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Iñigo Apaolaza
Iñigo Apaolaza
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Year
Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v. 3.0
L Heirendt, S Arreckx, T Pfau, SN Mendoza, A Richelle, A Heinken, ...
Nature protocols, 1, 2019
9772019
CANCERTOOL: a visualization and representation interface to exploit cancer datasets
AR Cortazar, V Torrano, N Martín-Martín, A Caro-Maldonado, L Camacho, ...
Cancer research 78 (21), 6320-6328, 2018
902018
An in-silico approach to predict and exploit synthetic lethality in cancer metabolism
I Apaolaza, E San José-Eneriz, L Tobalina, E Miranda, L Garate, X Agirre, ...
Nature communications 8 (1), 1-9, 2017
562017
An extended reconstruction of human gut microbiota metabolism of dietary compounds
T Blasco, S Pérez-Burillo, F Balzerani, D Hinojosa-Nogueira, ...
Nature Communications 12 (1), 4728, 2021
242021
gMCS: fast computation of genetic minimal cut sets in large networks
I Apaolaza, LV Valcarcel, FJ Planes
Bioinformatics 35 (3), 535-537, 2019
222019
Adaptation of the human gut microbiota metabolic network during the first year after birth
Á Fuertes, S Pérez-Burillo, I Apaolaza, Y Vallès, MP Francino, ...
Frontiers in Microbiology 10, 848, 2019
182019
In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer
J Pey, E San José-Eneriz, MC Ochoa, I Apaolaza, P de Atauri, A Rubio, ...
Scientific reports 7 (1), 1-10, 2017
152017
Prediction of degradation pathways of phenolic compounds in the human gut microbiota through enzyme promiscuity methods
F Balzerani, D Hinojosa-Nogueira, X Cendoya, T Blasco, S Pérez-Burillo, ...
npj Systems Biology and Applications 8 (1), 24, 2022
72022
Effect of Freezing on Gut Microbiota Composition and Functionality for In Vitro Fermentation Experiments
S Pérez-Burillo, D Hinojosa-Nogueira, B Navajas-Porras, T Blasco, ...
Nutrients 13 (7), 2207, 2021
72021
The bone marrow niche regulates redox and energy balance in MLL:: AF9 leukemia stem cells
AC Viñado, IA Calvo, I Cenzano, D Olaverri, M Cocera, P San Martin-Uriz, ...
Leukemia 36 (8), 1969-1979, 2022
62022
On the inconsistent treatment of gene-protein-reaction rules in context-specific metabolic models
M Ponce-de-León, I Apaolaza, A Valencia, FJ Planes
Bioinformatics 36 (6), 1986, 2020
62020
A network-based approach to integrate nutrient microenvironment in the prediction of synthetic lethality in cancer metabolism
I Apaolaza, E San José-Enériz, LV Valcarcel, X Agirre, F Prosper, ...
PLOS Computational Biology 18 (3), e1009395, 2022
52022
COBRA methods and metabolic drug targets in cancer
I Apaolaza, ES José-Eneriz, X Agirre, F Prósper, FJ Planes
Molecular & Cellular Oncology, e1389672, 2017
52017
Synthetic lethality in large-scale integrated metabolic and regulatory network models of human cells
N Barrena, LV Valcárcel, D Olaverri-Mendizabal, I Apaolaza, FJ Planes
npj Systems Biology and Applications 9 (1), 32, 2023
12023
gMCStool: automated network-based tool to search for metabolic vulnerabilities in cancer
LV Valcárcel, E San José-Enériz, R Ordoñez, I Apaolaza, A Valcárcel, ...
bioRxiv, 2022.11. 03.514827, 2022
12022
Computational Systems Biology Models for the Identification of Metabolic Vulnerabilities in Multiple Myeloma
LVV Valcárcel, R Ordoñez, I Apaolaza, A Valcárcel, L Garate, C Meydan, ...
Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019
2019
genetic Minimal Cut Sets-gMCSs
I Apaolaza, LV Valcarcel, FJ Planes
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Articles 1–17