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Hongzhong Lu
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A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism
H Lu, F Li, BJ Sánchez, Z Zhu, G Li, I Domenzain, S Marcišauskas, ...
Nature communications 10 (1), 3586, 2019
2622019
Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces
W Wang, S Li, Z Li, J Zhang, K Fan, G Tan, G Ai, SM Lam, G Shui, Z Yang, ...
Nature biotechnology 38 (1), 76-83, 2020
1492020
Deep learning-based kcat prediction enables improved enzyme-constrained model reconstruction
F Li, L Yuan, H Lu, G Li, Y Chen, MKM Engqvist, EJ Kerkhoven, J Nielsen
Nature Catalysis 5 (8), 662-672, 2022
1302022
Integrated isotope-assisted metabolomics and 13C metabolic flux analysis reveals metabolic flux redistribution for high glucoamylase production by Aspergillus niger
H Lu, X Liu, M Huang, J Xia, J Chu, Y Zhuang, S Zhang, H Noorman
Microbial Cell Factories 14, 1-14, 2015
432015
Comprehensive reconstruction and in silico analysis of Aspergillus niger genome‐scale metabolic network model that accounts for 1210 ORFs
H Lu, W Cao, L Ouyang, J Xia, M Huang, J Chu, Y Zhuang, S Zhang, ...
Biotechnology and Bioengineering 114 (3), 685-695, 2017
412017
Multi-omics integrative analysis with genome-scale metabolic model simulation reveals global cellular adaptation of Aspergillus niger under industrial enzyme …
H Lu, W Cao, X Liu, Y Sui, L Ouyang, J Xia, M Huang, Y Zhuang, S Zhang, ...
Scientific reports 8 (1), 14404, 2018
362018
Comprehensive reconstruction and evaluation of Pichia pastoris genome-scale metabolic model that accounts for 1243 ORFs
R Ye, M Huang, H Lu, J Qian, W Lin, J Chu, Y Zhuang, S Zhang
Bioresources and Bioprocessing 4, 1-12, 2017
312017
Multiscale models quantifying yeast physiology: towards a whole-cell model
H Lu, EJ Kerkhoven, J Nielsen
Trends in Biotechnology 40 (3), 291-305, 2022
262022
Improvement of glucoamylase production using axial impellers with low power consumption and homogeneous mass transfer
W Tang, A Pan, H Lu, J Xia, Y Zhuang, S Zhang, J Chu, H Noorman
Biochemical engineering journal 99, 167-176, 2015
262015
Engineering cofactor metabolism for improved protein and glucoamylase production in Aspergillus niger
Y Sui, T Schütze, L Ouyang, H Lu, P Liu, X Xiao, J Qi, YP Zhuang, ...
Microbial Cell Factories 19, 1-17, 2020
212020
Dependence of fungal characteristics on seed morphology and shear stress in bioreactors
H Lu, C Li, W Tang, Z Wang, J Xia, S Zhang, Y Zhuang, J Chu, ...
Bioprocess and biosystems engineering 38, 917-928, 2015
212015
Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection
H Lu, F Li, L Yuan, I Domenzain, R Yu, H Wang, G Li, Y Chen, B Ji, ...
Molecular Systems Biology 17 (10), e10427, 2021
182021
Integrated analysis of the yeast NADPH-regulator Stb5 reveals distinct differences in NADPH requirements and regulation in different states of yeast metabolism
L Ouyang, P Holland, H Lu, D Bergenholm, J Nielsen
FEMS yeast research 18 (8), foy091, 2018
172018
A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism. Nat Commun. 2019; 10: 3586
H Lu, F Li, BJ Sánchez, Z Zhu, G Li, I Domenzain, S Marcišauskas, ...
132019
Multi-scale data-driven engineering for biosynthetic titer improvement
Z Cao, J Yu, W Wang, H Lu, X Xia, H Xu, X Yang, L Bao, Q Zhang, ...
Current Opinion in Biotechnology 65, 205-212, 2020
112020
Improving cytosolic aspartate biosynthesis increases glucoamylase production in Aspergillus niger under oxygen limitation
W Cao, G Wang, H Lu, L Ouyang, J Chu, Y Sui, Y Zhuang
Microbial Cell Factories 19, 1-14, 2020
102020
1, 3-Diphenyldisiloxane Enables Additive-Free Redox Recycling Reactions and Catalysis with Triphenylphosphine
JA Buonomo, MS Cole, CG Eiden, CC Aldrich
Synthesis 52 (23), 3583-3594, 2020
62020
HGTphyloDetect: facilitating the identification and phylogenetic analysis of horizontal gene transfer
L Yuan, H Lu, F Li, J Nielsen, EJ Kerkhoven
Briefings in Bioinformatics 24 (2), bbad035, 2023
52023
Construction and application of black-box model for glucoamylase production by Aspergillus niger
L Li, H Lu, J Xia, J Chu, Y Zhuang, S Zhang
Sheng wu Gong Cheng xue bao= Chinese Journal of Biotechnology 31 (7), 1089-1098, 2015
52015
Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing
L Jiang, T Zhang, H Lu, S Li, K Lv, A Tuffour, L Zhang, K Ding, JP Li, H Li, ...
Synthetic and Systems Biotechnology 8 (1), 11-19, 2023
42023
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