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Gretchen Seim
Gretchen Seim
Verified email at wisc.edu
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Year
Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-ã stimulation
GL Seim, EC Britt, SV John, FJ Yeo, AR Johnson, RS Eisenstein, ...
Nature metabolism 1 (7), 731-742, 2019
1072019
Switching to the cyclic pentose phosphate pathway powers the oxidative burst in activated neutrophils
EC Britt, J Lika, MA Giese, TJ Schoen, GL Seim, Z Huang, PY Lee, ...
Nature metabolism 4 (3), 389-403, 2022
722022
Bioavailability of iron in geophagic earths and clay minerals, and their effect on dietary iron absorption using an in vitro digestion/Caco-2 cell model
GL Seim, CI Ahn, MS Bodis, F Luwedde, DD Miller, S Hillier, E Tako, ...
Food & function 4 (8), 1263-1270, 2013
412013
Promoter demethylation of the asparagine synthetase gene is required for ATF4-dependent adaptation to asparagine depletion
J Jiang, S Srivastava, G Seim, NN Pavlova, B King, L Zou, C Zhang, ...
Journal of Biological Chemistry 294 (49), 18674-18684, 2019
352019
Translating formative research findings into a behaviour change strategy to promote antenatal calcium and iron and folic acid supplementation in western Kenya
SL Martin, GL Seim, S Wawire, GM Chapleau, SL Young, KL Dickin
Maternal & child nutrition 13 (1), 2017
312017
Discovering how heme controls genome function through heme-omics
R Liao, Y Zheng, X Liu, Y Zhang, G Seim, N Tanimura, GM Wilson, ...
Cell reports 31 (13), 2020
252020
Soil consumed by chacma baboons is low in bioavailable iron and high in clay
PA Pebsworth, GL Seim, MA Huffman, RP Glahn, E Tako, SL Young
Journal of chemical ecology 39, 447-449, 2013
232013
Adapting the T rials of I mproved P ractices (TIP s) approach to explore the acceptability and feasibility of nutrition and parenting recommendations: what works for low‐income …
KL Dickin, G Seim
Maternal & child nutrition 11 (4), 897-914, 2015
202015
A Novel in Vivo Model for Assessing the Impact of Geophagic Earth on Iron Status
GL Seim, E Tako, C Ahn, RP Glahn, SL Young
Nutrients 8 (6), 362, 2016
172016
Nitric oxide-driven modifications of lipoic arm inhibit á-ketoacid dehydrogenases
GL Seim, SV John, NL Arp, Z Fang, DJ Pagliarini, J Fan
Nature Chemical Biology 19 (3), 265-274, 2023
132023
A matter of time: temporal structure and functional relevance of macrophage metabolic rewiring
GL Seim, J Fan
Trends in Endocrinology & Metabolism 33 (5), 345-358, 2022
102022
Metabolomic and lipidomic analysis of bone marrow derived macrophages
GL Seim, SV John, J Fan
Bio-protocol 10 (14), e3693-e3693, 2020
72020
Asparagine bioavailability regulates the translation of MYC oncogene
S Srivastava, J Jiang, J Misra, G Seim, KA Staschke, M Zhong, L Zhou, ...
Oncogene 41 (44), 4855-4865, 2022
52022
Analysis of arginine metabolism using LC-MS and isotopic labeling
GL Seim, EC Britt, J Fan
High-Throughput Metabolomics: Methods and Protocols, 199-217, 2019
32019
Reactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism
NL Arp, GL Seim, JA Votava, J Josephson, J Fan
Journal of Biological Chemistry 299 (11), 2023
12023
Asparagine starvation suppresses histone demethylation through iron depletion
J Jiang, S Srivastava, S Liu, G Seim, R Claude, M Zhong, S Cao, U Davé, ...
Iscience 26 (4), 2023
12023
Modifications of lipoic arm by reactive nitrogen species regulate á-ketoacid dehydrogenases
GL Seim, Z Fang, DJ Pagliarini, J Fan
BioRxiv, 2022.01. 31.478543, 2022
12022
Macrophages undergo functionally significant reprogramming of nucleotide metabolism upon classical activation
SV John, GL Seim, BJ Erazo-Flores, J Steill, J Freeman, JA Votava, ...
bioRxiv, 2023.12. 27.573447, 2023
2023
Asparagine Bioavailability Regulates the Translation of MYC oncogene in Lymphoid Malignancies
S Srivastava, J Jiang, G Seim, J Misra, U Dave, R Kapur, J Zhou, J Fan, ...
Blood 140 (Supplement 1), 3040-3041, 2022
2022
Dynamic Metabolic Rewiring in Macrophages in Response to Pro-Inflammatory Stimulation
GL Seim
The University of Wisconsin-Madison, 2022
2022
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