A motif for quinone binding sites in respiratory and photosynthetic systems N Fisher, PR Rich Journal of molecular biology 296 (4), 1153-1162, 2000 | 207 | 2000 |
Antimalarial pharmacology and therapeutics of atovaquone GL Nixon, DM Moss, AE Shone, DG Lalloo, N Fisher, PM O'Neill, SA Ward, ... Journal of Antimicrobial Chemotherapy 68 (5), 977-985, 2013 | 202 | 2013 |
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria GA Biagini, N Fisher, AE Shone, MA Mubaraki, A Srivastava, A Hill, ... Proceedings of the National Academy of Sciences 109 (21), 8298-8303, 2012 | 192 | 2012 |
Molecular basis of resistance to cytochrome bc1 inhibitors N Fisher, B Meunier FEMS yeast research 8 (2), 183-192, 2008 | 182 | 2008 |
Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential T Antoine, N Fisher, R Amewu, PM O'Neill, SA Ward, GA Biagini Journal of Antimicrobial Chemotherapy 69 (4), 1005-1016, 2014 | 149 | 2014 |
Inhibiting Plasmodium cytochrome bc1: a complex issue V Barton, N Fisher, GA Biagini, SA Ward, PM O˘Neill Current opinion in chemical biology 14 (4), 440-446, 2010 | 144 | 2010 |
Chloroplast ATP Synthase Modulation of the Thylakoid Proton Motive Force: Implications for Photosystem I and Photosystem II Photoprotection A Kanazawa, E Ostendorf, K Kohzuma, D Hoh, DD Strand, M Sato-Cruz, ... Frontiers in Plant Science 8, 719, 2017 | 132 | 2017 |
Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum Type II NADH: quinone oxidoreductase (PfNDH2) C Pidathala, R Amewu, B Pacorel, GL Nixon, P Gibbons, WD Hong, ... Journal of medicinal chemistry 55 (5), 1831-1843, 2012 | 129 | 2012 |
A mitochondrial cytochrome b mutation causing severe respiratory chain enzyme deficiency in humans and yeast EL Blakely, AL Mitchell, N Fisher, B Meunier, LG Nijtmans, AM Schaefer, ... FEBS journal 272 (14), 3583-3592, 2005 | 126 | 2005 |
Antimalarial 4 (1H)-pyridones bind to the Qi site of cytochrome bc1 MJ Capper, PM O˘Neill, N Fisher, RW Strange, D Moss, SA Ward, ... Proceedings of the National Academy of Sciences 112 (3), 755-760, 2015 | 123 | 2015 |
Acridinediones: selective and potent inhibitors of the malaria parasite mitochondrial bc1 complex GA Biagini, N Fisher, N Berry, PA Stocks, B Meunier, DP Williams, ... Molecular Pharmacology 73 (5), 1347-1355, 2008 | 122 | 2008 |
The higher plant plastid NAD(P)H dehydrogenase-like complex (NDH) is a high efficiency proton pump that increases ATP production by cyclic electron flow DD Strand, N Fisher, DM Kramer Journal of Biological Chemistry, jbc. M116. 770792, 2017 | 121 | 2017 |
Cytochrome b Mutation Y268S Conferring Atovaquone Resistance Phenotype in Malaria Parasite Results in Reduced Parasite bc1 Catalytic Turnover and Protein Expression N Fisher, RA Majid, T Antoine, M Al-Helal, AJ Warman, DJ Johnson, ... Journal of Biological Chemistry 287 (13), 9731-9741, 2012 | 112 | 2012 |
The malaria parasite type II NADH: quinone oxidoreductase: an alternative enzyme for an alternative lifestyle N Fisher, PG Bray, SA Ward, GA Biagini Trends in parasitology 23 (7), 305-310, 2007 | 107 | 2007 |
Re‐examination of inhibitor resistance conferred by Qo‐site mutations in cytochrome b using yeast as a model system N Fisher, B Meunier Pest management science 61 (10), 973-978, 2005 | 107 | 2005 |
Modeling the Qo site of crop pathogens in Saccharomyces cerevisiae cytochrome b N Fisher, AC Brown, G Sexton, A Cook, J Windass, B Meunier European Journal of Biochemistry 271 (11), 2264-2271, 2004 | 100 | 2004 |
Respiratory complex III dysfunction in humans and the use of yeast as a model organism to study mitochondrial myopathy and associated diseases B Meunier, N Fisher, S Ransac, JP Mazat, G Brasseur Biochimica et Biophysica Acta (BBA)-Bioenergetics 1827 (11), 1346-1361, 2013 | 95 | 2013 |
Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era GL Nixon, C Pidathala, AE Shone, T Antoine, N Fisher, PM O'Neill, ... Future medicinal chemistry 5 (13), 1573-1591, 2013 | 86 | 2013 |
Human disease-related mutations in cytochrome b studied in yeast N Fisher, CK Castleden, I Bourges, G Brasseur, G Dujardin, B Meunier Journal of Biological Chemistry 279 (13), 12951-12958, 2004 | 85 | 2004 |
Effects of mutations in mitochondrial cytochrome b in yeast and man N Fisher, B Meunier European Journal of Biochemistry 268 (5), 1155-1162, 2001 | 81 | 2001 |