1221-1235, 2009
992009
Novel 2-Oxoamide Inhibitors of Human Group IVA Phospholipase A2
G Kokotos, S Kotsovolou, DA Six, V Constantinou-Kokotou, CC Beltzner, ...
Journal of medicinal chemistry 45 (14), 2891-2893, 2002
982002
Potent and Selective Fluoroketone Inhibitors of Group VIA Calcium-Independent Phospholipase A2
G Kokotos, YH Hsu, JE Burke, C Baskakis, CG Kokotos, V Magrioti, ...
Journal of medicinal chemistry 53 (9), 3602-3610, 2010
942010
Structure−Activity Relationship of 2-Oxoamide Inhibition of Group IVA Cytosolic Phospholipase A2 and Group V Secreted Phospholipase A2
DA Six, E Barbayianni, V Loukas, V Constantinou-Kokotou, ...
Journal of medicinal chemistry 50 (17), 4222-4235, 2007
902007
4-Substituted prolines as organocatalysts for aldol reactions
E Bellis, G Kokotos
Tetrahedron 61 (36), 8669-8676, 2005
882005
Primary Amine‐Thioureas based on tert‐Butyl Esters of Natural Amino Acids as Organocatalysts for the Michael Reaction
CG Kokotos, G Kokotos
Advanced Synthesis & Catalysis 351 (9), 1355-1362, 2009
842009
Synthesis and Study of a Lipophilic α-Keto Amide Inhibitor of Pancreatic Lipase
A Chiou, T Markidis, V Constantinou-Kokotou, R Verger, G Kokotos
Organic Letters 2 (3), 347-350, 2000
842000
Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release
TL Yaksh, G Kokotos, CI Svensson, D Stephens, CG Kokotos, ...
Journal of Pharmacology and Experimental Therapeutics 316 (1), 466-475, 2006
802006
Proline-modified poly (propyleneimine) dendrimers as catalysts for asymmetric aldol reactions
E Bellis, G Kokotos
Journal of Molecular Catalysis A: Chemical 241 (1-2), 166-174, 2005
782005
Sulfonamides of homoproline and dipeptides as organocatalysts for Michael and aldol reactions
E Tsandi, CG Kokotos, S Kousidou, V Ragoussis, G Kokotos
Tetrahedron 65 (7), 1444-1449, 2009
772009
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